Patents by Inventor Chris Duncan
Chris Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190264153Abstract: The present disclosure is directed to bioreactor consoles that provide a stable structure with built-in bioreactor component management. The bioreactor consoles disclosed herein can include one or more vertical platforms with notches and/or a recessed platform that can provide the desirable flexibility to easily connect and disconnect various tubes, cables, and components of the bioreactor system as well as organize which tubes and cables connect to which component of a bioreactor on the vertical platforms.Type: ApplicationFiled: July 28, 2017Publication date: August 29, 2019Applicant: Juno Therapeutics, Inc.Inventors: Chris Duncan VALBURG, Brian CHRISTIN, Rachel LOWER, Pascal BEAUCHESNE, Dustin John TROIA
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Publication number: 20190211292Abstract: The present disclosure is directed to bioreactor bag assemblies that can minimize the amount of additional connections/adaptations made to the bioreactor bag before the bioreactor bag can be used for cell cultivation, thereby reducing the risk of contamination. The bioreactor bag assemblies disclosed herein can include a pre-assembled waste bag connection and pre-assembled tubing arrangements so that the cell media and/or the cell source can be immediately welded to the pre-assembled tubing arrangements.Type: ApplicationFiled: September 12, 2017Publication date: July 11, 2019Applicant: Juno Therapeutics, Inc.Inventors: Pascal BEAUCHESNE, Chris Duncan VALBURG
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Publication number: 20180016230Abstract: The present invention relates to crystalline 1-adamantanamine salts, and polymorphic forms thereof, of prostaglandin analog intermediates of formula 3a, 4a and 6a, useful in the preparation of Tafluprost and Lubiprostone and processes for their preparation. The process includes combining 1-adamantanamine, water, an organic solvent, and a compound of Formula 3 or 6, thereby obtaining a suspension. The process also includes isolating the solid salt of Formula 3a or 6a from the suspension.Type: ApplicationFiled: December 10, 2015Publication date: January 18, 2018Inventors: Yajun Zhao, Yonggang Li, Uma Kotipalli, Sammy Chris Duncan, Honghai Lv, Kangying Li
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Publication number: 20170291882Abstract: Solid forms of Mirabegron, including forms APO-I, APO-II, and various salt forms, and processes for the preparation thereof, are provided.Type: ApplicationFiled: October 1, 2015Publication date: October 12, 2017Inventors: Allan W. Rey, Annyt Bhattacharyya, Jenny L. Gerster, Sammy Chris Duncan, Mohammed Abdul Raheem, Fan Wang, Stuart P. Green
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Patent number: 9533949Abstract: This invention provides processes for preparation of 3-alkyl indoles of Formula 1: wherein A1, A2 and A3 are independently selected from the group consisting of: H, X, OR1, CN, CONR22 and C02R3; R1 is C1-C6 alkyl; R2 is H or C1-C6 alkyl; R3 is C1-C6 alkyl; LG is a leaving group; X is a halogen; and n is 1, 2 or 3.Type: GrantFiled: September 12, 2013Date of Patent: January 3, 2017Assignee: Apotex Pharmachem Inc.Inventors: Craig Stewart, Peter Garth Blazecka, Gamini Weeratunga, Uma Kotipalli, Sammy Chris Duncan, Yajun Zhao
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Patent number: 9382272Abstract: There is provided processes for preparing Lubiprostone and intermediates thereof. Also provided are compounds, including intermediates for preparing Lubiprostone as well compositions comprising Lubiprostone and other compounds, including intermediates for preparing Lubiprostone and other compounds.Type: GrantFiled: January 22, 2010Date of Patent: July 5, 2016Assignee: Apotex Pharmachem Inc.Inventors: Kiran Kumar Kothakonda, Fan Wang, Bhaskar Reddy Guntoori, Minh T. N. Nguyen, Alfredo Paul Ceccarelli, Yajun Zhao, Uma Kotipalli, Sammy Chris Duncan, Kaarina K. Milnes, Kevin Wade Kells, Laura Kaye Montemayor
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Patent number: 9359374Abstract: Provided for in the instant application are two additional forms of rifaximin, namely rifaximin polymorphic forms APO-III and APO-IV. Also provided are allegedly novel processes for preparing the previously disclosed rifaximin polymorphic forms APO-I and APO-II. Rifaximin is a non-aminoglycoside antibiotic that has previously been found to be useful for the treatment of traveller's diarrhea caused by Escherichia coli bacteria, as well as in the treatment of irritable bowel syndrome, diverticular disease, hepatic encephalopathy, pyogenic skin infections and as an antibacterial prophylactic prior to colon surgery.Type: GrantFiled: June 13, 2013Date of Patent: June 7, 2016Assignee: Apotex Pharmachem Inc.Inventors: Peter Garth Blazecka, Nageib Mohamed, Cameron L. McPhail, Sammy Chris Duncan, Randa E. El-Haj, Yajun Zhao
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Publication number: 20150284407Abstract: Provided for in the instant application are two additional forms of rifaximin, namely rifaximin polymorphic forms APO-III and APO-IV. Also provided are allegedly novel processes for preparing the previously disclosed rifaximin polymorphic forms APO-I and APO-II. Rifaximin is a non-aminoglycoside antibiotic that has previously been found to be useful for the treatment of traveller's diarrhea caused by Escherichia coli bacteria, as well as in the treatment of irritable bowel syndrome, diverticular disease, hepatic encephalopathy, pyogenic skin infections and as an antibacterial prophylactic prior to colon surgery.Type: ApplicationFiled: June 13, 2013Publication date: October 8, 2015Inventors: Peter Garth Blazecka, Nageib Mohamed, Cameron L. McPhail, Sammy Chris Duncan, Randa E. El-Haj, Yajun Zhao
