Abstract: A tapered helical implantation device for peripheral arteries and other body lumina of locally varying diameter, including struts connected by loops and shaped in a helical winding. The helical winding defines turns and, when expanded, has a first end with a first expanded circumference and a second end with a second expanded circumference greater than the first expanded circumference to form a stent tapering outward from the first end towards the second end. Bridges connect adjacent ones of the turns. The struts, the loops, and the bridges define a series of pores aligned along the helix, the pores having a substantially uniform pore size. The pores has a substantially similar area. The pore size limits a size of a particle that can pass therethrough. In particular, the pore size limits a size of a spherical particle that can pass therethrough.

Abstract: A tapered helical implantation device for peripheral arteries and other body lumina of locally varying diameter, including struts connected by loops and shaped in a helical winding. The helical winding defines turns and, when expanded, has a first end with a first expanded circumference and a second end with a second expanded circumference greater than the first expanded circumference to form a stent tapering outward from the first end towards the second end. Bridges connect adjacent ones of the turns. The struts, the loops, and the bridges define a series of pores aligned along the helix, the pores having a substantially uniform pore size. The pores has a substantially similar area. The pore size limits a size of a particle that can pass therethrough. In particular, the pore size limits a size of a spherical particle that can pass therethrough.

Abstract: An apparatus for the transoral invagination and fundoplication of the stomach to the esophagus includes a clip applier having sharp toothed jaws for grasping and damaging the fundus prior to applying the clip. The clip applier has an overall diameter of less than 7 mm. The clip applier jaws are coupled to a pull wire via a linkage which increases the mechanical advantage and thus permits greater grasping force. A plurality of clip designs are also provided.

Abstract: A medical method includes sliding two substantially straight unconnected arms over a fold of body tissue such that a first arm contacts a first portion of the fold and a second arm contacts a second portion. Then, each arm is bent completely through the fold such that both of the arms compress the portions of the fold into contact with each other. Another method includes releasably coupling first and second substantially linear arms to a bridge, each of the arms having a substantially straight sliding portion and a bendable piercing portion. The arms are slid over opposing sides of two body tissue layers, the first arm sliding over the first layer and the second over the second layer. While the sliding portions of the arms remain substantially straight, each piercing portion is bent completely through the adjacent layer and halfway through the other layer to compress the two layers together.

Abstract: A medical method includes sliding two substantially straight unconnected arms over a fold of body tissue such that a first arm contacts a first portion of the fold and a second arm contacts a second portion. Then, each arm is bent completely through the fold such that both of the arms compress the portions of the fold into contact with each other. Another method includes releasably coupling first and second substantially linear arms to a bridge, each of the arms having a substantially straight sliding portion and a bendable piercing portion. The arms are slid over opposing sides of two body tissue layers, the first arm sliding over the first layer and the second over the second layer. While the sliding portions of the arms remain substantially straight, each piercing portion is bent completely through the adjacent layer and halfway through the other layer to compress the two layers together.

Abstract: Early detection of computer viruses and other message-borne threats is provided by applying heuristic tests to message content and examining sender reputation information when no virus signature information is available. As a result, a messaging gateway can suspend delivery of messages early in a virus outbreak, providing sufficient time for updating an anti-virus checker that can strip virus code from the messages. A dynamic and flexible threat quarantine queue is provided with a variety of exit criteria and exit actions that permits early release of messages in other than first in, first-out order. A message scanning method is described in which early exit from parsing and scanning can occur by matching threat rules only to selected message elements and stopping rule matching as soon as a match on one message element exceeds a threat threshold.

Abstract: An apparatus for the transoral invagination and fundoplication of the stomach to the esophagus includes a clip applier having sharp toothed jaws for grasping and damaging the fundus prior to applying the clip. The clip applier has an overall diameter of less than 7 mm. The clip applier jaws are coupled to a pull wire via a linkage which increases the mechanical advantage and thus permits greater grasping force. A plurality of clip designs are also provided.

Abstract: Controlling a message quarantine is disclosed. A message scanning method is described in which early exit from parsing and scanning can occur by matching threat rules only to selected message elements and stopping rule matching as soon as a match on one message element exceeds a threat threshold.

Abstract: An apparatus for the transoral invagination and fundoplication of the stomach to the esophagus includes a clip applier having sharp toothed jaws for grasping and damaging the fundus prior to applying the clip. The clip applier has an overall diameter of less than 7 mm. The clip applier jaws are coupled to a pull wire via a linkage which increases the mechanical advantage and thus permits greater grasping force. A plurality of clip designs are also provided.

Abstract: A tapered helical implantation device for peripheral arteries and other body lumina of locally varying diameter, including struts connected by loops and shaped in a helical winding. The helical winding defines turns and, when expanded, has a first end with a first expanded circumference and a second end with a second expanded circumference greater than the first expanded circumference to form a stent tapering outward from the first end towards the second end. Bridges connect adjacent ones of the turns. The struts, the loops, and the bridges define a series of pores aligned along the helix, the pores having a substantially uniform pore size. The pores has a substantially similar area. The pore size limits a size of a particle that can pass therethrough. In particular, the pore size limits a size of a spherical particle that can pass therethrough.

