Patents by Inventor Chris Lesiak
Chris Lesiak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9809842Abstract: Systems, devices, and methods for accurately imaging chemiluminescence and other luminescence are disclosed. A compact, flat-bed scanner having a light-tight enclosure, one or more detector bars of linear charge-coupled device (CCD) or complementary metal oxide semiconductor (CMOS) imaging chips, and high working numerical aperture (NA) optics scans closely over a sample in one direction and then the opposite direction. Averages or other combinations of intensity readings for each pixel location (x, y) between the two or more passes are averaged together in order to compensate for luminescence that varies over time. On-chip pixel binning and multiple clock frequencies can be used to maximize the signal to noise ratio in a CCD-based scanner.Type: GrantFiled: March 24, 2014Date of Patent: November 7, 2017Assignee: LI-COR, Inc.Inventors: Ahmed Bouzid, Chris Lesiak, Daniel W. Konz, David L. Franzen, William Biggs, Jon P. Anderson
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Patent number: 9366630Abstract: Quantitative fluorescence imaging systems and methods using angular illumination to obtain automatic focus information. Laser scanning (e.g., point or line scanning) with angular illumination in combination with an area imaging sensor, such as with a bi-telcentric scanner, is used to determine sample height (relative to a detection axis orthogonal to a platform holding the sample) and also correct for sample height in subsequent scans.Type: GrantFiled: September 8, 2014Date of Patent: June 14, 2016Assignee: LI-COR, Inc.Inventors: Ahmed Bouzid, Chris Lesiak
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Publication number: 20160069808Abstract: Quantitative fluorescence imaging systems and methods using angular illumination to obtain automatic focus information. Laser scanning (e.g., point or line scanning) with angular illumination in combination with an area imaging sensor, such as with a bi-telcentric scanner, is used to determine sample height (relative to a detection axis orthogonal to a platform holding the sample) and also correct for sample height in subsequent scans.Type: ApplicationFiled: September 8, 2014Publication date: March 10, 2016Inventors: Ahmed BOUZID, Chris LESIAK
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Publication number: 20140206568Abstract: Systems, devices, and methods for accurately imaging chemiluminescence and other luminescence are disclosed. A compact, flat-bed scanner having a light-tight enclosure, one or more detector bars of linear charge-coupled device (CCD) or complementary metal oxide semiconductor (CMOS) imaging chips, and high working numerical aperture (NA) optics scans closely over a sample in one direction and then the opposite direction. Averages or other combinations of intensity readings for each pixel location (x, y) between the two or more passes are averaged together in order to compensate for luminescence that varies over time. On-chip pixel binning and multiple clock frequencies can be used to maximize the signal to noise ratio in a CCD-based scanner.Type: ApplicationFiled: March 24, 2014Publication date: July 24, 2014Applicant: LI-COR, Inc.Inventors: Ahmed Bouzid, Chris Lesiak, Daniel W. Konz, David L. Franzen, William Biggs, Jon P. Anderson
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Patent number: 8722346Abstract: Systems, devices, and methods for accurately imaging chemiluminescence and other luminescence are disclosed. A compact, flat-bed scanner having a light-tight enclosure, one or more detector bars of linear charge-coupled device (CCD) or complementary metal oxide semiconductor (CMOS) imaging chips, and high working numerical aperture (NA) optics scans closely over a sample in one direction and then the opposite direction. Averages or other combinations of intensity readings for each pixel location (x, y) between the two or more passes are averaged together in order to compensate for luminescence that varies over time. On-chip pixel binning and multiple clock frequencies can be used to maximize the signal to noise ratio in a CCD-based scanner.Type: GrantFiled: June 17, 2013Date of Patent: May 13, 2014Assignee: Li-Cor, Inc.Inventors: Ahmed Bouzid, Chris Lesiak, Daniel W. Konz, David L. Franzen, William Biggs, Jon P. Anderson
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Publication number: 20130280737Abstract: Systems, devices, and methods for accurately imaging chemiluminescence and other luminescence are disclosed. A compact, flat-bed scanner having a light-tight enclosure, one or more detector bars of linear charge-coupled device (CCD) or complementary metal oxide semiconductor (CMOS) imaging chips, and high working numerical aperture (NA) optics scans closely over a sample in one direction and then the opposite direction. Averages or other combinations of intensity readings for each pixel location (x, y) between the two or more passes are averaged together in order to compensate for luminescence that varies over time. On-chip pixel binning and multiple clock frequencies can be used to maximize the signal to noise ratio in a CCD-based scanner.Type: ApplicationFiled: June 17, 2013Publication date: October 24, 2013Applicant: Li-Cor, Inc.Inventors: Ahmed Bouzid, Chris Lesiak, Daniel W. Konz, David L. Franzen, William Biggs, Jon P. Anderson
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Patent number: 8486644Abstract: Systems, devices, and methods for accurately imaging chemiluminescence and other luminescence are disclosed. A compact, flat-bed scanner having a light-tight enclosure, one or more detector bars of linear charge-coupled device (CCD) or complementary metal oxide semiconductor (CMOS) imaging chips, and high working numerical aperture (NA) optics scans closely over a sample in one direction and then the opposite direction. Averages or other combinations of intensity readings for each pixel location (x, y) between the two or more passes are averaged together in order to compensate for luminescence that varies over time. On-chip pixel binning and multiple clock frequencies can be used to maximize the signal to noise ratio in a CCD-based scanner.Type: GrantFiled: March 28, 2012Date of Patent: July 16, 2013Assignee: Li-Cor, Inc.Inventors: Ahmed Bouzid, Chris Lesiak, Daniel W. Konz, David L. Franzen, William Biggs, Jon P. Anderson
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Publication number: 20130157282Abstract: Systems, devices, and methods for accurately imaging chemiluminescence and other luminescence are disclosed. A compact, flat-bed scanner having a light-tight enclosure, one or more detector bars of linear charge-coupled device (CCD) or complementary metal oxide semiconductor (CMOS) imaging chips, and high working numerical aperture (NA) optics scans closely over a sample in one direction and then the opposite direction. Averages or other combinations of intensity readings for each pixel location (x, y) between the two or more passes are averaged together in order to compensate for luminescence that varies over time. On-chip pixel binning and multiple clock frequencies can be used to maximize the signal to noise ratio in a CCD-based scanner.Type: ApplicationFiled: March 28, 2012Publication date: June 20, 2013Applicant: Li-Cor, Inc.Inventors: Ahmed Bouzid, Chris Lesiak, Daniel W. Konz, David L. Franzen, William Biggs, Jon P. Anderson