Patents by Inventor Chiu-Hong But
Chiu-Hong But has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20080070721Abstract: A weight-adjustable golf club head includes a rear lightweight covering and a golf club head body combined therewith. The rear lightweight covering has a rear crown portion and a rear wall portion extended therefrom. The golf club head body is combined with the rear lightweight covering which is designed to have a striking face, a front crown portion and a sole portion. The rear lightweight covering is made from a low specific gravity metal, and is designed to have a thickness less than 0.6 mm. The rear lightweight covering has an inner surface formed with a plurality of reinforcing ribs.Type: ApplicationFiled: September 20, 2006Publication date: March 20, 2008Inventors: Cheng-Jin Chen, Chiu-Hong Tsai
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Patent number: 6870070Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: and a novel process for the preparation of them.Type: GrantFiled: April 29, 2002Date of Patent: March 22, 2005Assignee: Pharmacia & Upjohn CompanyInventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
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Patent number: 6698768Abstract: The sports shoe mainly comprises a pivot, a blocking plate and a latch. The pivot is adapted to pivotally connect the sports shoes to a detachable ice/roller skate and the latch is adapted to securely lock therebetween. The blocking plate is arranged in spaced relationship with the pivot and a space provided therebetween is adapted to receive a pivotal hook seat of the pivot. The latch includes an elastic member and a plurality of guiding studs which are used to increase the sports shoe in assembled reliability for operating the detachable ice/roller skate.Type: GrantFiled: January 4, 2002Date of Patent: March 2, 2004Inventors: Chang Chun-Cheng, Chiu Hong-Young
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Publication number: 20020151596Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: 1Type: ApplicationFiled: April 29, 2002Publication date: October 17, 2002Inventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
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Patent number: 6410787Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: and a novel process for the preparation of them.Type: GrantFiled: February 14, 2001Date of Patent: June 25, 2002Assignee: Pharmacia & Upjohn CompanyInventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
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Publication number: 20010044471Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: 1Type: ApplicationFiled: February 14, 2001Publication date: November 22, 2001Inventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
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Patent number: 6133446Abstract: Novel aromatic bicyclic amines of formula (I) ##STR1## are useful in treating central nervous system disorders and cardiac arrhythmias and cardiac fibrillation.Type: GrantFiled: January 28, 1999Date of Patent: October 17, 2000Assignee: Pharmacia & Upjohn CompanyInventors: Ruth E. TenBrink, Michael D. Ennis, Chiu-Hong Lin, Robert A. Lahti, Arthur G. Romero, John C. Sih
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Patent number: 6084130Abstract: Compounds and their pharmaceutically acceptable salts suitable for treating central nervous system disorders associated with the dopamine D3 receptor activity of structural Formula I: ##STR1##Type: GrantFiled: May 20, 1997Date of Patent: July 4, 2000Assignee: Pharmacia & Upjohn CompanyInventors: Arthur Glenn Romero, William Harold Darlington, Jeffrey A. Leiby, Chiu-Hong Lin, Susanne R. Haadsma-Svensson, Kerry Anne Cleek
