Patents by Inventor Charles Nakamura

Charles Nakamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR CARDIOMYOCYTE TRANSPLANTATION
    Publication number: 20240122990
    Abstract: The present disclosure provides for the treatment of cardiac diseases and disorders using in vitro-differentiated cardiomyocytes. Such methods can take advantage of both autologous and allogeneic pluripotent stem cells.
    Type: Application
    Filed: February 22, 2022
    Publication date: April 18, 2024
    Applicant: UNIVERSITY OF WASHINGTON
    Inventors: Charles E. MURRY, William Robb MACLELLAN, Robert Scott THIES, Kenta NAKAMURA, Daisy Sue NAKAMURA, Lauren E. NEIDIG
  • Utilization of fructose in microbial production strains
    Patent number: 7524660
    Abstract: A process has been developed for the utilization of fructose by PTS? microorganisms. Providing the microorganisms with increased fructokinase activity, and optionally with increased fructose transport capacity, allows the microorganisms to use fructose as a nutrient supply with sustained growth. The microbial production of substances such as cell mass, glycerol, and 1,3-propanediol may be achieved during growth in a fructose containing medium using this process.
    Type: Grant
    Filed: May 5, 2005
    Date of Patent: April 28, 2009
    Assignee: E.I. du Pont de Nemours and Company
    Inventors: Perry Caimi, Charles Nakamura
  • FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS
    Publication number: 20070292927
    Abstract: Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein.
    Type: Application
    Filed: April 30, 2007
    Publication date: December 20, 2007
    Inventors: Gail Donaldson, Andrew Eliot, Vasantha Nagarajan, Charles Nakamura, Jean-Francois Tomb
  • FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS
    Publication number: 20070259410
    Abstract: Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein.
    Type: Application
    Filed: April 30, 2007
    Publication date: November 8, 2007
    Inventors: Gail Donaldson, Andrew Eliot, Vasantha Nagarajan, Charles Nakamura, Lixuan Huang
  • Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
    Publication number: 20070048849
    Abstract: A process is provided for the bioconversion of a carbon substrate to 1,3-propanediol by a single organism utilizing microorganisms containing the genes encoding for an active glycerol or diol dehydratase enzyme by contacting these organisms with a carbon substrate under the appropriate fermentation conditions.
    Type: Application
    Filed: October 30, 2006
    Publication date: March 1, 2007
    Inventors: Lisa Laffend, Vasantha Nagarajan, Charles Nakamura
  • Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
    Patent number: 7169588
    Abstract: A new polypropylene terephthalate composition is provided. The polypropylene terephthalate is comprised of 1,3-propanediol and terephthalate. The 1,3-propanediol is produced by the bioconversion of a fermentatble carbon source, preferable glucose. The resulting polypropylene terephthalate is distinguished from petrochemically produced polymer on the basis of dual carbon-isotopic fingerprinting which indicates both the source and the age of the carbon.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: January 30, 2007
    Assignees: E. I. du Pont de Nemours and Company, Genencor International, Inc.
    Inventors: Robert R. Burch, Robert R. Dorsch, Lisa Anne Laffend, Vasantha Nagarajan, Charles Nakamura
  • Utilization of fructose in microbial production strains
    Publication number: 20060252136
    Abstract: A process has been developed for the utilization of fructose by PTS? microorganisms. Providing the microorganisms with increased fructokinase activity, and optionally with increased fructose transport capacity, allows the microorganisms to use fructose as a nutrient supply with sustained growth. The microbial production of substances such as cell mass, glycerol, and 1,3-propanediol may be achieved during growth in a fructose containing medium using this process.
    Type: Application
    Filed: May 5, 2005
    Publication date: November 9, 2006
    Inventors: Perry Caimi, Charles Nakamura
  • 1,3-propanediol and polymer derivatives from a fermentable carbon source
    Publication number: 20030082756
    Abstract: A new polypropylene terephthalate composition is provided. The polypropylene terephthalate is comprised of 1,3-propanediol and terephthalate. The 1,3-propanediol is produced by the bioconversion of a fermentatble carbon source, preferable glucose. The resulting polypropylene terephthalate is distinguished from petrochemically produced polymer on the basis of dual carbon-isotopic fingerprinting which indicates both the source and the age of the carbon.
    Type: Application
    Filed: August 5, 2002
    Publication date: May 1, 2003
    Inventors: Robert R. Burch, Robert R. Dorsch, Lisa Anne Laffend, Vasantha Nagarajan, Charles Nakamura
  • Method for identifying the source of carbon in 1,3-propanediol
    Patent number: 6428767
    Abstract: A new polypropylene terephthalate composition is provided. The polypropylene terephthalate is comprised of 1,3-propanediol and terephthalate. The 1,3-propanediol is produced by the bioconversion of a fermentatble carbon source, preferable glucose. The resulting polypropylene terephthalate is distinguished from petrochemically produced polymer on the basis of dual carbon-isotopic fingerprinting which indicates both the source and the age of the carbon.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: August 6, 2002
    Assignees: E. I. du Pont de Nemours and Company, Genencor International, Inc.
    Inventors: Robert R. Burch, Robert R. Dorsch, Lisa Anne Laffend, Vasantha Nagarajan, Charles Nakamura