Abstract: An apparatus for the transoral invagination and fundoplication of the stomach to the esophagus includes a clip applier having sharp toothed jaws for grasping and damaging the fundus prior to applying the clip. The clip applier has an overall diameter of less than 7 mm. The clip applier jaws are coupled to a pull wire via a linkage which increases the mechanical advantage and thus permits greater grasping force. A plurality of clip designs are also provided.

Abstract: An apparatus for the transoral invagination and fundoplication of the stomach to the esophagus includes a clip applier having sharp toothed jaws for grasping and damaging the fundus prior to applying the clip. The clip applier has an overall diameter of less than 7 mm. The clip applier jaws are coupled to a pull wire via a linkage which increases the mechanical advantage and thus permits greater grasping force. A plurality of clip designs are also provided.

Abstract: Determining whether to quarantine a message is disclosed. A dynamic and flexible threat quarantine queue is provided with a variety of exit criteria and exit actions that permits early release of messages in other than first in, first-out order.

Abstract: A medical method includes sliding two substantially straight unconnected arms over a fold of body tissue such that a first arm contacts a first portion of the fold and a second arm contacts a second portion. Then, each arm is bent completely through the fold such that both of the arms compress the portions of the fold into contact with each other. Another method includes releasably coupling first and second substantially linear arms to a bridge, each of the arms having a substantially straight sliding portion and a bendable piercing portion. The arms are slid over opposing sides of two body tissue layers, the first arm sliding over the first layer and the second over the second layer. While the sliding portions of the arms remain substantially straight, each piercing portion is bent completely through the adjacent layer and halfway through the other layer to compress the two layers together.

Abstract: Methods for infusing the interior of a blood vessel are practiced with a catheter having an infusion lumen, a plurality of elution holes, a movable barrier (preferably an inflatable bladder) between the infusion lumen and the elution holes, an occlusion balloon, and an inflation lumen. The methods include sealing the elution holes with the movable barrier, inserting the catheter into the blood vessel, inflating the occlusion balloon, unsealing the elution holes, injecting the therapeutic agent through the infusion lumen, deflating the occlusion balloon and removing the catheter from the blood vessel. The methods also preferably include testing the occlusion balloon and priming the infusion lumen prior to sealing the infusion ports and inserting the catheter into the blood vessel.

Abstract: Controlling a message quarantine is disclosed. A message scanning method is described in which early exit from parsing and scanning can occur by matching threat rules only to selected message elements and stopping rule matching as soon as a match on one message element exceeds a threat threshold.

Abstract: Early detection of computer viruses and other message-borne threats is provided by applying heuristic tests to message content and examining sender reputation information when no virus signature information is available. As a result, a messaging gateway can suspend delivery of messages early in a virus outbreak, providing sufficient time for updating an anti-virus checker that can strip virus code from the messages. A dynamic and flexible threat quarantine queue is provided with a variety of exit criteria and exit actions that permits early release of messages in other than first in, first-out order. A message scanning method is described in which early exit from parsing and scanning can occur by matching threat rules only to selected message elements and stopping rule matching as soon as a match on one message element exceeds a threat threshold.

Abstract: Endoscopic bipolar scissor blades are formed in a laminate assembly of an electrically conductive electrode, an electrically insulating material, and a metal shearing surface which is electrically insulated and physically spaced from the electrode by the insulating material which is disposed therebetween. In one embodiment, the electrode is a metal blade, while the insulating material is a ceramic which is fixed to the metal blade, and the metal shearing surface which also provides the cutting edge is of a metal material which is fixed to the ceramic. In a second embodiment, the insulating material is a molded ceramic blade, with the electrode and the metal shearing surface layer metalized or otherwise fixed to the ceramic blade. In a third embodiment, the electrode is metalized on a thin layer insulating material which is fixed onto a metallic blade. In a fourth embodiment, metallic shearing and electrode layers are laminated to opposite sides of a fiberglass material.

Abstract: A preferred apparatus for delivering an intravascular drug such as a sclerosing agent (or a microfoam sclerosing agent) to a varicose vein includes a catheter having three concentric tubes. The innermost tube has a guide wire lumen and an inflation lumen. The distal end of the innermost tube has an integral inflatable occlusion balloon in fluid communication with the inflation lumen. The intermediate tube has a lumen through which the innermost tube extends. The distal end of the intermediate tube has a self-expanding balloon with a plurality of fluid pores in fluid communication with the intermediate tube lumen. The outer tube has a lumen through which the intermediate tube extends. Sclerosing agent is dispensed through the intermediate tube to pores located at the distal end of the intermediate tube or in the self-expanding balloon. Veins are sclerosed as the self-expanding balloon is pulled through and ultimately out of the vein.

Abstract: A preferred apparatus for delivering an intravascular drug such as a sclerosing agent (or a microfoam sclerosing agent) to a varicose vein includes a catheter having three concentric tubes. The innermost tube has a guide wire lumen and an inflation lumen. The distal end of the innermost tube has an integral inflatable occlusion balloon in fluid communication with the inflation lumen. The intermediate tube has a lumen through which the innermost tube extends. The distal end of the intermediate tube has a self-expanding balloon with a plurality of fluid pores in fluid communication with the intermediate tube lumen. The outer tube has a lumen through which the intermediate tube extends. Sclerosing agent is dispensed through the intermediate tube to pores located at the distal end of the intermediate tube or in the self-expanding balloon. Veins are sclerosed as the self-expanding balloon is pulled through and ultimately out of the vein.