Patents by Inventor Chien-Tien Chen

Chien-Tien Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11937932
    Abstract: An acute kidney injury predicting system and a method thereof are proposed. A processor reads the data to be tested, the detection data, the machine learning algorithm and the risk probability comparison table from a main memory. The processor trains the detection data according to the machine learning algorithm to generate an acute kidney injury prediction model, and inputs the data to be tested into the acute kidney injury prediction model to generate an acute kidney injury characteristic risk probability and a data sequence table. The data sequence table lists the data to be tested in sequence according to a proportion of each of the data to be tested in the acute kidney injury characteristics. The processor selects one of the medical treatment data from the risk probability comparison table according to the acute kidney injury characteristic risk probability.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: March 26, 2024
    Assignees: TAICHUNG VETERANS GENERAL HOSPITAL, TUNGHAI UNIVERSITY
    Inventors: Chieh-Liang Wu, Chun-Te Huang, Cheng-Hsu Chen, Tsai-Jung Wang, Kai-Chih Pai, Chun-Ming Lai, Min-Shian Wang, Ruey-Kai Sheu, Lun-Chi Chen, Yan-Nan Lin, Chien-Lun Liao, Ta-Chun Hung, Chien-Chung Huang, Chia-Tien Hsu, Shang-Feng Tsai
  • Publication number: 20220372073
    Abstract: A method for preparing a cyclopeptide and a cyclopeptide preparing by the method are disclosed. The method includes the following steps: (a) providing compounds represented by formulas (I-1) and (I-4); (b) performing a reaction between the compounds of formulas (I-1) and (I-4) to obtain a compound represented by formula (I-5); (c) performing a reaction between the compound of formula (I-5) and the compound represented by formula (I-6) to obtain a compound represented by formula (I-7); (d) performing a cyclization reaction of the compound of formula (I-7) with a catalyst of formula (II) and deprotection to obtain a compound represented by formula (III), wherein the compounds of formulas (I-1), (I-4) to (I-7), (III) and the catalyst of formula (II) are as defined in the specification.
    Type: Application
    Filed: July 14, 2022
    Publication date: November 24, 2022
    Inventors: Chien-Tien CHEN, Shiue-Shien WENG
  • Patent number: 11485756
    Abstract: A method for preparing a cyclopeptide and a cyclopeptide preparing by the method are disclosed. The method includes the following steps: (A) providing compounds represented by the following formulas (I-1) and (I-2): wherein, G, Ra, Rb, Rc, Rd, and Re are defined in the specification; (B) performing a reaction between the compounds of formulas (I-1) and (I-2) to obtain a compound represented by the following formula (I-3): and (C) performing a cyclization reaction of the compound of formula (I-3) with a catalyst of formula (II) and deprotection to obtain a compound represented by the following formula (III): wherein, G?, Q, M, L1, L2, m, y, and z are defined in the specification.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: November 1, 2022
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Chien-Tien Chen, Shiue-Shien Weng
  • Patent number: 11407692
    Abstract: A method for oxidative cleavage of a compound with an unsaturated double bond is provided.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: August 9, 2022
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Chien-Tien Chen, Yi-Ya Liao, Ya-Pei Chen
  • Publication number: 20220144976
    Abstract: A block copolymer is disclosed. The block copolymer has a structure of formula (V) below: [D]x-[E]y-[F]z??(V) wherein D, E, and F are each independently a compound of formula (VI) below, and D, E, and F are different from each other; and x, y, and z are each independently an integer from 1 to 40; wherein A2 is O or S; R7 is H or a C1-6 alkyl; and R8 is a C1-12 alkyl, (CH2)qN(R11)2, CH2(CH2OCH2)rCH2N(R12)2, or CH2(CH2OCH2)sCH2OR13, wherein R11, R12, and R13 are each independently a C1-6 alkyl; and q, r, and s are each independently an integer from 1 to 10.