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Patent number: 5708018Abstract: Compounds and their pharmaceutically acceptable salts suitable for treating central nervous system disorders associated with the dopamine D3 receptor activity of Formula I: ##STR1## wherein R.sub.1 and R.sub.2 are independently chosen from hydrogen, C.sub.1 -C.sub.8 alkyl, OCH.sub.3, OH, OSO.sub.2 CF.sub.3, OSO.sub.2 CH.sub.3, SOR.sub.5, CO.sub.2 R.sub.5, CONH.sub.2, CONR.sub.5 R.sub.6, COR.sub.5, CN, SO.sub.2 NH.sub.2, SO.sub.2 NR.sub.5 R.sub.6, SO.sub.2 R.sub.5, --OCO--(C.sub.1 -C.sub.6 alkyl), --NCO--(C.sub.1 -C.sub.6 alkyl), --CH.sub.2 O--(C.sub.1 -C.sub.6 alkyl), --CH.sub.2 OH, --CO-Aryl, --NHSO.sub.2 -Aryl, --NHSO.sub.2 --(C.sub.1 -C.sub.6 alkyl), phthalimide, thiophenyl, pyrrol, pyrrolinyl, oxazolyl, or R.sub.1 and R.sub.2 together form --O(CH.sub.2).sub.1-2 O-- or --(CH.sub.2).sub.3-6 -- (except that only one of R.sub.1 and R.sub.2 can be hydrogen or OH in any such compound); R.sub.3 and R.sub.4 are independently chosen from C.sub.2 -C.sub.4 alkenyl, C.sub.3 -C.sub.8 alkynyl, C.sub.3 -C.sub.Type: GrantFiled: February 2, 1996Date of Patent: January 13, 1998Assignee: Pharmacia & Upjohn CompanyInventors: Susanne R. Haadsma-Svensson, Bengt R. Andersson, Clas A. Sonesson, Chiu-Hong Lin, R. Nicholas Waters, Kjell A. I. Svensson, Per A. E. Carlsson, Lars O. Hansson, N. Peter Stjernlof
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Patent number: 5650427Abstract: A compound of Formula I ##STR1## or pharmaceutically acceptable salts of Formula I, where R.sup.1 is H, C.sub.1 -C.sub.3 alkyl, --(CH.sub.2).sub.n CONH.sub.2 where n is 2 to 6, (CH2).sub.n -1-(4,4-dimethylpiperidine-2,6-dione-yl), or cyclopropylmethyl;R.sup.2 is hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 cycloalkyl or combined with R.sup.1 to form a C.sub.3 -C.sub.8 cycloalkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.2 -C.sub.8 akynyl, (CH.sub.2).sub.n --X--Ar where X is O, S, or NH, 3,3,3-trifluoropropyl, --(CH.sub.2).sub.m --R.sup.9 where m is 2 or 3 and R.sup.9 is phenyl, 2-thiophenyl or 3-thiophenyl; R.sup.3 is hydrogen, C.sub.1 -C.sub.3 alkyl, 2,2,2-trifluoroethyl, 3,3,3-trifluoropropyl, formyl, CN, halogen, CH.sub.2 OR.sup.2, C(O)C(O)OR.sup.1, C(O)CO NR.sup.1 R.sup.2, --(CH.sub.2).sub.q --NR.sup.1 R.sup.2 where q is 0 to 5, C.dbd.NOR.sup.2, 2(4,5-dihydro)oxazolyl, or COR.sup.10 where R.sup.10 is H, R.sup.1, NR.sup.1 R.sup.2 or CF.sub.3 ; R.sup.4 is hydrogen, C.sub.1 -C.sub.Type: GrantFiled: June 2, 1995Date of Patent: July 22, 1997Assignee: The Upjohn CompanyInventors: Hakan Vilhelm Wikstrom, Per Arvid Emil Carlsson, Bengt Ronny Andersson, Kjell Anders Ivan Svensson, Stig Thomas Elebring, Nils Peter Stjernlof, Arthur Glenn Romero, Susanne R. Haadsma-Svensson, Chiu-Hong Lin, Michael Dalton Ennis
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Patent number: 5627882Abstract: An enhanced power saving method for operating a battery powered hand-held communication system, particularly a cordless phone system, and the communication system constructed in accordance with the power saving method are described. The power saving method consists of an algorithm which divides the standby time of the communication system into a scanning mode and a sleep mode having several different levels to allow the system to enter the scanning mode intermittently. Each level of the sleep mode corresponds to a given length of delay time between two successive scanning periods. The communication system enters different levels of the sleep mode in accordance with the standby time history. The more standby time that passes, the longer the sleep time for the level that the system may enter. This reduces the scan rate when the system is not used for a long period.Type: GrantFiled: May 26, 1994Date of Patent: May 6, 1997Assignee: U.S. Philips CorporationInventors: Cheng-Tung Chien, Chang-Wen Chen, Chiu-Hong But
