Patents by Inventor Chengcheng Jin

Chengcheng Jin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240065234
    Abstract: A welfare-oriented raising house for meat-type ducks, including a raising house, is provided. The raising house is internally provided with a support frame which is of a U-shaped structure and arranged in a length direction of the raising house, a raising net arranged at a top of the support frame, a cleaning and storing mechanism arranged at one end of the support frame for cleaning and storing the raising net, a traction mechanism arranged at the other end of the support frame for the traction of the raising net, blocking mechanisms which are of a zigzag structure and arranged at both sides of the support frame, and tensioning vibration mechanisms arranged at bottoms of the blocking mechanisms and fixedly connected to a side edge of the support frame.
    Type: Application
    Filed: August 24, 2023
    Publication date: February 29, 2024
    Applicant: Anhui Agricultural University
    Inventors: Sihua JIN, Weifeng GAO, Zhaoyu GENG, Lijun JIANG, Chengcheng CAO, Bailing XUE, Zihui ZHU, Xuan ZHOU, Ziting PAN
  • Patent number: 11331269
    Abstract: It has been discovered that lung tumor growth is associated with a dysregulation of the local microbiota, including an increased total bacterial load and reduced bacterial diversity in the airway. In the lungs, commensal bacteria, which are otherwise non-pathogenic and colonize pulmonary tissue at a much lower density in healthy individuals, provoke chronic inflammation and exacerbation of lung cancer through tumor-infiltrating immune cells. Thus, targeting the lung microbiota and its responding immune pathways is useful in treating lung cancer. Disclosed are compositions and methods targeting the lung microbiota and its responding immune pathways in a subject by specific targeting of commensal bacteria in the subject. Typically, the methods involve administering an effective amount of one or more therapeutics such as an antibiotic that reduces the local bacterial load, blocks or depletes tumor-infiltrating immune cells, and/or locally inhibits one or more cytokines or chemokines.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: May 17, 2022
    Assignees: Massachusetts Institute of Technology, The Broad Institute, Inc.
    Inventors: Chengcheng Jin, Georgia Lagoudas, Paul Blainey, Tyler Jacks
  • Publication number: 20200078296
    Abstract: It has been discovered that lung tumor growth is associated with a dysregulation of the local microbiota, including an increased total bacterial load and reduced bacterial diversity in the airway. In the lungs, commensal bacteria, which are otherwise non-pathogenic and colonize pulmonary tissue at a much lower density in healthy individuals, provoke chronic inflammation and exacerbation of lung cancer through tumor-infiltrating immune cells. Thus, targeting the lung microbiota and its responding immune pathways is useful in treating lung cancer. Disclosed are compositions and methods targeting the lung microbiota and its responding immune pathways in a subject by specific targeting of commensal bacteria in the subject. Typically, the methods involve administering an effective amount of one or more therapeutics such as an antibiotic that reduces the local bacterial load, blocks or depletes tumor-infiltrating immune cells, and/or locally inhibits one or more cytokines or chemokines.
    Type: Application
    Filed: June 21, 2019
    Publication date: March 12, 2020
    Inventors: Chengcheng Jin, Georgia Lagoudas, Paul Blainey, Tyler Jacks
  • Publication number: 20140377278
    Abstract: The present invention relates to the discovery that the disruption of inflammasome function leads to an altered microbiota that affects the development and progression of inflammatory diseases and disorders. Thus, the invention relates to compositions and methods for detecting and determining the relative proportions of the constituents of a subject's microbiota, methods of modifying an altered microbiota population in a subject, and compositions and methods for treating inflammatory diseases and disorders in a subject in need thereof.
    Type: Application
    Filed: April 16, 2012
    Publication date: December 25, 2014
    Applicant: Yale University
    Inventors: Eran Elinav, Richard A. Flavell, Till Strowig, Jorge H. Mejia, Chengcheng Jin