Abstract: A micro atomizer to produce stable aerosol concentrations having an aerosol mass median aerodynamic diameter (MMAD) of less than 10 microns with liquid flow rates in the microliter per minute range is provided. The micro atomizer includes a liquid channel in the shape of a thick-wall tube and a cap having an aerosol outlet orifice whereby a liquid-gas contact space is formed by the internal surface of the cap and the substantially flat end of the liquid channel. Pressurized carrier gas and the liquid to be aerosolized are allowed to come into contact within a precisely formed liquid-gas contact space. The desired aerosol characteristics are accurately established, stable, and reproducible. In an exemplary embodiment, the micro atomizer is used with a syringe and syringe drive to provide a continuous liquid source for aerosol generation.

Abstract: A containment and test system for extremely toxic substances includes a fume hood, a containment compartment such as glove bag or box, positioned within the fume hood, a source of a non-reactive gas to provide a stable environment within the containment compartment, an inline moisture trap coupled to the source of non-reactive gas to dry the non-reactive gas, an ion neutralizer coupled to the source of non-reactive gas to reduce static charges within the containment compartment, a staging area for preparing test samples, a balance positioned within the containment compartment, a stanchion positioned within the fume hood for holding a test animal, and decontaminating apparatus for safely disposing of any toxic substance residue.