Abstract: ALK abnormalities are widely found in a variety of pediatric malignant solid tumors, and ALK inhibitors against ALK abnormalities are considered an important target in the development of treatment in the field of pediatric oncology. According to the present invention, it is possible to provide a pharmaceutical composition for the treatment of childhood cancer with an ALK abnormality, with a novel dosage and administration, comprising alectinib or a salt thereof, and to be used in the treatment of cancer in children under the age of 2.

Abstract: A bin-module based automated storage and retrieval system (ASRS) includes a plurality of storage shelves, each removably supporting a plurality of bin modules. Each bin module includes multiple bins. The system also includes a collection shelf configured to removably support bin modules. The system further includes a dolly including: (a) a dolly frame, (b) a drive module configured to propel the dolly, and (c) an actuator configured to move a coupler to couple to the bin module supported in one of the plurality of storage shelves when the dolly is positioned adjacent to said storage shelf, the actuator being further configured to remove said bin module from said storage shelf to the dolly frame, and to move said bin module from the dolly frame to the collection shelf when the dolly is positioned adjacent to the collection shelf.

Abstract: A bin-module based automated storage and retrieval system (ASRS) includes a plurality of storage shelves, each removably supporting a plurality of bin modules. Each bin module includes multiple bins. The system also includes a collection shelf configured to removably support bin modules. The system further includes a dolly including: (a) a dolly frame, (b) a drive module configured to propel the dolly, and (c) an actuator configured to move a coupler to couple to the bin module supported in one of the plurality of storage shelves when the dolly is positioned adjacent to said storage shelf the actuator being further configured to remove said bin module from said storage shelf to the dolly frame, and to move said bin module from the dolly frame to the collection shelf when the dolly is positioned adjacent to the collection shelf.

Abstract: An optical packet network system of a ring type, capable of preventing degradation of an optical signal, can be implemented by providing a mechanism relatively simple in structure, capable of erasing light noise if the optical packet signal does not exists. In the optical packet network system made up by interconnecting respective nodes adjacent to each other, and connecting a sending source of an optical packet signal to a ring, a light noise removal function block is provided between the respective nodes adjacent to each other.

Abstract: An optical communication apparatus includes an erbium-doped optical fiber amplifier for amplifying a modulated optical signal, wherein a light which is not modulated is inputted to the erbium-doped optical fiber amplifier together with the optical signal.

Abstract: The present invention makes improvements in a mobile communication system that performs a communication via a communication network provided in a mobile body to execute a data transfer. The present system comprises a plurality of nodes, a path control device which receives data from the nodes respectively, selects a path for the data transfer on the communication network, and outputs the data, first optical fibers which connect each of the nodes and the path control device and transfer the data, and second optical fibers provided in parallel with the first optical fibers. In the present system, the path control device communicates with the node via the second optical fiber when a failure occurs in the first optical fiber.

Abstract: A clock reproducing apparatus includes a clock reproducing circuit having: a gated oscillator having an oscillating circuit of two routes; and a frequency control circuit for comparing a phase of an output of the gated oscillator with a phase of a reference clock, and supplying a phase control signal to the gated oscillator based on the comparison result so as to set a delay time, input data is input to a reset input terminal of the gated oscillator, and different route of the two routes of the oscillating circuit operates depending on a case where the input data is “H” and a case where the input data is “L”.

Abstract: There is provided an A/D converter capable of changing specification and function of the A/D converter with the use of a programmable circuit by combining comparators with the programmable circuit. The A/D converter comprises a parallel-connected comparison circuit including a plurality of comparators, an analog signal being inputted to one of input terminals of the respective comparators while respective predetermined reference voltages being inputted to the other of the input terminals of the respective comparators, and a digital processing circuit for receiving output signals from the parallel-connected comparison circuit, and executing predetermined digital processing as set on the basis of a program.

Abstract: In a forward error correction method and a forward error correction addition apparatus, error correction is performed on the basis of data, to which forward error correction code is added, transmitted through a network to output decoded data. The data transmitted through the network includes information bits represented by an information bit matrix with n rows and m columns (n, m are natural numbers), and redundancy bits represented by an odd number of redundancy information bit rows and an odd number of redundancy information bit columns based on the information bit matrix, which are provided in the row direction and in the column direction of the information bit matrix respectively. The redundancy bits are the forward error correction code.

Abstract: A clock reproducing apparatus includes a clock reproducing circuit having: a gated oscillator having an oscillating circuit of two routes; and a frequency control circuit for comparing a phase of an output of the gated oscillator with a phase of a reference clock, and supplying a phase control signal to the gated oscillator based on the comparison result so as to set a delay time, input data is input to a reset input terminal of the gated oscillator, and different route of the two routes of the oscillating circuit operates depending on a case where the input data is “H” and a case where the input data is “L”.

