Abstract: A pharmaceutical composition containing a mixed polymeric micelle and a drug enclosed in the micelle, in which the mixed polymeric micelle, 1 to 1000 nm in size, includes an amphiphilic block copolymer and a lipopolymer. Also disclosed are preparation of the pharmaceutical composition and use thereof for treating cancer.

Abstract: An electronic substrate and an electronic device are provided. The electronic substrate includes a base, a conductive electrode, and a first layer. The conductive electrode and the first layer are disposed on the base, the first layer surrounds the conductive electrode and overlaps an edge portion of the conductive electrode. In a cross-sectional view, the first layer is divided into a first part and a second part, the conductive electrode is located between the first part and the second part, and a width of the first part is different from a width of the second part.

Abstract: An electronic substrate and an electronic device are provided. The electronic substrate includes a base, a protruding portion, and a bonding pad. The protruding portion and the bonding pad are disposed on the base. The bonding pad is not overlapped with a boundary of the protruding portion.

Abstract: A method for enhancing an expression of insulin like growth factor 1 receptor in an umbilical cord mesenchymal stem cell is provided. The method includes culturing the umbilical cord mesenchymal stem cell expressing insulin-like growth factor 1 receptor in a medium containing platelet-derived growth factor BB (PDGF-BB) to enhance the expression of insulin like growth factor 1 receptor in the umbilical cord mesenchymal stem cell.

Abstract: A method for enhancing an expression of insulin like growth factor 1 receptor in a mesenchymal stem cell is provided. The method includes culturing the mesenchymal stem cell expressing insulin-like growth factor 1 receptor in a medium containing platelet-derived growth factor BB (PDGF-BB) to enhance the expression of insulin like growth factor 1 receptor in the mesenchymal stem cell.

Abstract: A flexible electronic device is provided in this disclosure. The flexible electronic device includes a base layer, an electronic unit, and a cover layer. The electronic unit is disposed on the base layer, and the cover layer is disposed on the electronic unit. The base layer has a thickness T1 and a Young's modulus E1, and the cover layer has a thickness T2 and a Young's modulus E2, wherein the thickness T1, the thickness T2, the Young's modulus E1, and the Young's modulus E2 comply with following expression: E2/E1?156.21×(T2/T1)?4.28.

Abstract: An electronic substrate and an electronic device are provided. The electronic substrate includes a base, a protruding portion, and a bonding pad. The protruding portion and the bonding pad are disposed on the base. The bonding pad is not overlapped with a boundary of the protruding portion.

Abstract: A method for treating a multiple sclerosis is provided. The method includes administering a composition containing a plurality of mesenchymal stem cells to a subject in need for a treatment of the multiple sclerosis, in which each of the mesenchymal stem cells expresses insulin-like growth factor 1 receptors.

Abstract: An electronic device which is capable of being bent in a first direction and includes a plurality of light-emitting units and a plurality of conductive patterns overlapping with at least a portion of the plurality of light-emitting units and extending in a second direction. The first direction and the second direction have an angle ? of not greater than 30 degrees.

Abstract: The present disclosure provides methods for modulating tolerance to opiates, opioids or opioid analgesics and/or treating acute and chronic pain and/or decreasing opiate or opioid-induced side effects. Also provided is a combination comprising a therapeutically effective amount, or a sub-therapeutically effective amount, of opiate, opioid or opioid analgesic and a therapeutically effective amount of a cystine/glutamate antiporter system xc? inhibitor.

Abstract: Moving an article after a material, such as a hot-melt adhesive, has been applied to a surface of the article is accomplished with an article transfer apparatus. The apparatus is comprised of a belt having a plurality of apertures extending there through that are effective to communicate a vacuum pressure from an inner surface of the belt to a contacting surface of the belt. The vacuum pressure secures and adheres the article to the contacting surface of the belt as the belt conveys the article. The vacuum pressure is distributed along the inner surface of the belt by a vacuum chamber, which is between a compression roller and a second roller.