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Publication number: 20150252000Abstract: This invention provides processes for preparation of 3-alkyl indoles of Formula 1: wherein A1, A2 and A3 are independently selected from the group consisting of: H, X, OR1, CN, CONR22 and C02R3; R1 is C1-C6 alkyl; R2 is H or C1-C6 alkyl; R3 is C1-C6 alkyl; LG is a leaving group; X is a halogen; and n is 1, 2 or 3.Type: ApplicationFiled: September 12, 2013Publication date: September 10, 2015Inventors: Craig Stewart, Peter Garth Blazecka, Gamini Weeratunga, Uma Kotipalli, Sammy Chris Duncan, Yajun Zhao
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Publication number: 20120065409Abstract: There is provided processes for preparing Lubiprostone and intermediates thereof. Also provided are compounds, including intermediates for preparing Lubiprostone as well compositions comprising Lubiprostone and other compounds, including intermediates for preparing Lubiprostone and other compounds.Type: ApplicationFiled: January 22, 2010Publication date: March 15, 2012Applicant: APOTEX PHARMACHEM INC.Inventors: Kiran Kumar Kothakonda, Fan Wang, Bhaskar Reddy Guntoori, Minh T. N. Nguyen, Alfredo Paul Ceccarelli, Yajun Zhao, Uma Kotipalli, Sammy Chris Duncan, Kaarina K. Milnes, Kevin Wade Kells, Laura Kaye Montemayor
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Patent number: 7615647Abstract: A process is provided for preparing pharmaceutical grade atorvastatin hemicalcium salt comprising: (a) deesterifying, wherein R is an ester protecting group to (b) extracting R(R*,R*)-3 into an organic solvent or mixture of solvents, (c) adding a base of formula NR1R2R3 wherein R1, R2 and R3 are independently selected from H, substituted or non-substituted C1 to C7 alkyl, C6 to C9 aryl, C8 to C10 aralkyl or aminoalkyl to form atorvastatin base salt, (d) isolating by precipitation of the above atorvastatin base salt and purifying when necessary, (e) converting atorvastatin base salt to atorvastatin hemicalcium salt by treatment with a calcium salt solution, and (f) isolating the atorvastatin hemicalcium salt.Type: GrantFiled: August 5, 2005Date of Patent: November 10, 2009Assignee: Apotex Pharmachem Inc.Inventors: K.S. Keshava Murthy, Yajun Zhao, Daqing Che, Bhaskar Reddy Guntoori, Sammy Chris Duncan, Stephen E. Horne
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Patent number: 7378527Abstract: A process for preparing torsemide or salts thereof comprising: a) reacting II with isopropyl isocyanate in the presence of an alkali carbonate or bicarbonate and an organic solvent to form an alkali torsemide mixture, b) recovering the alkali torsemide mixture, and c) if desired, recovering the torsemide by acidification of the alkali torsemide mixture.Type: GrantFiled: March 16, 2004Date of Patent: May 27, 2008Inventors: Daqing Che, Bhaskar Reddy Guntoori, Sammy Chris Duncan
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Publication number: 20060199855Abstract: A process is provided for preparing pharmaceutical grade atorvastatin hemicalcium salt comprising: (a) deesterifying, wherein R is an ester protecting group to (b) extracting R(R*,R*)-3 into an organic solvent or mixture of solvents, (c) adding a base of formula NR1R2R3 wherein R1, R2 and R3 are independently selected from H, substituted or non-substituted C1 to C7 alkyl, C6 to C9 aryl, C8 to C10 aralkyl or aminoalkyl to form atorvastatin base salt, (d) isolating by precipitation of the above atorvastatin base salt and purifying when necessary,Type: ApplicationFiled: August 5, 2005Publication date: September 7, 2006Inventors: K.S. Keshava Murthy, Yajun Zhao, Daqing Che, Bhaskar Reddy Guntoori, Sammy Chris Duncan, Stephen Horne
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Patent number: 5701499Abstract: The present invention contemplates a method and system for automatically entering a data series into an electronic spreadsheet program or the like. After the user has selected source cells containing the start of the data series, the manipulation may be carried out with little effort on the part of the user. In a preferred embodiment, to enter a data series, the user merely positions the cursor over a predetermined location on the outside border of the source cells, depresses and holds down a predefined mouse button, drags the border to a new location, and then releases the mouse button. The data series is automatically created based on the contents of the source cells and predetermined criteria.Type: GrantFiled: March 25, 1992Date of Patent: December 23, 1997Assignee: Microsoft CorporationInventors: Brian Capson, Wes Cherry, Jon Devaan, Chris Duncan, Raymond E. Fowkes, Christopher E. Graham, Lisa R. James, Timothy W. McGuire, Jr.
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Patent number: 5685001Abstract: A method and system for automatically entering a data series into an electronic spreadsheet program or the like. After the user has selected source cells containing the start of the data series, the manipulation may be carried out with little effort on the part of the user. In a preferred embodiment, to enter a data series, the user merely positions the cursor over a predefined location on the outside border of the source cells, depresses and holds down a predefined mouse button, drags the border to a new location, and then releases the mouse button. The data series is created based on the contents of the source cells and predetermined criteria.Type: GrantFiled: June 7, 1995Date of Patent: November 4, 1997Assignee: Microsoft CorporationInventors: Brian Capson, Wes Cherry, Jon Devaan, Chris Duncan, Raymond E. Fowkes, Christopher E. Graham, Lisa R. James, Timothy W. McGuire, Jr.