Patents by Inventor Charles Wyatt Shields, IV

Charles Wyatt Shields, IV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS RELATING TO MACROPHAGES AND/OR MONOCYTES WITH ADHERED PARTICLES
    Publication number: 20200376137
    Abstract: Provided herein are polymeric particles and compositions (i.e., “backpacks”) that can adhere to cells and provide delivery of payload immunomodulatory agents to those cells. For examples, the particles can adhere to macrophages and/or monocytes and release cytokines that promote an M1 or M2 phenotype to improve therapeutic efficacy of the cells.
    Type: Application
    Filed: January 8, 2019
    Publication date: December 3, 2020
    Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, The Regents of the University of California on behalf of its Santa Barbara campus
    Inventors: Samir MITRAGOTRI, Michael Andrew EVANS, Charles Wyatt SHIELDS IV
  • Acoustically Responsive Particles
    Publication number: 20200355677
    Abstract: Acoustically responsive particles and methods are provided for their use. Methods are provided for making and using tunable, monodisperse acoustically responsive particles and negative contrast acoustic particles, wherein the particles can contain a functional group available for covalent modification.
    Type: Application
    Filed: July 29, 2020
    Publication date: November 12, 2020
    Inventors: Leah M Johnson, Gabriel Lopez, Lu Gao, Charles Wyatt Shields, IV
  • ACOUSTICALLY RESPONSIVE PARTICLES
    Publication number: 20180120307
    Abstract: Acoustically responsive particles and methods are provided for their use. Methods are provided for making and using tunable, monodisperse acoustically responsive particles and negative contrast acoustic particles, wherein the particles can contain a functional group available for covalent modification.
    Type: Application
    Filed: October 24, 2017
    Publication date: May 3, 2018
    Inventors: Leah M. Johnson, Gabriel P. Lopez, Lu Gao, Charles Wyatt Shields, IV
  • Acoustically responsive particles
    Patent number: 9797897
    Abstract: Acoustically responsive particles and methods are provided for their use. Methods are provided for making and using tunable, monodisperse acoustically responsive particles and negative contrast acoustic particles, wherein the particles can contain a functional group available for covalent modification.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: October 24, 2017
    Assignee: DUKE UNIVERSITY
    Inventors: Leah M. Johnson, Gabriel P. Lopez, Lu Gao, Charles Wyatt Shields, IV
  • ACOUSTICALLY RESPONSIVE PARTICLES
    Publication number: 20150118692
    Abstract: Acoustically responsive particles and methods are provided for their use. Methods are provided for making and using tunable, monodisperse acoustically responsive particles and negative contrast acoustic particles, wherein the particles can contain a functional group available for covalent modification.
    Type: Application
    Filed: March 15, 2013
    Publication date: April 30, 2015
    Inventors: Leah M. Johnson, Gabriel P. Lopez, Lu Gao, Charles Wyatt Shields, IV