Patents by Inventor Charu Vepari

Charu Vepari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Covalently immobilized protein gradients in three-dimensional porous scaffolds
    Patent number: 9290579
    Abstract: The invention provides a method for forming an immobilized agent gradient within a 3-dimensional porous scaffold. A 3-dimensional scaffold formed from a biocompatible material is provided. The surface of the scaffold and/or the agent is activated so as to allow binding of the agent to the scaffold. The activated scaffold is contacted with a solution containing the agent. Contact with the solution is maintained for a sufficient period of time to allow diffusion of the solution through a portion of the scaffold, thereby forming a desired gradient of the agent through the 3-dimensional scaffold.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: March 22, 2016
    Assignees: Trustees of Tufts College, Massachusetts Institute of Technology
    Inventors: Charu Vepari, David L. Kaplan, Gordana Vunjak-Novakovic
  • COVALENTLY IMMOBILIZED PROTEIN GRADIENTS IN THREE-DIMENSIONAL POROUS SCAFFOLDS
    Publication number: 20130230491
    Abstract: The invention provides a method for forming an immobilized agent gradient within a 3-dimensional porous scaffold. A 3-dimensional scaffold formed from a biocompatible material is provided. The surface of the scaffold and/or the agent is activated so as to allow binding of the agent to the scaffold. The activated scaffold is contacted with a solution containing the agent. Contact with the solution is maintained for a sufficient period of time to allow diffusion of the solution through a portion of the scaffold, thereby forming a desired gradient of the agent through the 3-dimensional scaffold.
    Type: Application
    Filed: February 25, 2013
    Publication date: September 5, 2013
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, TRUSTEES OF TUFTS COLLEGE
    Inventors: Charu Vepari, David L. Kaplan, Gordana Vunjak-Novakovic
  • Covalently immobilized protein gradients in three-dimensional porous scaffolds
    Publication number: 20070212730
    Abstract: The invention provides a method for forming an immobilized agent gradient within a 3-dimensional porous scaffold. A 3-dimensional scaffold formed from a biocompatible material is provided. The surface of the scaffold and/ or the agent is activated so as to allow binding of the agent to the scaffold. The activated scaffold is contacted with a solution containing the agent. Contact with the solution is maintained for a sufficient period of time to allow diffusion of the solution through a portion of the scaffold, thereby forming a desired gradient of the agent through the 3-dimensional scaffold.
    Type: Application
    Filed: April 19, 2006
    Publication date: September 13, 2007
    Applicants: Trustees of Tufts College, Massachusetts Institute of Technology
    Inventors: Charu Vepari, David Kaplan, Gordana Vunjak-Novakovic