Patents by Inventor Christian Gehring
Christian Gehring has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240092186Abstract: The invention relates to a method for operating an electric drive system of a motor vehicle (2) with a backup battery (2.8) and a fuel cell (2.6) for providing electric drive power. Here, route data is determined and then, based on this route data, consumption data is forecast. The invention is characterized in that, in order to optimize the operation of the fuel cell (2.6) based on the forecast consumption data, a total energy demand for the route is forecast, after which a mean fuel cell power is determined which is required together with the energy stored at the starting time of the route in the backup battery (2.8) to determine the total energy demand over a constant power trajectory for the fuel cell (2.6). This is followed by a check as to whether limit values of the backup battery (2.8) are violated when driving along the route with the power trajectory: if no limit value is violated, the fuel cell (2.Type: ApplicationFiled: July 5, 2021Publication date: March 21, 2024Inventors: Ottmar GEHRING, Christian BALLARIN, Steffen MAUS
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Patent number: 11421254Abstract: A method for oxidizing an alkyl, including a) contacting the alkyl with an aqueous solution comprising a microorganism where the microorganism has a reduced fatty acid degradation capacity compared to its wild type, wherein the fatty acid degradation capacity is reduced by deletion, inhibition or inactivation of a gene encoding an enzyme involved in the ?-oxidation pathway; and the microorganism expresses a recombinant alkane oxidase, and b) contacting the aqueous solution from a) with a water-immiscible organic solvent.Type: GrantFiled: October 7, 2020Date of Patent: August 23, 2022Assignee: Evonik Operations GmbHInventors: Thomas Haas, Oliver Thum, Jan Christoph Pfeffer, Philip Engel, Christian Gehring, Markus Poetter
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Publication number: 20210024967Abstract: A method for oxidizing an alkyl, including a) contacting the alkyl with an aqueous solution comprising a microorganism where the microorganism has a reduced fatty acid degradation capacity compared to its wild type, wherein the fatty acid degradation capacity is reduced by deletion, inhibition or inactivation of a gene encoding an enzyme involved in the ?-oxidation pathway; and the microorganism expresses a recombinant alkane oxidase, and b) contacting the aqueous solution from a) with a water-immiscible organic solvent.Type: ApplicationFiled: October 7, 2020Publication date: January 28, 2021Applicant: Evonik Operations GmbHInventors: Thomas HAAS, Oliver Thum, Jan Christoph Pfeffer, Philip Engel, Christian Gehring, Markus Poetter
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Publication number: 20200063172Abstract: The present invention relates to a microbial cell for producing at least one L-amino acid from at least one C1-C4 alkane, wherein the cell comprises: (i) an increased expression relative to the wild type cell of Enzyme E1 capable of converting the alkane to a corresponding 1-alkanol; (ii) an increased expression relative to the wild type cell of Enzyme E2 capable of converting the 1-alkanol of (i) to a corresponding aldehyde; and either (iii) (A) an increased expression relative to the wild type cell of Enzyme E3 capable of converting the aldehyde of (ii) to a corresponding alkanoic acid; and a wild-type level expression of Enzyme E4 or an increased expression relative to the wild type cell of Enzyme E4 capable of converting the alkanoic acid of (iii) to a corresponding fatty acyl thioester; or ?(B) an increased expression relative to the wild type cell of Enzyme E5 capable of converting the aldehyde of (ii) to a corresponding fatty acyl thioester; ?and (iv) an increased expression relative to the wiType: ApplicationFiled: August 21, 2019Publication date: February 27, 2020Applicant: Evonik Degussa GmbHInventors: Philip Engel, Steffen Schaffer, Oliver Thum, Heiko Andrea, Christian Gehring, Bastian Grund
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Patent number: 10450590Abstract: The invention relates to a process for preparing an ?,?-alkanediol comprising the steps of a) reacting an alkanoic acid with an alkanol to give an ester, b) oxidizing at least one terminal carbon atom of the ester by contacting with a whole-cell catalyst, which expresses an alkane hydroxylase, in aqueous solution and in the presence of molecular oxygen, to give an oxidized ester, c) hydrogenating the oxidized ester to form the alkanediol and alkanol, and d) removing the alkanol by distillation, forming a reaction mixture depleted with respect to the alkanol, and recycling the alkanol in step b).Type: GrantFiled: January 10, 2014Date of Patent: October 22, 2019Assignee: Evonik Degussa GmbHInventors: Thomas Haas, Philip Engel, Jan Christoph Pfeffer, Oliver Thum, Christian Gehring
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Patent number: 10174353Abstract: The present invention relates to a method of preparing at least one rhamnolipid comprising: contacting a recombinant cell with a medium containing a carbon source; and culturing the cell under suitable conditions for preparation of the rhamnolipid from the carbon source by the cell, wherein the recombinant cell has been genetically modified such that, compared to the wild-type of the cell, the cell has an increased activity of at least one of the enzymes E1, E2 and E3, wherein the enzyme E1 is an ?/? hydrolase, the enzyme E2 is a rhamnosyltransferase I and the enzyme E3 is a rhamnosyl-transferase II, and wherein the carbon source is a C4 molecule.Type: GrantFiled: April 27, 2015Date of Patent: January 8, 2019Assignee: Evonik Degussa GmbHInventors: Oliver Thum, Philip Engel, Christian Gehring, Steffen Schaffer, Mirja Wessel
