Patents by Inventor Charles Lawrence Cywin

Charles Lawrence Cywin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidine derivatives useful as inhibitors of PKC-theta
    Patent number: 7550473
    Abstract: Disclosed are novel compounds of formula (I): wherein R1, R2 and R3 are as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC-theta, including immunological disorders and type II diabetes. This invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: June 23, 2009
    Assignees: Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Mario G. Cardozo, Derek Cogan, Charles Lawrence Cywin, George Dahmann, Darren DiSalvo, John David Ginn, Anthony S. Prokopowicz, III, Denice M. Spero, Erick Richard Roush Young
  • Substituted tricyclic heterocycles and their uses
    Patent number: 7291733
    Abstract: Disclosed are substituted tricyclic heterocycle compounds of the formulas (I), (II) and (III) shown below, wherein R1, R2, R3 and R4 are described herein, which are active as anti-inflammatory agents.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: November 6, 2007
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles Lawrence Cywin, Roman Wolfgang Fleck, Eugene Richard Hickey, Weimin Liu, Tina Marie Morwick, John Robert Proudfoot, Denice M. Spero
  • Pyrimidine derivatives useful as inhibitors of PKC-theta
    Publication number: 20040242613
    Abstract: Disclosed are novel compounds of formula (I): 1
    Type: Application
    Filed: January 27, 2004
    Publication date: December 2, 2004
    Applicants: Boehringer Ingelheim Pharmaceuticals, Inc., Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Mario G. Cardozo, Derek Cogan, Charles Lawrence Cywin, Georg Dahmann, Darren DiSalvo, John David Ginn, Anthony S. Prokopowicz, Denice M. Spero, Erick Young
  • Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
    Publication number: 20040224992
    Abstract: Compounds of Formula (I) 1
    Type: Application
    Filed: February 24, 2004
    Publication date: November 11, 2004
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Charles Lawrence Cywin, Tina Marie Morwick, John Robert Proudfoot, David Thomson