Patents by Inventor Christiaan Hubert Simon Roelant
Christiaan Hubert Simon Roelant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190041304Abstract: A method and apparatus for the manipulation for an identification purpose of a microcarrier. The method comprising the steps of: (a) an identification purpose step of the microcarrier; and (b) a positioning and orientation step prior to or during the identification purpose step. The apparatus comprising means for identification purposes such as a microscope or labelling means such as a high spatial resolution light source, and means for the positioning and orientation of the microcarriers.Type: ApplicationFiled: October 10, 2018Publication date: February 7, 2019Applicant: MYCARTIS NVInventors: Marc Jan Rene LEBLANS, Emmanuel Marie Paul Ernest GUSTIN, Christiaan Hubert Simon ROELANT, Stefaan Cornelis DE SMEDT, Joseph DEMEESTER, Kevin BRAECKMANS
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Patent number: 8967483Abstract: Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the encoded microcarriers. A preferred method of encoding the microcarriers involves exposing microcarriers containing a bleachable substance to a high spatial resolution light source to bleach the codes on the microcarriers. The encoded microcarriers may be used, for example, as support materials in chemical and biological assays and syntheses.Type: GrantFiled: March 25, 2014Date of Patent: March 3, 2015Assignee: MyCartis NVInventors: Stefaan Cornelis De Smedt, Joseph Demeester, Christiaan Hubert Simon Roelant, Rudi Wilfried Jan Pauwels
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Publication number: 20150057190Abstract: Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the encoded microcarriers. A preferred method of encoding the microcarriers involves exposing microcarriers containing a bleachable substance to a high spatial resolution light source to bleach the codes on the microcarriers. The encoded microcarriers may be used, for example, as support materials in chemical and biological assays and syntheses.Type: ApplicationFiled: October 31, 2014Publication date: February 26, 2015Applicant: MyCartis NVInventors: Stefaan Cornelis De Smedt, Joseph Demeester, Christiaan Hubert Simon Roelant, Rudi Wilfried Jan Pauwels
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Patent number: 8939376Abstract: Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the encoded microcarriers. A preferred method of encoding the microcarriers involves exposing microcarriers containing a bleachable substance to a high spatial resolution light source to bleach the codes on the microcarriers. The encoded microcarriers may be used, for example, as support materials in chemical and biological assays and syntheses.Type: GrantFiled: April 12, 2000Date of Patent: January 27, 2015Assignee: Mycartis NVInventors: Stefaan Cornelis De Smedt, Joseph Demeester, Christiaan Hubert Simon Roelant, Rudi Wilfried Jan Pauwels
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Publication number: 20140249050Abstract: Disclosed is a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and (b) a positioning and orientation step prior to or during the identification purpose step. Also disclosed is an apparatus for the manipulation for identification purposes of a microcarrier comprising means for identification purposes such as a microscope or labelling means such as a high spatial resolution light source, and means for the positioning and orientation of the microcarriers.Type: ApplicationFiled: May 16, 2014Publication date: September 4, 2014Applicant: BIOCARTIS SAInventors: Marc Jan René LEBLANS, Emmanuel Marie Paul Ernest GUSTIN, Christiaan Hubert Simon ROELANT, Stefaan Cornelis DE SMEDT, Joseph DEMEESTER, Kevin BRAECKMANS
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Publication number: 20140206569Abstract: Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the encoded microcarriers. A preferred method of encoding the microcarriers involves exposing microcarriers containing a bleachable substance to a high spatial resolution light source to bleach the codes on the microcarriers. The encoded microcarriers may be used, for example, as support materials in chemical and biological assays and syntheses.Type: ApplicationFiled: March 25, 2014Publication date: July 24, 2014Applicant: Biocartis SAInventors: Stefaan Cornelis De Smedt, Joseph Demeester, Christiaan Hubert Simon Roelant, Rudi Wilfried Jan Pauwels
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Patent number: 8735172Abstract: The present invention relates to a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and (b) a positioning and orientation step prior to or during the identification purpose step, wherein the identification purpose step is a detection step for the detection of an encoded microcarrier having an anisotropy in its shape. The invention further relates to an apparatus for the manipulation for identification purposes of a microcarrier comprising means for identification purposes such as a microscope and means for the positioning and orientation of the microcarriers.Type: GrantFiled: September 22, 2010Date of Patent: May 27, 2014Assignee: Biocartis S.A.Inventors: Marc Jan René Leblans, Emmanuel Marie Paul Ernest Gustin, Christiaan Hubert Simon Roelant, Joseph Demeester, Stefaan Cornelis De Smedt, Kevin Braeckmans
