Patents by Inventor Charlie R. Mantel

Charlie R. Mantel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active factor
    Patent number: 5294544
    Abstract: The invention comprises a factor having the following characteristics:a) It inhibits granulocyte-macrophage colony and cluster formation;b) It has a molecular weight of about 8 kDa as determined by SDS-PAGE;c) It has a weak anionic charge at pH 7.4 as shown by anion exchange chromatography;d) It has a flattened isoelectric titration curve as shown by anion exchange chromatography; andd) It is a protein.The invention also comprises methods of making and using the factor and compositions comprising the factor.
    Type: Grant
    Filed: May 22, 1992
    Date of Patent: March 15, 1994
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Patrick S. Gentile, Charlie R. Mantel, Hal E. Broxmeyer
  • Method of inhibiting progenitor cell proliferation
    Patent number: 5149544
    Abstract: The invention comprises a factor having the following characteristics:a) It inhibits granulocyte-macrophage colony and cluster formation;b) It has a molecular weight of about 8 kDa as determined by SDS-PAGE;c) It has a weak anionic charge at pH 7.4 as shown by anion exchange chromatography;d) It has a flattened isoelectric titration curve as shown by anion exchange chromatography; ande) It is a protein.The invention also comprises methods of making and using the factor and compositions comprising the factor.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: September 22, 1992
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Patrick S. Gentile, Charlie R. Mantel, Hal E. Broxmeyer