Patents by Inventor CHRISTA BUECKER

CHRISTA BUECKER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR HOMOLOGOUS RECOMBINATION IN HUMAN CELLS
    Publication number: 20140193913
    Abstract: The methods and compositions described herein are based, in part, on the discovery of a stem cell state in human cells that resembles the morphology observed in murine-derived stem cells. Induction of such a state in human stem cells permits an increase in the efficiency of homologous recombination. Thus, the methods and compositions described herein relate to cells and methods for increasing the efficiency of homologous recombination in human stem cells.
    Type: Application
    Filed: August 16, 2013
    Publication date: July 10, 2014
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Niels Geijsen, Christa Buecker
  • Methods and compositions for homologous recombination in human cells
    Patent number: 8524498
    Abstract: The methods and compositions described herein are based, in part, on the discovery of a stem cell state in human cells that resembles the morphology observed in murine-derived stem cells. Induction of such a state in human stem cells permits an increase in the efficiency of homologous recombination. Thus, the methods and compositions described herein relate to cells and methods for increasing the efficiency of homologous recombination in human stem cells.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: September 3, 2013
    Assignee: The General Hospital Corporation
    Inventors: Niels Geijsen, Christa Buecker
  • METHODS AND COMPOSITIONS FOR HOMOLOGOUS RECOMBINATION IN HUMAN CELLS
    Publication number: 20100304489
    Abstract: The methods and compositions described herein are based, in part, on the discovery of a stem cell state in human cells that resembles the morphology observed in murine-derived stem cells. Induction of such a state in human stem cells permits an increase in the efficiency of homologous recombination. Thus, the methods and compositions described herein relate to cells and methods for increasing the efficiency of homologous recombination in human stem cells.
    Type: Application
    Filed: June 1, 2010
    Publication date: December 2, 2010
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: NIELS GEIJSEN, CHRISTA BUECKER