Patents by Inventor Christian A. Clausen
Christian A. Clausen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090214614Abstract: The present invention provides for a method for tissue engineering by cell implantation that involves the use of a scaffold in situ at the site of a defect, where the therapeutic cells are fixed in place into the scaffold only once the scaffold is inserted at the site of the tissue defect, thereby locking not only the cells to the scaffold, but also the scaffold to the tissue defect. The invention also provides a kit of parts suitable for performing the method of the invention.Type: ApplicationFiled: September 5, 2006Publication date: August 27, 2009Applicant: INTERFACE BIOTECH A/SInventors: Hanne Everland, Christian Clausen, Kurt Osther
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Patent number: 7518905Abstract: This invention provides novel high density memory devices that are electrically addressable permitting effective reading and writing, that provide a high memory density (e.g., 1015 bits/cm3), that provide a high degree of fault tolerance, and that are amenable to efficient chemical synthesis and chip fabrication. The devices are intrinsically latchable, defect tolerant, and support destructive or non-destructive read cycles. In a preferred embodiment, the device comprises a fixed electrode electrically coupled to a storage medium having a multiplicity of different and distinguishable oxidation states wherein data is stored in said oxidation states by the addition or withdrawal of one or more electrons from said storage medium via the electrically coupled electrode.Type: GrantFiled: November 2, 2005Date of Patent: April 14, 2009Assignees: The Regents of the University of California, North Carolina State UniversityInventors: David F Bocian, Werner G Kuhr, Jonathan Lindsey, Peter Christian Clausen, Daniel Tomasz Gryko
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Publication number: 20080253999Abstract: The present invention relates to a method for propagating and/or differentiating mammalian cells, the method comprising exposing or co-culturing mammalian cells with one or more of periodontal ligament tissue, periodontal ligament proteins or factors derived from periodontal ligament tissue, to obtain cells having PDL characteristics and fulfilling at least one of the following: i) show periodontal characteristics as evidenced with Von Kossa method in which calcium phosphate deposits are stained brown to black, ii) show increased osteopontin and osteocalcin and at the same time decreased bone sialoprotein (bone sialoprotein II or BSP), iii) are capable of being implanted to repair and/or regenerate periodontal tissue, iv) are capable of repairing disorders such as paradentitis also called paradentosis, or periodontitis by healing of the gum line towards the teeth, and v) are accepted by the host without significant immune reaction or cell rejection.Type: ApplicationFiled: September 28, 2006Publication date: October 16, 2008Inventors: Kurt Osther, Christian Clausen, Klaus Riskaer Pedersen
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Publication number: 20080177125Abstract: Emulsified systems of a surfactant-stabilized, biodegradable water-in-solvent emulsion with bimetallic particles contained with the emulsion droplets are useful at removing PCBs from ex situ structures. The hydrophobic emulsion system draws PCBs through the solvent/surfactant membrane. Once inside the membrane, the PCBs diffuse into the bimetallic particles and undergo degradation. The PCBs continue to enter, diffuse, degrade, and biphenyl will exit the particle maintaining a concentration gradient across the membrane and maintaining a driving force of the reaction.Type: ApplicationFiled: August 15, 2007Publication date: July 24, 2008Applicant: U.S.A as Represented by the Administrator of the National Aeronautics and Space AdInventors: Jacqueline Quinn, Christian Clausen, Cherie L. Geiger, Christina Coon, Laura B. Filipek, Cristina M. Berger, Kristen M. Milum
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Publication number: 20070287628Abstract: A hydrogenation catalyst including a base material coated with a catalytic metal is made using mechanical milling techniques. The hydrogenation catalysts are used as an excellent catalyst for the dehalogenation of contaminated compounds and the remediation of other industrial compounds. Preferably, the hydrogenation catalyst is a bimetallic particle including zero-valent metal particles coated with a catalytic material. The mechanical milling technique is simpler and cheaper than previously used methods for producing hydrogenation catalysts.Type: ApplicationFiled: May 17, 2007Publication date: December 13, 2007Applicant: USA as Represented by the Administrator of the National Aeronautics and Space AdmInventors: Jacqueline W. Quinn, Christian A. Clausen, Cherie L. Geiger, Brian S. Aitken
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Patent number: 7271199Abstract: Emulsified systems of a surfactant-stabilized, biodegradable water-in-solvent emulsion with bimetallic particles contained with the emulsion droplets are useful at removing PCBs from ex situ structures. The hydrophobic emulsion system draws PCBs through the solvent/surfactant membrane. Once inside the membrane, the PCBs diffuse into the bimetallic particles and undergo degradation. The PCBs continue to enter, diffuse, degrade, and biphenyl will exit the particle maintaining a concentration gradient across the membrane and maintaining a driving force of the reaction.Type: GrantFiled: October 27, 2004Date of Patent: September 18, 2007Assignee: United States of America as Represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Jacqueline Quinn, Christian Clausen, Cherie L. Geiger, Christina Coon, Cristina M. Berger, Laura B. Filipek, Kristen M. Milum