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Patent number: 5545755Abstract: This invention is therapeutically useful 2-aminotetralins and pharmaceutically acceptable acid addition salts thereof of the formula ##STR1## R, R.sub.1 to R.sub.5 and p are as defined in the specification, these compounds are useful to treat central nervous system disorders, hypertension, diabetes, sexual impotency and to control appetite.Type: GrantFiled: January 18, 1995Date of Patent: August 13, 1996Assignee: The Upjohn CompanyInventors: Chiu-Hong Lin, Susanne R. Haadsma-Svensson, Montford F. Piercey, Arthur G. Romero, William H. Darlington
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Patent number: 5491236Abstract: This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of the formula ##STR1## wherein R, R.sub.1 and A are as defined in claim 1. These compounds are useful to treat central nervous system disorders.Type: GrantFiled: December 4, 1991Date of Patent: February 13, 1996Assignee: The Upjohn CompanyInventor: Chiu-Hong Lin
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Patent number: 5486611Abstract: This invention is therapeutically useful tetralins and pharmaceutically acceptable acid addition salts thereof of the formula I: ##STR1## wherein X is --(CH.sub.2).sub.n -- or --C(R.sub.1)(H)--; R is C.sub.1 -C.sub.8 alkyl; and R.sub.1 and R.sub.2 are the same or different and are selected from the group consisting of hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.2 -C.sub.8) alkynyl, aryl and benzyl.These compounds are useful to treat central nervous system disorders and are unexpectedly resistant to metabolism by the liver and have superior oral plasma bioavailability.Type: GrantFiled: October 28, 1993Date of Patent: January 23, 1996Assignee: The Upjohn CompanyInventors: Chiu-Hong Lin, Susanne R. Haadsma-Svensson, Robert B. McCall, Arthur G. Romero, William H. Darlington, Michael D. Ennis
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Patent number: 5461061Abstract: A compound of Formula I ##STR1## or pharmaceutically acceptable salts of Formula I, where R.sup.1 is H, C.sub.1 -C.sub.3 alkyl, --(CH.sub.2).sub.n CONH.sub.2 where n is 2 to 6, (CH2).sub.n -1-(4,4-dimethylpiperidine-2,6-dione-yl), or cyclopropylmethyl;R.sup.2 is hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 cycloalkyl or combined with R.sup.1 to form a C.sub.3 -C.sub.8 cycloalkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.2 -C.sub.8 akynyl, (CH.sub.2).sub.n --X--Ar where X is O, S, or NH, 3,3,3-trifluoropropyl, --(CH.sub.2).sub.m --R.sup.9 where m is 2 or 3 and R.sup.9 is phenyl, 2-thiophenyl or 3-thiophenyl; R.sup.3 is hydrogen, C.sub.1 -C.sub.3 alkyl, 2,2,2-trifluoroethyl, 3,3,3-trifluoropropyl, formyl, CN, halogen, CH.sub.2 OR.sup.2, C(O)C(O)OR.sup.1, C(O)CO NR.sup.1 R.sup.2, --(CH.sub.2).sub.q --NR.sup.1 R.sup.2 where q is 0 to 5, C.dbd.NOR.sup.2, 2(4,5-dihydro)oxazolyl, or COR.sup.10 where R.sup.10 is H, R.sup.1, NR.sup.1 R.sup.2 or CF.sub.3 ; R.sup.4 is hydrogen, C.sub.1 -C.sub.Type: GrantFiled: October 28, 1993Date of Patent: October 24, 1995Inventors: Hakan V. Wikstrom, Per A. E. Carlsson, Bengt R. Andersson, Kjell A. I. Svensson, Stig T. Elebring, Nils P. Stjernlof, Arthur G. Romero, Susanne R. Haadsma-Svensson, Chiu-Hong Lin, Michael D. Ennis