    Type: Application
    Filed: January 27, 2022
    Publication date: May 12, 2022
    Inventors: Chien-Tien CHEN, Yi-Ya LIAO
  • Patent number: 11279776
    Abstract: A block copolymer and a method for preparing the same are disclosed. The method comprises the following steps: (A) mixing a compound of formula (I), a catalyst of formula (II), and a first solvent to obtain a first mixture; (B) adding a first monomer into the first mixture for reaction to obtain a second mixture; and (C) adding a second monomer into the second mixture for reaction to obtain a third mixture; wherein the compound of formula (I) and the catalyst of formula (II) are as defined in the specification.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: March 22, 2022
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Chien-Tien Chen, Yi-Ya Liao
  • Publication number: 20210230222
    Abstract: A method for preparing a cyclopeptide and a cyclopeptide preparing by the method are disclosed. The method includes the following steps: (A) providing compounds represented by the following formulas (I-1) and (I-2): wherein, G, Ra, Rb, Rc, Rd, and Re are defined in the specification; (B) performing a reaction between the compounds of formulas (I-1) and (I-2) to obtain a compound represented by the following formula (I-3): and (C) performing a cyclization reaction of the compound of formula (I-3) with a catalyst of formula (II) and deprotection to obtain a compound represented by the following formula (III): wherein, G?, Q, M, L1, L2, m, y, and z are defined in the specification.
    Type: Application
    Filed: April 28, 2020
    Publication date: July 29, 2021
    Inventors: Chien-Tien CHEN, Shiue-Shien WENG
  • Publication number: 20210206702
    Abstract: A method for oxidative cleavage of a compound with an unsaturated double bond is provided.
    Type: Application
    Filed: April 28, 2020
    Publication date: July 8, 2021
    Inventors: Chien-Tien CHEN, Yi-Ya LIAO, Ya-Pei CHEN
  • Patent number: 11053330
    Abstract: An esterification method of a copolymer is disclosed. The esterification method includes the steps of: (A) mixing a copolymer having a carboxylic acid group, an alcohol or an aminoalcohol compound, a catalyst of formula (I), and a first solvent to obtain a first mixture; (B) reacting the first mixture at a predetermined temperature to obtain a second mixture; and (C) adding the second mixture into a second solvent; wherein the catalyst of formula (I) is shown below: [M(O)a]m+Xbn???(I) wherein M, X, a, b, in, and n are defined in the specification.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: July 6, 2021
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Chien-Tien Chen, Yi-Ya Liao
  • Patent number: 10851134
    Abstract: A method for preparing a cyclopeptide, which includes the following steps: (A) providing compounds represented by the following formulas (II-1) or (II?-1) and (II-2); (B) performing a reaction between the compounds of formulas (II-1) or (II?-1) and (II-2), to obtain a compound represented by the following formula (II-3) and (II?-3), respectively; (C) performing a reaction between the compound of formula (II-3) or (II?-3) and a compound represented by the following formula (II-4) or (II?-4), respectively, is performed, to obtain a compound represented by the following formula (II-5), and (II?-5), respectively; (D) performing a cyclization reaction of the compound of formula (II-5) or (II?-5) with a catalyst of formula (III), to obtain a compound represented by the following formula (I) or (I?), respectively. The formulas (I), (I?), (II-1) to (II-5), (II?-1) to (II?-5) and (III) are shown in the specification.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: December 1, 2020
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventor: Chien-Tien Chen
  • Publication number: 20200339632
    Abstract: A method for preparing a cyclopeptide, which includes the following steps: (A) providing compounds represented by the following formulas (II-1) or (II?-1) and (II-2); (B) performing a reaction between the compounds of formulas (II-1) or (II?-1) and (II-2), to obtain a compound represented by the following formula (II-3) and (II?-3), respectively; (C) performing a reaction between the compound of formula (II-3) or (II?-3) and a compound represented by the following formula (II-4) or (II?-4), respectively, is performed, to obtain a compound represented by the following formula (II-5), and (II?-5), respectively; (D) performing a cyclization reaction of the compound of formula (II-5) or (II?-5) with a catalyst of formula (III), to obtain a compound represented by the following formula (I) or (I?), respectively. The formulas (I), (I?), (II-1) to (II-5), (II?-1) to (II?-5) and (III) are shown in the specification.
