Abstract: The present invention relates to compounds of formula I a process for their manufacture, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment and/or prevention of conditions having an association with the function of metabotropic glutamate receptor subtype 4 (mGluR4). A, R1, R2, R3, R4, R5 and R6 have meanings given in the description.

Abstract: The present invention relates to substituted dioxane derivatives, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment and/or prevention of neuronal and non-neuronal conditions having an association with mGluR4 function and/or in the treatment of obesity by means of mGluR4 modulation.

Abstract: The low-inertia and high-strength accelerating lever comprises a hub part, arm and end part made of a thermoplastics reinforced by high-strength fibers. The lever is built up from a number of layers in the form a Prepregs or semifinisheds, which are placed one on another, the layers having different fiber orientations and extending substantially parallel to the movement plane. Longitudinal components of the fiber orientations predominate in the arm with a gradual transition to the hub part and end part; the hub part and end part having a substantially isotropic distribution of the fiber orientations.

Abstract: An apparatus for transferring parisons used for blow moulding and consisting of plastic from a conveying path to a receiving wheel. For this purpose, a transfer wheel is provided which receives the parisons in compartments, turns them through 180.degree. and transfers them in modified orientation to a receiving wheel.