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Publication number: 20070112243Abstract: PCBs are removed from contaminated media using a treatment system including catalyzed zero-valent metal particles and an organic hydrogen donating solvent. This treatment system provides a major benefit of eliminating PCBs in situ. The treatment system provides a “paste”-like system that is preferably applied to natural media and ex-situ structures.Type: ApplicationFiled: August 7, 2006Publication date: May 17, 2007Applicant: United States of America as Represented by the Administrator of the National Aeronautics and SpacInventors: Jacqueline Quinn, Kathleen Brooks, Cherie Geiger, Christian Clausen
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Patent number: 7042755Abstract: This invention provides novel high density memory devices (FIG. 3) that are electrically addressable permitting effective reading and writing, that provide a high memory density (102), that provide a high degree of fault tolerance, and that are amenable to efficient chemical synthesis and chip fabrication. The devices arc intrinsically latchable, defect tolerant, and support destructive or non-destructive read cycles. In a preferred embodiment, the device comprises a fixed electrode electrically coupled to a storage medium having a multiplicity of different and distinguishable oxidation states wherein data is stored in said oxidation states by the addition or withdrawal of one or more electrons from said storage medium via the electrically coupled electrode.Type: GrantFiled: June 28, 2000Date of Patent: May 9, 2006Inventors: David F. Bocian, Werner G. Kuhr, Jonathan Lindsey, Peter Christian Clausen, Daniel Tomasz Gryko
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Patent number: 7037946Abstract: A zero-valent metal emulsion is used to dehalogenate solvents, such as pooled dense non-aqueous phase liquids (DNAPLs), including trichloroethylene (TCE). The zero-valent metal emulsion contains zero-valent metal particles, a surfactant, oil and water. The preferred zero-valent metal particles are nanoscale and microscale zero-valent iron particles.Type: GrantFiled: October 31, 2003Date of Patent: May 2, 2006Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Debra R. Reinhart, Christian Clausen, Cherie L. Geiger, Jacqueline Quinn, Kathleen Brooks
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Patent number: 7008964Abstract: A zero-valent metal emulsion containing zero-valent metal particles is used to remediate contaminated natural resources, such as groundwater and soil. In a preferred embodiment, the zero-valent metal emulsion removes heavy metals, such as lead (Pb), from contaminated natural resources. In another preferred embodiment, the zero-valent metal emulsion is a bimetallic emulsion containing zero-valent metal particles doped with a catalytic metal to remediate halogenated aromatic compounds, such as polychlorinated biphenyls (PCBs), from natural resources.Type: GrantFiled: May 28, 2003Date of Patent: March 7, 2006Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Christian A. Clausen, Jacqueline W. Quinn, Cheri L. Geiger, Debra Reinhart, Laura B. Filipek, Christina Coon, Robert Devor
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Publication number: 20050013890Abstract: A solid imaging apparatus and method produces an integral three-dimensional object from a multiplicity of cross sectional portions of the object by selectively exposing successive layers of a liquid photoformable composition to actinic radiation. The apparatus includes a vessel for containing the composition so as to present a free surface, and a movable platform disposed within the vessel below the free surface. Part of the composition is transferred above the free surface by lowering and raising a dispenser at predetermined positions located away from the platform. A doctor blade contacts the composition transferred above the free surface, and then moves over the platform to form a substantially uniform layer of the composition.Type: ApplicationFiled: January 16, 2004Publication date: January 20, 2005Inventors: Brian Chapman, Christian Clausen, Daniel Mickish, Eustathios Vassiliou
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Publication number: 20040069720Abstract: A zero-valent metal emulsion containing zero-valent metal particles is used to remediate contaminated natural resources, such as groundwater and soil. In a preferred embodiment, the zero-valent metal emulsion removes heavy metals, such as lead (Pb), from contaminated natural resources. In another preferred embodiment, the zero-valent metal emulsion is a bimetallic emulsion containing zero-valent metal particles doped with a catalytic metal to remediate halogenated aromatic compounds, such as polychlorinated biphenyls (PCBs), from natural resources.Type: ApplicationFiled: May 28, 2003Publication date: April 15, 2004Inventors: Christian A. Clausen, Jacqueline W. Quinn, Cherie L. Geiger, Debra Reinhart, Laura B. Filipek, Christina Coon, Robert Devor