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Patent number: 10053713Abstract: The invention relates to a method for oxidizing an alkane, comprising contacting the alkane with a type alkB oxidoreductase and using a type alkB oxidoreductase to prepare a mixture of oxidation products of an alkane, wherein the ratio of carboxylic acid to alcohol in the oxidation products is preferably greater than 1:1.Type: GrantFiled: November 22, 2012Date of Patent: August 21, 2018Assignee: EVONIK DEGUSSA GmbHInventors: Jan Christoph Pfeffer, Thomas Haas, Oliver Thum, Frank Erhardt, Eva Maria Wittmann, Christian Gehring, Sabine Hafkemeyer, Thomas Hueller
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Publication number: 20170096695Abstract: The present invention relates to a method of preparing at least one rhamnolipid comprising: contacting a recombinant cell with a medium containing a carbon source; and culturing the cell under suitable conditions for preparation of the rhamnolipid from the carbon source by the cell, wherein the recombinant cell has been genetically modified such that, compared to the wild-type of the cell, the cell has an increased activity of at least one of the enzymes E1, E2 and E3, wherein the enzyme E1 is an ?/? hydrolase, the enzyme E2 is a rhamnosyltransferase I and the enzyme E3 is a rhamnosyl-transferase II, and wherein the carbon source is a C4 molecule.Type: ApplicationFiled: April 27, 2015Publication date: April 6, 2017Inventors: OLIVER THUM, PHILIP ENGEL, CHRISTIAN GEHRING, STEFFEN SCHAFFER, MIRJA WESSEL
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Publication number: 20150353963Abstract: The invention relates to a process for preparing an ?,?-alkanediol comprising the steps of a) reacting an alkanoic acid with an alkanol to give an ester, b) oxidizing at least one terminal carbon atom of the ester by contacting with a whole-cell catalyst, which expresses an alkane hydroxylase, in aqueous solution and in the presence of molecular oxygen, to give an oxidized ester, c) hydrogenating the oxidized ester to form the alkanediol and alkanol, and d) removing the alkanol by distillation, forming a reaction mixture depleted with respect to the alkanol, and recycling the alkanol in step b).Type: ApplicationFiled: January 10, 2014Publication date: December 10, 2015Inventors: Thomas HAAS, Philip ENGEL, Jan Christoph PFEFFER, Oliver THUM, Christian GEHRING
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Publication number: 20150299741Abstract: The present invention relates to a method comprising the steps a) providing an alkane or 1-alkanol, b) contacting said alkane or 1-alkanol in an aqueous solution with a cytochrome P450 alkane hydroxylase from the CYP153 family and oxygen for at least 3 hours.Type: ApplicationFiled: November 6, 2013Publication date: October 22, 2015Applicant: EVONIK INDUSTRIES AGInventors: Philip ENGEL, Thomas HAAS, Jan Christoph PFEFFER, Oliver THUM, Christian GEHRING
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Publication number: 20150275245Abstract: The present invention relates to a microorganism having a reduced fatty acid degradation capacity and expressing a recombinant alkane oxidase, a method for oxidizing an alkyl, comprising a contacting the alkyl with an aqueous solution comprising the inventive cell.Type: ApplicationFiled: December 14, 2012Publication date: October 1, 2015Applicant: EVONIK INDUSTRIES AGInventors: Thomas Haas, Oliver Thum, Jan Christoph Pfeffer, Philip Engel, Christian Gehring, Markus Poetter
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Publication number: 20150218600Abstract: The invention relates to a method comprising the steps a) providing isobutyric acid, b) bringing isobutyric acid into contact with the combination of isobutyrate kinase and phosphotransisobutyrylase and/or isobutyryl-coenzyme A synthetase/ligase and/or isobutyrate-coenzyme A transferase, c) bringing the product from step a) into contact with isobutyryl-coenzyme A dehydrogenase, d) bringing the product from step b) into contact with methacrylyl-coenzyme A hydratase, and e) hydrolyzing the product from step d) to form 3-hydroxyisobutyric acid, where at least one of the enzymes is used in the form of a cell which, compared to its wildtype, comprises a reduced activity of a 3-hydroxyisobutyric acid dehydrogenase or a variant thereof, a cell which has at least one enzyme from the group comprising isobutyryl-coenzyme A synthetase/ligase, isobutyrate-coenzyme A transferase, isobutyrate kinase, phosphotransisobutyrylase, isobutyryl-coenzyme A dehydrogenase, methacrylyl-coenzyme A hydratase and 3-hydroxyisobutyryl-coeType: ApplicationFiled: November 14, 2012Publication date: August 6, 2015Applicant: Evonik Degussa GmbHInventors: Thomas Haas, Steffen Schaffer, Markus Poetter, Mirja Wessel, Jan Christoph Pfeffer, Christian Gehring, Nicole Kirchner, Eva Maria Wittmann
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Publication number: 20150044744Abstract: The invention relates to a method for oxidizing an alkane, comprising contacting the alkane with a type alkB oxidoreductase and using a type alkB oxidoreductase to prepare a mixture of oxidation products of an alkane, wherein the ratio of carboxylic acid to alcohol in the oxidation products is preferably greater than 1:1.Type: ApplicationFiled: November 22, 2012Publication date: February 12, 2015Applicant: EVONIK INDUSTRIES AGInventors: Jan Christoph Pfeffer, Thomas Haas, Oliver Thum, Frank Erhardt, Eva Maria Wittmann, Christian Gehring, Sabine Hafkemeyer, Thomas Hueller
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Publication number: 20150010968Abstract: The present invention relates to method for oxidising an alkene comprising contacting said alkene with an AlkB-type oxidoreductase in the presence of oxygen, and a use of an AlkB-type oxidoreductase, preferably AlkB from Pseudomonas putida GPO1 or a variant thereof, for oxidising an alkene to an alcohol and/or acid.Type: ApplicationFiled: January 18, 2013Publication date: January 8, 2015Applicant: Evonik Industries AGInventors: Philip Engel, Thomas Haas, Jan Christoph Pfeffer, Oliver Thum, Christian Gehring