Abstract: High affinity CD47 reagents are provided, which (i) comprise at least one amino acid change relative to the wild-type protein; and (ii) have an increased affinity for a SIRP? relative to the wild-type protein. Compositions and methods are provided for modulating phagocytosis in a mammal by administering a therapeutic dose of a pharmaceutical composition comprising a high affinity CD47 reagent, which blocks the physiological binding interaction between SIRP? and a ligand, e.g., native CD47.

Abstract: An antenna device includes a first dielectric substrate, a first radiator disposed on the first dielectric substrate, a second dielectric substrate disposed on the first radiator, a second radiator disposed between the first dielectric substrate and the second dielectric substrate, a main radiator, disposed on the second dielectric substrate, and a modulation structure located between a first radiation portion of the first radiator and a second radiation portion of the second radiator. The first radiation portion, the modulation structure, and the second radiation portion are located in a central area.

Abstract: Modified polysaccharides and crosslinked modified polysaccharide compositions are described. Methods of using the crosslinked modified polysaccharide compositions to deliver proteins, oligonucleotides, or pharmaceutical agents are also disclosed.

Abstract: One or more circuit arrangements and techniques for modeling are provided. In some embodiments, a circuit arrangement includes at least one of a first current source, a second current source, a first diode, a second diode, and a switching component. In some embodiments, the switching component includes a bipolar junction transistor (BJT). In some embodiments, the circuit arrangement is integrated into a metal oxide semiconductor (MOS) device. When the circuit arrangement is integrated into a MOS device, at least one of a substrate current leakage, a junction breakdown, or a diode reverse recovery (DRR) effect is predictable for the MOS device.

Abstract: In some embodiments, in a method, a netlist is received. The netlist comprises a subcircuit that comprises a device and a rule check module. The rule check module specifies a plurality of terminals of the device subject to an operating space, and at least one parameter that controls a non-rectangular boundary of the operating space. The netlist is simulated to obtain simulation data associated with the terminals of the device. The operating space that has the non-rectangular boundary is formed by using the at least one parameter. The simulation data is checked against the operating space. A situation in which the checked simulation data does not fall within the operating space is reflected.

Abstract: In some embodiments, in a method, a netlist is received. The netlist comprises a subcircuit that comprises a device and a rule check module. The rule check module specifies a plurality of terminals of the device subject to an operating space, and at least one parameter that controls a non-rectangular boundary of the operating space. The netlist is simulated to obtain simulation data associated with the terminals of the device. The operating space that has the non-rectangular boundary is formed by using the at least one parameter. The simulation data is checked against the operating space. A situation in which the checked simulation data does not fall within the operating space is reflected.

Abstract: One or more circuit arrangements and techniques for modeling are provided. In some embodiments, a circuit arrangement includes at least one of a first current source, a second current source, a first diode, a second diode, and a switching component. In some embodiments, the switching component includes a bipolar junction transistor (BJT). In some embodiments, the circuit arrangement is integrated into a metal oxide semiconductor (MOS) device. When the circuit arrangement is integrated into a MOS device, at least one of a substrate current leakage, a junction breakdown, or a diode reverse recovery (DRR) effect is predictable for the MOS device.

Abstract: A conductive structure for a panel is formed on a plate and includes a first metal layer, a nitride layer, and a second metal layer. The first metal layer is located on the plate and has a first side surface and a lower surface connected to the first side surface, while the lower surface makes contact with the plate. The first metal layer contains molybdenum. The nitride layer is located on the first metal layer and has a second side surface. The nitride layer contains molybdenum. The second metal layer is located on the nitride layer and has a third side surface. The second side surface is adjacent to the first side surface and the third side surface, to form an inclined surface. An included angle between the inclined surface and the lower surface is between 20 degrees and 75 degrees.

Abstract: Modified polysaccharides and crosslinked modified polysaccharide compositions are described. Methods of using the crosslinked modified polysaccharide compositions to deliver proteins, oligonucleotides, or pharmaceutical agents are also disclosed.

Abstract: A process for the encapsulation of liquid particles within nanometer thick polymer shells utilizes an interfacial free radical alternating copolymerization process. Encapsulating a liquid material includes providing a mixture comprising the liquid material to be encapsulated, a hydrophobic monomer in a non-polar solution and a hydrophilic monomer in a polar solution. The liquid material is compatible in either the polar solution or the non-polar solution. The polar solution and the non-polar solution are not miscible in each other. The mixture is homogenized to form an emulsion, and then polymerized by an initiator which initiates an interfacial free radical alternating copolymerization process. The copolymerization process is optimally constrained to proceed only at the hydrophobic and hydrophilic interface thus forming a polymer around the liquid material.

Abstract: A process for the encapsulation of liquid particles within nanometer thick polymer shells utilizes an interfacial free radical alternating copolymerization process. Encapsulating a liquid material includes providing a mixture comprising the liquid material to be encapsulated, a hydrophobic monomer in a non-polar solution and a hydrophilic monomer in a polar solution. The liquid material is compatible in either the polar solution or the non-polar solution. The polar solution and the non-polar solution are not miscible in each other. The mixture is homogenized to form an emulsion, and then polymerized by an initiator which initiates an interfacial free radical alternating copolymerization process. The copolymerization process is optimally constrained to proceed only at the hydrophobic and hydrophilic interface thus forming a polymer around the liquid material.