Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.

Abstract: A device for dispensing a viscous fluid from and charging a viscous fluid into a canister mounted on a housing of the device is disclosed. The device comprises a reversible auger-type pump including an auger having first and second ends. The first end of the auger is in communication with a nozzle conduit for conducting a viscous fluid between the first end of the auger and a nozzle provided on the nozzle conduit. The second end of the auger is in communication with the canister. The device further includes a motor and associated gearing for connecting the motor to the auger in driving relationship. Power cell means are provided to supply current to the motor. The polarity of the current so supplied is controllable by a switch so that, when current of a given polarity is supplied to the motor, the auger will rotate in a first direction to fill the canister and when the polarity of the current is reversed, the auger will rotate in the opposite direction to dispense from the canister.

Abstract: A circuit assembly has at least one component comprising a thin film module, or a discrete component, with leads extending therefrom, the assembly also including a substantially planar substrate supporting the component, and at least one connector with a block of electrical insulating material either adhering to or integral with the substrate, and with a plurality of connector pieces, secured to the block, co-operating with the leads, and comprising terminals of the circuit assembly.

Abstract: The flow rate of a diluent fluid, such as steam, hydrogen or methane, to a cracking furnace is controlled so as to maintain a desired outlet velocity for the effluent flowing from the cracking furnace or to maintain a desired residence time for the feed stream in the cracking furnace. Feed forward control for the flow rate of the diluent fluid is provided by using an empirical model of the cracking furnace to predict either the outlet velocity or the residence time based on measured system parameters. Feedback control for the flow rate of the diluent fluid is provided by calculating the actual outlet velocity or actual residence time based on measured system parameters. The measured outlet velocity or residence time is utilized to bias or correct the predicted outlet velocity or residence time to provide a corrected prediction of the outlet or residence time.

Abstract: In a selective hydrogenation process wherein at least two catalyst beds in series are utilized, the temperature of the feed stream to the first catalyst bed and the temperature of the feed stream from the first catalyst bed to the second catalyst bed are manipulated so as to maintain a desired reaction temperature in both catalyst beds. The desired reaction temperature of the first catalyst bed is manipulated so as to insure that a desired percent of a specific feed component is selectively hydrogenated in the first catalyst bed. The reaction temperature of the second catalyst bed is manipulated so as to maintain a desired concentration of the specific feed component in the product stream from the second catalyst bed.

Abstract: The heat supplied to a cracking furnace is controlled so as to maintain a desired conversion rate for the material being cracked in the cracking furnace by comparing a prediction of the conversion rate for the material being cracked in the cracking furnace to a desired conversion rate for the material being cracked in the cracking furnace to thereby determine the heat required to maintain a desired conversion rate for the material being cracked in the cracking furnace. A measured conversion rate for the material being cracked in the cracking furnace is utilized to correct the predicted conversion rate as required. A signal representative of the heat required to maintain a desired conversion rate for the materal being cracking in the cracking furnace is utilized to manipulate the flow of fuel to the cracking furnace to thereby control the heat supplied to the cracking furnace.