Abstract: An immunomagnetic nanocapsule includes a core, a shell and an outer layer. The shell is formed by a complex, and the complex is fabricated by a combination of fucoidan, oxidized dextran, and a plurality of superparamagnetic iron oxide nanoparticles via a hydrophobic interaction. The core is encapsulated in the shell. The outer layer includes at least one antibody immobilized to outside of the shell to form the outer layer, wherein the antibody is an immune checkpoint inhibitor and/or a T cell expansion antibody.

Abstract: A method for enhancing an expression of insulin like growth factor 1 receptor in a mesenchymal stem cell is provided. The method includes culturing the mesenchymal stem cell expressing insulin-like growth factor 1 receptor in a medium containing platelet-derived growth factor BB (PDGF-BB) to enhance the expression of insulin like growth factor 1 receptor in the mesenchymal stem cell.

Abstract: A method for enhancing an insulin like growth factor 1 receptor expression of a mesenchymal stem cell is provided. The method includes culturing a plurality of mesenchymal stem cells expressing insulin-like growth factor 1 receptors in media containing human cord blood serum to enhance the insulin like growth factor 1 receptor expression of the mesenchymal stem cells.

Abstract: The invention surprisingly found that agents that inhibit system xc? provide the therapeutic intervention in substance-related and addictive disorders and the treatment and/or prevention in substance-mediated brain damage and confirms that system xc? is a promising therapeutic target for substance-induced addiction and brain damage.

Abstract: A dot projector with automatic power control includes a housing covering a substrate with an installing space and a platform therein, an automatic power control integrated circuit, a photodiode and a reflector disposed under the platform of the housing, a collimator disposed in the installing space of the housing and a diffractive optical element bonded on the platform of the housing. Whereby a laser diode emits a laser light to the reflector for the laser light to be reflected perpendicularly through the collimator to the diffractive optical element; then the diffractive optical element produces a plurality of light spots and the a stray light is also produced from the laser light. The photodiode of the automatic power control integrated circuit then detects the stray light and produces a feedback signal transmitted back to the laser diode for adjustment of the laser emission power in order to control the light spots produced by the diffractive optical element.

Abstract: A method for treating a multiple sclerosis is provided. The method includes administering a composition containing a plurality of mesenchymal stem cells to a subject in need for a treatment of the multiple sclerosis, in which each of the mesenchymal stem cells expresses insulin-like growth factor 1 receptors.

Abstract: A laser module package with dual colors and multi-dies mainly includes a first PCB arranged in long shape and electrically connected to a plurality of first dies, a second PCB arranged in long shape and electrically connected to a plurality of second dies, a plurality of first collimators correspondingly disposed in a plurality of first openings, and a plurality of second collimators correspondingly disposed in a plurality of second openings. A plurality of first reflectors correspondingly reflects laser beams emitted from the first dies to the first collimators and a plurality of second reflectors correspondingly reflects laser beams emitted from the second dies to the second collimators; or having a plurality of first metal pieces fixing corresponding first dies for the laser beams emitted therefrom to go through the corresponding first collimators and a plurality of second metal pieces fixing corresponding second dies for the laser beams emitted therefrom to go through the corresponding second collimators.

Abstract: An immunomagnetic nanocapsule includes a core, a shell and an outer layer. The shell is formed by a complex, and the complex is fabricated by a combination of fucoidan, oxidized dextran, and a plurality of superparamagnetic iron oxide nanoparticles via a hydrophobic interaction. The core is encapsulated in the shell. The outer layer includes at least one antibody immobilized to outside of the shell to form the outer layer, wherein the antibody is an immune checkpoint inhibitor and/or a T cell expansion antibody.

Abstract: The invention surprisingly found that agents that inhibit system xc? provide the therapeutic intervention in substance-related and addictive disorders and the treatment and/or prevention in substance-mediated brain damage and confirms that system xc? is a promising therapeutic target for substance-induced addiction and brain damage.