Abstract: An optical waveform shaping device includes a first waveguide portion, formed on a substrate, for transmitting the optical signal and simultaneously absorbing a portion of the optical signal, which has a signal level equal to or smaller than a predetermined value, so as to shape the optical signal; and a second waveguide portion, formed on the substrate, for transmitting the optical signal, which was transmitted through the first waveguide portion, and simultaneously amplifying the optical signal. The first waveguide portion may be formed using a saturable absorber. A first electrode for supplying electric current to the first waveguide portion so that the first waveguide portion is provided with a function of absorbing the optical signal; and a second electrode for supplying electric current to the second waveguide portion so that the second waveguide portion is provided with a function of amplifying the optical signal may also be provided.

Abstract: Disclosed is a repeater including: a recognizing unit to recognize a destination address of an optical packet from the optical packet which includes the destination address assigned in unit of bit and a bit indicating whether or not a plurality of destination addresses are assigned; an optical splitting unit to split the optical packet into a plurality of optical packets; and selecting units to select transmission channels for the split optical packets on the basis of recognition results by the recognizing units, respectively.

Abstract: A variable light signal delay apparatus includes a first delay optical fiber, a second delay optical fiber having a length different from the first delay optical fiber, and an optical switch having two input ports, two output ports, and paths, through which a light signal propagates, provided between the first delay optical fiber and the second delay optical fiber, in which a light signal input from at least one of the input ports propagated through either the first delay optical fiber or the second delay optical fiber or through neither the first delay optical fiber nor the second delay optical fiber to be output from a desired first output port.

Abstract: An object of this invention is to realize a pulse pattern generating apparatus that outputs a test signal of high waveform quality even when the shape of an eye pattern is changed. This invention is an improvement of a pulse pattern generating apparatus that generates a test signal of a predetermined pattern by using plural digital-analog converters and outputs the test signal to a test subject.

Abstract: In an optical packet processing apparatus, an optical coupler joins optical packets transmitted through a plurality of input side optical transmission lines and outputs the joined optical packets to an output side optical transmission line. The optical packet processing apparatus has delay sections for delaying desired optical packets for each input side optical transmission lines. Delay times of the delay sections are different by one optical packet time period, while a minimum delay time thereof is the optical packet time period or more.

Abstract: A light modulating apparatus which is to be used in a transmission system using wavelength division multiplexing has: a signal generating section for producing a transmission signal and the like; a first light modulating section for modulating light emitted from a light source, on the basis of the transmission signal; a variable phase shifter which changes a phase of a light quantity control signal; a second light modulating section for modulating a light signal emitted from the first light modulating section, on the basis of an output of the variable phase shifter; a branching section for branching a light signal emitted from the second light modulating section, into an output light signal and an electric signal; and an analysis controlling section for sampling the electric signal, controlling the variable phase shifter on the basis of sampled data, and adjusting a timing of the modulation in the second light modulating section.

Abstract: An optical switch changes over transmission paths of an optical signal by a refractive index change. The optical switch has an optical waveguide layer having an optical waveguide whose output path of an optical signal branches into two, and reflection diffusing ditches which are provided in a portion outside the optical waveguide in the optical waveguide layer, wherein the portion is closed to a branch portion of the optical waveguides. The reflection diffusing ditches extend in a direction crossing a traveling direction of the optical signal.

Abstract: An optical switch in which the adverse effect of heating can be restrained is realized.

Abstract: An optical router for selecting optical paths for optical signals and outputting the optical signals. The optical router includes an optical delay device to delay the optical signals containing routing information in a header. An optical switch having input ports' and output ports receives optical outputs that are input from the optical delay device and outputs the optical signals. An optical-electrical conversion device converts the optical signals to electrical signals. A memory stores paths control information. A controller finds the path control information according to routing information output from the optical-electrical conversion device, determines destinations of the optical signal, and selects and assigns an input port in sequence from at least one input port having an output request to the output ports according to results of sorting a plurality of the output ports in ascending order of a number of output requests from the input ports.

Abstract: A clock reproducing apparatus includes a clock reproducing circuit having: a gated oscillator having an oscillating circuit of two routes; and a frequency control circuit for comparing a phase of an output of the gated oscillator with a phase of a reference clock, and supplying a phase control signal to the gated oscillator based on the comparison result so as to set a delay time, input data is input to a reset input terminal of the gated oscillator, and different route of the two routes of the oscillating circuit operates depending on a case where the input data is “H” and a case where the input data is “L”.