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Patent number: 6676912Abstract: A method for removing NOX from gas streams emanating from stationary combustion sources and manufacturing plants utilizes the injection of hydrogen peroxide into the gas stream for rapid gas-phase oxidation of NO to NO2 and water-soluble nitrogen acids HNO2 and HNO3. The nitrogen acids may be removed from the oxidized gas stream by wet scrubbing or by contact with a particulate alkaline material to form a nitrite/nitrate salt.Type: GrantFiled: October 27, 2000Date of Patent: January 13, 2004Assignee: The United States of America as represented by the Administrator of the National Aeronautics & Space AdministrationInventors: Charles D. Cooper, Christian A. Clausen, III, Michelle M. Collins
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Patent number: 6664298Abstract: A zero-valent metal emulsion is used to dehalogenate solvents, such as pooled dense non-aqueous phase liquids (DNAPLs), including trichloroethylene (TCE). The zero-valent metal emulsion contains zero-valent metal particles, a surfactant, oil and water.Type: GrantFiled: October 2, 2001Date of Patent: December 16, 2003Assignee: The United States of America as represented by the Administrator of the National Aeronautics & Space AdministrationInventors: Debra R. Reinhart, Christian Clausen, Cherie L. Geiger, Jacqueline Quinn, Kathleen Brooks
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Patent number: 6324091Abstract: This invention provides novel high density memory devices that are electrically addressable permitting effective reading and writing, that provide a high memory density (e.g., 1015 bits/cm3), that provide a high degree of fault tolerance, and that are amenable to efficient chemical synthesis and chip fabrication. The devices are intrinsically latchable, defect tolerant, and support destructive or non-destructive read cycles. In a preferred embodiment, the device comprises a fixed electrode electrically coupled to a storage medium comprising a storage molecule comprising a first subunit and a second subunit wherein the first and second subunits are tightly coupled such that oxidation of the first subunit alters the oxidation potential(s) of the second subunit rendering the oxidation potential(s) of the second unit different and distinguishable from the oxidation potentials of the first subunit.Type: GrantFiled: January 14, 2000Date of Patent: November 27, 2001Assignee: The Regents of the University of CaliforniaInventors: Daniel Tomasz Gryko, Peter Christian Clausen, David F. Bocian, Werner G. Kuhr, Jonathan S. Lindsey
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Patent number: 6208553Abstract: This invention provides novel high density memory devices that are electrically addressable permitting effective reading and writing, that provide a high memory density (e.g., 1015 bits/cm3), that provide a high degree of fault tolerance, and that are amenable to efficient chemical synthesis and chip fabrication. The devices are intrinsically latchable, defect tolerant, and support destructive or non-destructive read cycles. In a preferred embodiment, the device comprises a fixed electrode electrically coupled to a storage medium comprising one or more thiol-derivatized porphyrins. The storage medium has a multiplicity of different and distinguishable oxidation states and data is stored in said oxidation states by the addition or withdrawal of one or more electrons from the storage medium via the electrically coupled electrode(s).Type: GrantFiled: July 1, 1999Date of Patent: March 27, 2001Assignee: The Regents of the University of CaliforniaInventors: Daniel Tomasz Gryko, Peter Christian Clausen, Kristian M. Roth, David F. Bocian, Werner G. Kuhr, Jonathan S. Lindsey
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Patent number: 6013232Abstract: A method for increasing the effectiveness of a permeable treatment wall is described. The method includes the introduction of ultrasonic radiation in or near the wall. A permeable treatment wall is also described which has an ultrasonic radiation generating transducer in or near the wall. Permeable treatment walls are described as having either a well vertically extending into the wall, or a rod vertically extending into the treatment wall. Additionally, a method for adapting a permeable treatment wall to allow for the introduction of ultrasonic radiation in or near the wall is described.Type: GrantFiled: July 31, 1997Date of Patent: January 11, 2000Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Jacqueline W. Quinn, Christian A. Clausen, Cherie L. Geiger, Debra R. Reinhart, Nancy Ruiz
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Patent number: 4040652Abstract: A door lock having a press button operable to retract the door bolt from its engaged to its released position, and a separate operating means to positively lock the bolt whereby the press button is raised or lowered from its normal position so as to serve as a visual signal indicating whether the bolt is locked or is free for normal retraction.Type: GrantFiled: February 11, 1974Date of Patent: August 9, 1977Assignee: Daempa A/SInventors: Soren Christian Schoubye Arfelt, Ib Christian Clausen, Johannes Jensen, Knud Hansen Fynbo, Jean Arnold Fischer