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Publication number: 20110082046Abstract: The present invention relates to a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and (b) a positioning and orientation step prior to or during the identification purpose step, wherein the identification purpose step is a detection step for the detection of an encoded microcarrier having an anisotropy in its shape. The invention further relates to an apparatus for the manipulation for identification purposes of a microcarrier comprising means for identification purposes such as a microscoper and means for the positioning and orientation of the microcarriers.Type: ApplicationFiled: September 22, 2010Publication date: April 7, 2011Applicant: Universiteit GentInventors: Marc Jan René LEBLANS, Emmanuel Marie Paul Ernest Gustin, Christiaan Hubert Simon Roelant, Stefaan Cornelis De Smedt, Joseph Demeester, Kevin Braeckmans
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Patent number: 7045312Abstract: The present invention is directed to reporter molecules and tags that may be used to monitor a target substance in a biological system. More particularly, the present invention relates to the use of an apo metal binding protein as a reporter molecule or tag. An apo metal binding protein may be bound to a protein or tissue or introduced into a cell. The invention also relates to methods of utilizing the apo metal binding protein for detecting a cell expressing a protein of interest, localizing a protein in a cell, and designing a therapeutic agent for treating a disease or infection.Type: GrantFiled: September 8, 2004Date of Patent: May 16, 2006Inventors: Inge Dierynck, Christiaan Hubert Simon Roelant, Rudi Wilfried Jan Pauwels, Koenraad Lodewijk August Van Acker, Jan Octaaf Antoon De Kerpel
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Patent number: 6868875Abstract: A method for dispensing a volume of fluids from a reservoir, through a fluid outlet in fluid communication with said reservoir, into each well of at least a series of wells, whereby the fluid is dispensed into said series of wells at a continuous uninterrupted flow. A micro titer plate constructed from a hydrophobic and more in particular from a plastic material containing a plurality of series of wells and to an apparatus able to perform the above method.Type: GrantFiled: March 8, 2001Date of Patent: March 22, 2005Assignee: Tibotec BVBAInventors: Werner René Irène De Beukeleer, Christiaan Hubert Simon Roelant
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Patent number: 6800437Abstract: The present invention is directed to reporter molecules and tags that may be used to monitor a target substance in a biological system. More particularly, the present invention relates to the use of an apo metal binding protein as a reporter molecule or tag. An apo metal binding protein may be bound to a protein or tissue or introduced into a cell. The invention also relates to methods of utilizing the apo metal binding protein for detecting a cell expressing a protein of interest, localizing a protein in a cell, and designing a therapeutic agent for treating a disease or infection.Type: GrantFiled: August 4, 2000Date of Patent: October 5, 2004Assignee: Tibotec BvbaInventors: Inge Dierynck, Christiaan Hubert Simon Roelant, Rudi Wilfried Jan Pauwels, Koenraad Lodewijk August Van Acker, Jan Octaaf Antoon De Kerpel
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Publication number: 20030155034Abstract: The present invention relates to a method for dispensing a volume of fluids from a reservoir, through a fluid outlet in fluid communication with said reservoir, into each well of at least a series of wells, whereby the method comprises a dispensing mode and a non-dispensing mode, whereby the fluid is dispensed into said series of wells at a continuous uninterrupted flow.Type: ApplicationFiled: February 5, 2003Publication date: August 21, 2003Inventors: Werner Rene Irene De Beukeleer, Christiaan Hubert Simon Roelant
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Publication number: 20020081629Abstract: A method for the rapid screening of analytes, such as potential drug candidates, comprises the steps of applying a plurality of analytes to be screened onto one or more, solid support(s) (61) such that the analytes remain isolated from one another; contacting said analyte-carrying solid support(s) (61) with targets provided in a semi-solid or liquid medium, whereby said analytes are released from the solid support(s) (61) to the targets; and measuring analyte-target interactions. This method allows for the manipulation of thousands of different analytes simultaneously. When the analyte is applied to the solid support (61) it can diffuse thereon so as to produce a concentration gradient and serial dilution of analyte if a dose response curve for a candidate drug is required. The method described can be readily automated.Type: ApplicationFiled: December 19, 2001Publication date: June 27, 2002Applicant: TIBOTEC N.V.Inventors: Rudi Wilfried Jan Pauwels, Christiaan Hubert Simon Roelant, Koenraad Lodewijk August Van Acker