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Patent number: 5288748Abstract: A compound of Formula I ##STR1## or pharmaceutically acceptable salts of Formula I, where R.sup.1 is H, C.sub.1 -C.sub.3 alkyl, --(CH.sub.2).sub.n CONH.sub.2 where n is 2 to 6, (CH2).sub.n -1-(4,4-dimethylpiperidine-2,6-dione-yl), or cyclopropylmethyl;R.sup.2 is hydrogen, C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.8 cycloalkyl or combined with R.sup.1 to form a C.sub.3 -C.sub.8 cycloalkyl, C.sub.2 -C.sub.8 alkenyl, C.sub.2 -C.sub.8 akynyl, (CH.sub.2).sub.n --R"--Ar where R" is O, S, or NH, 3,3,3-trifluoropropyl, --(CH.sub.2).sub.m --R.sup.9 where m is 2 or 3 and R.sup.9 is phenyl, 2-thienyl or 3-thienyl; R.sup.3 is hydrogen, C.sub.1 -C.sub.3 alkyl, 2,2,2-trifluoroethyl, 3,3,3-trifluoropropyl, formyl, CN, halogen, CH.sub.2 OR.sup.2, C(O)C(O)OR.sup.1, C(O)CO NR.sup.1 R.sup.2, --(CH.sub.2).sub.q --NR.sup.1 R.sup.2 where q is 0 to 5, C.dbd.NOR.sup.2, 2(4,5-dihydro)oxazolyl, or COR.sup.10 where R.sup.10 is H, R.sup.1, NR.sup.1 R.sup.2 or CF.sub.3 ; R.sup.4 is hydrogen, C.sub.1 -C.sub.3 alkyl, cyclopropylmethyl, CF.Type: GrantFiled: July 1, 1992Date of Patent: February 22, 1994Assignee: The Upjohn CompanyInventors: Hakan V. Wikstrom, Per A. E. Carlsson, Bengt R. Andersson, Kjell A. I. Svensson, Stig T. Elebring, Nils P. Stjernlof, Arthur G. Romero, Susanne R. Haadsma-Svensson, Chiu-Hong Lin, Michael D. Ennis
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Patent number: 5245046Abstract: Provided are novel .alpha.-aminoindole-3-acetic acid derivatives having the formula ##STR1## wherein R through R9 are as defined in the specification, and pharmacologically acceptable salts of compounds wherein R.sub.9 is not OM, which are useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents.Type: GrantFiled: May 8, 1991Date of Patent: September 14, 1993Assignee: The Upjohn CompanyInventors: Gilbert A. Youngdale, John C. Sih, Steven P. Tanis, Chiu-Hong Lin
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Patent number: 4939169Abstract: Novel 1,4-naphthalenediol and 1,4-hydroquinone derivatives of formula I, II, III and IV and their therapeutic uses as 5-lipoxygenase inhibitors, leukotriene inhibitors, antiinflammatory and/or inhibitors of mucus secretion agents are described. Also provided are novel intermediates useful for the preparation of said derivatives.Type: GrantFiled: March 13, 1989Date of Patent: July 3, 1990Assignee: The Upjohn CompanyInventors: Gordon L. Bundy, Chiu-Hong Lin
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Patent number: 4882433Abstract: The present invention provides novel 3'-pyridinylalkenylindole-2-carboxylic acids and derivatives thereof of the formulas I and II ##STR1## which are useful as thromboxane A.sub.2 (TXA.sub.2) synthetase inhibitors and as such represent potent pharmacological agents.Type: GrantFiled: March 28, 1988Date of Patent: November 21, 1989Assignee: The Upjohn CompanyInventors: Roy A. Johnson, Chiu-Hong Lin
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Patent number: 4851586Abstract: Novel 1,4-naphthalenediol and 1,4-hydroquinone derivatives of formulas I, II, III and IV and their therapeutic uses as 5-lipoxygenase inhibitors, leukotriene inhibitors, antiinflammatory and/or inhibitors of mucus secretion agents are described. Also provided are novel intermediates useful for the preparation of said derivatives.Type: GrantFiled: May 18, 1987Date of Patent: July 25, 1989Assignee: The Upjohn CompanyInventors: Gordon L. Bundy, Chiu-Hong Lin