    Type: Application
    Filed: July 10, 2020
    Publication date: October 29, 2020
    Inventor: Chien-Tien CHEN
  • Patent number: 10745444
    Abstract: A cyclopeptide is disclosed, which is represented by the following formula (I) or (I?): wherein R1 is defined in the specification. In addition, a pharmaceutical or cosmetic composition comprising the same and a method for preparing the same are also disclosed.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: August 18, 2020
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventor: Chien-Tien Chen
  • Publication number: 20200095348
    Abstract: An esterification method of a copolymer is disclosed. The esterification method includes the steps of: (A) mixing a copolymer having a carboxylic acid group, an alcohol or an aminoalcohol compound, a catalyst of formula (I), and a first solvent to obtain a first mixture; (B) reacting the first mixture at a predetermined temperature to obtain a second mixture; and (C) adding the second mixture into a second solvent; wherein the catalyst of formula (I) is shown below: [M(O)a]m+Xbn+??(I) wherein M, X, a, b, in, and n are defined in the specification.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 26, 2020
    Inventors: Chien-Tien CHEN, Yi-Ya LIAO
  • Publication number: 20200095363
    Abstract: A block copolymer and a method for preparing the same are disclosed. The method comprises the following steps: (A) mixing a compound of formula (I), a catalyst of formula (II), and a first solvent to obtain a first mixture; (B) adding a first monomer into the first mixture for reaction to obtain a second mixture; and (C) adding a second monomer into the second mixture for reaction to obtain a third mixture; wherein the compound of formula (I) and the catalyst of formula (II) are as defined in the specification.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 26, 2020
    Inventors: Chien-Tien CHEN, Yi-Ya LIAO
  • Patent number: 10224489
    Abstract: A novel compound is disclosed, which comprises: a 7-membered ring segment, which is formed by a cis-stilbene segment and a bridge atom with four bonds; and a fluorene segment connecting to the bridge atom with a double bond. In addition, an organic electronic device is also disclosed, and an organic layer therein comprises the novel compound of the present invention.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: March 5, 2019
    Assignee: NICHEM FINE TECHNOLOGY CO., LTD.
    Inventors: Chien-Tien Chen, Chi-Chung Chen
  • Patent number: 10217947
    Abstract: An organic compound is disclosed. The organic compound includes a cis-stilbene segment, a bridge atom segment having a bridge atom with four bonds, and the bridge atom is connected to the cis-stilbene segment with two of the four bonds to form a 7-membered ring structure, and an imidazole segment connected to the cis-stilbene segment.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: February 26, 2019
    Assignee: NICHEM FINE TECHNOLOGY CO., LTD.
    Inventors: Chien-Tien Chen, Chi-Chung Chen
  • Patent number: 10211410
    Abstract: An organic compound is disclosed. The organic compound includes a cis-stilbene segment, a bridge atom segment having a bridge atom with four bonds, and the bridge atom is connected to the cis-stilbene segment with two of the four bonds to form a 7-membered ring structure, and a quinoxaline segment connected to the cis-stilbene segment.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: February 19, 2019
    Assignee: NICHEM FINE TECHNOLOGY CO., LTD
    Inventors: Chien-Tien Chen, Chi-Chung Chen
  • Patent number: 10193083
    Abstract: The present invention provides a series of spirally configured cis-stilbene/fluorene hybrid compounds and an optoelectronic device comprising the same. The compound comprises a seven-membered ring portion. The seven-membered ring portion is composed of a cis-stilbene fragment, and a tetrahedral coordination bridging atom fragment, wherein the cis-stilbene fragment has at least one substituent, the substituent is independently a substituted or unsubstituted triazine group, pyrimidine group or phenyl group. The compounds have glass transition temperatures ranged from 156° C. to 202° C., decomposition temperatures ranged from 419° C. to 509° C., reversible electron transport property, and balanced charges motilities. In addition, a variety of experimental data have proved that these spirally configured cis-stilbene/fluorene hybrid materials can indeed be used as a hole-blocking type electron-transporter for phosphorescent OLEDs.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: January 29, 2019
    Assignee: NICHEM FINE TECHNOLOGY CO., LTD.
    Inventors: Chien-Tien Chen, Chi-Chung Chen
  • Patent number: 10186667
    Abstract: The present invention provides a series of diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid compounds and an optoelectronic device comprising the same. The diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid compound bearing cyanoaryl and cyanoheteroaryl substituents, and have glass transition temperatures ranged from 154° C. to 194° C., decomposition temperatures ranged from 426° C. to 443° C., reversible electron transport property, and balanced charges motilities. In addition, a variety of experimental data have proved that these diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid materials can indeed be used as a hole-blocking type electron-transporter for phosphorescent OLEDs.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: January 22, 2019
    Assignee: NICHEM FINE TECHNOLOGY CO., LTD.
    Inventors: Chien-Tien Chen, Chi-Chung Chen
  • Publication number: 20180298060
    Abstract: A cyclopeptide is disclosed, which is represented by the following formula (I) or (I?): wherein R1 is defined in the specification. In addition, a pharmaceutical or cosmetic composition comprising the same and a method for preparing the same are also disclosed.
    Type: Application
    Filed: April 17, 2017
    Publication date: October 18, 2018
    Inventor: Chien-Tien CHEN