Patents by Inventor Chi Fai Chan

Chi Fai Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10787465
    Abstract: Provided herein are lanthanide complexes that exhibit specific subcellular localization to primary cilium. The lanthanide complexes provided herein are useful for imaging, tagging, and pull down of binding targets located in primary cilium.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: September 29, 2020
    Assignee: New Life Medicine Technology Company Limited
    Inventors: Ka Leung Wong, Hongguang Li, Chi Fai Chan, Rongfeng Lan
  • Publication number: 20190127393
    Abstract: Provided herein are lanthanide complexes that exhibit specific subcellular localization to primary cilium. The lanthanide complexes provided herein are useful for imaging, tagging, and pull down of binding targets located in primary cilium.
    Type: Application
    Filed: October 31, 2018
    Publication date: May 2, 2019
    Inventors: Ka Leung WONG, Hongguang LI, Chi Fai CHAN, Rongfeng LAN
  • Patent number: 10183956
    Abstract: The present invention relates to a water-soluble, simple, stable tris(N-(tert-butyl)acetamide) cyclen-based europium complex HGEu001 which exhibits the specific subcellular localization in the primary cilium with a quantum yield as high as 10% in water and a lifetime of 0.56 ms lifetime. In particular, the present invention provides simplicity of the design and synthesis of a complex. Comprehensive studies were performed in numerous cell lines, such as HeLa, SN-K-SH and MRC5; the motif structure, HGEu002, has also been synthesized as the negative control for in vitro imaging studies. The two photon in vitro imaging were done in three dimensions to emphasize on the specific localization in primary cilium of HGEu001. This is one of the very limited examples for direct primary cilium imaging.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: January 22, 2019
    Assignee: New Life Medicine Technology Company Limited
    Inventors: Ka Leung Wong, Hongguang Li, Chi Fai Chan, Rongfeng Lan
  • Publication number: 20170342090
    Abstract: The present invention relates to a water-soluble, simple, stable tris(N-(tert-butyl)acetamide) cyclen-based europium complex HGEu001 which exhibits the specific subcellular localization in the primary cilium with a quantum yield as high as 10% in water and a lifetime of 0.56 ms lifetime. In particular, the present invention provides simplicity of the design and synthesis of a complex. Comprehensive studies were performed in numerous cell lines, such as HeLa, SN-K-SH and MRC5; the motif structure, HGEu002, has also been synthesized as the negative control for in vitro imaging studies. The two photon in vitro imaging were done in three dimensions to emphasize on the specific localization in primary cilium of HGEu001. This is one of the very limited examples for direct primary cilium imaging.
    Type: Application
    Filed: May 25, 2017
    Publication date: November 30, 2017
    Inventors: Ka Leung WONG, Hongguang LI, Chi Fai CHAN, Rongfeng LAN
  • Patent number: 8342977
    Abstract: The amplitude of a swing powered by an electric motor is controlled by detecting a peak voltage induced in the motor coil by the swing motion when the motor is not being powered and comparing the detected voltage with a one of a set of pre-measured reference values of peak voltages obtained at corresponding amplitude settings to provide a signal to a motor controller which adjusts the power supplied to the motor to bring the swing amplitude to. The motor controller supplies a PWM signal voltage to power the motor and adjusts the voltage on-time to bring or restore the swing to the selected amplitude.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: January 1, 2013
    Assignee: Max Technology Capital Ltd
    Inventors: Bernie Ting, Yau Choi Tse, Chi Fai Chan
  • Publication number: 20100298058
    Abstract: The amplitude of a swing powered by an electric motor is controlled by detecting a peak voltage induced in the motor coil by the swing motion when the motor is not being powered and comparing the detected voltage with a one of a set of pre-measured reference values of peak voltages obtained at corresponding amplitude settings to provide a signal to a motor controller which adjusts the power supplied to the motor to bring the swing amplitude to. The motor controller supplies a PWM signal voltage to power the motor and adjusts the voltage on-time to bring or restore the swing to the selected amplitude.
    Type: Application
    Filed: April 23, 2008
    Publication date: November 25, 2010
    Inventors: Bernie Ting, Yau Choi Tse, Chi Fai Chan
  • Patent number: 7289801
    Abstract: A system and method for invoking one or more features of a wireless device when a signal strength of a channel approaches or drops below an RSSI threshold of the channel is disclosed. An embodiment of the invention includes the steps of (1) obtaining the RSSI threshold for the channel; (2) monitoring the signal strength during an operation mode of the wireless device; and (3) invoking the feature when the signal strength approaches a predetermined limit of the RSSI threshold. In an implementation on a cordless telephone, the feature can include playing a warning, switching to a different channel, or returning a telephone line to an idle state.
    Type: Grant
    Filed: January 8, 2003
    Date of Patent: October 30, 2007
    Assignee: VTech Telecommunications Limited
    Inventors: Chi Fai Chan, Hei Ming Tsang, Wai-Hung Leung
  • Publication number: 20040203700
    Abstract: A system and method for invoking one or more features of a wireless device when a signal strength of a channel approaches or drops below an RSSI threshold of the channel is disclosed. An embodiment of the invention includes the steps of (1) obtaining the RSSI threshold for the channel; (2) monitoring the signal strength during an operation mode of the wireless device; and (3) invoking the feature when the signal strength approaches a predetermined limit of the RSSI threshold. In an implementation on a cordless telephone, the feature can include playing a warning, switching to a different channel, or returning a telephone line to an idle state.
    Type: Application
    Filed: January 8, 2003
    Publication date: October 14, 2004
    Inventors: Chi Fai Chan, Hei Ming Tsang, Wai-Hung Leung
  • Publication number: 20040204138
    Abstract: A system and method transferring a data file is disclosed. One embodiment of the invention is a cable that is configured to transfer a data file from a data source to a handset of a cordless telephone. Another embodiment of the invention is a handset of a cordless telephone that is configured to receive a data file and to play the data file during an operation mode associated with the data file. The preferred data file is an animation file.
    Type: Application
    Filed: January 8, 2003
    Publication date: October 14, 2004
    Inventors: Wing Nam Tse, Chi Fai Chan
  • Publication number: 20040192409
    Abstract: A method for managing power in a cordless telephone is disclosed. The method includes an avoidance of operating all components of the cordless telephone concurrently. In one embodiment, a charging process of the handset is disabled during an RF transmission process between the base station and the handset.
    Type: Application
    Filed: January 8, 2003
    Publication date: September 30, 2004
    Inventors: Chi Fai Chan, Kwok Hing Ngai
  • Publication number: 20030005705
    Abstract: A multi-axial thermal isolator device for isolating structures formed of differing materials. The device is rigidly attached to both structures and is capable of movement as the result of relative thermal expansion of the structures. The device has a substantially C or Z-shaped configuration with a curved portion forming an angle &thgr; in the range of about 0-10 degrees. The device provides a means for thermal decay between adjacent structures when the parts are subjected to large changes in temperature.
    Type: Application
    Filed: July 5, 2001
    Publication date: January 9, 2003
    Applicant: Honeywell International, Inc.
    Inventors: Chi-Fai Chan, Ly D. Nguyen, Anton Liu