Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention relates to tricyclic compounds comprising a diazepinone moiety which are effective in inhibiting Sppl2a (signal peptide peptidase like protease 2a), to pharmaceutical compositions containing such inhibitors, and to methods of using such inhibitors and compositions.

Abstract: The invention relates to a tire pressure sensor that includes a pressure transducer, a transmitter, and a housing carrying the pressure transducer and the transmitter, adapted to be mounted to an air inlet end of a tire valve; wherein the housing has a sleeve part which has an internal thread at the end for screwing the sleeve part onto the tire valve. The tire pressure sensor according to the invention is characterized in that the housing further has a receiving part in or on which the pressure sensor and the transmitter are arranged and which, in the mounted state, is connected to the sleeve part so as to be rotatable relative to the sleeve part.

Abstract: The present invention describes novel heteroaryl butanoic acid derivatives that are good drug candidates especially with regard to leukotriene A4 hydrolase (LTA4H). The present invention also relates to pharmaceutical compositions comprising said novel heteroaryl butanoic acid derivatives, methods of using said compounds in the treatment of various diseases and disorders, and processes for preparing the said novel compounds.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention describes novel heteroaryl butanoic acid derivatives that are good drug candidates especially with regard to leukotriene A4 hydrolase (LTA4H). The present invention also relates to pharmaceutical compositions comprising said novel heteroaryl butanoic acid derivatives, methods of using said compounds in the treatment of various diseases and disorders, and processes for preparing the said novel compounds.

Abstract: The invention relates to a fastening apparatus for fastening a measuring sensor, such as a tire pressure sensor, within a tire cavity on a vehicle rim, having a band-shaped tensioning belt which has a receiving device for the measuring sensor; wherein the band-shaped tensioning belt comprises an elastic material. The fastening apparatus according to the invention is characterized in that the band-shaped tensioning belt is provided in the form of a continuous endless belt, which is closed on its circumference and is only elastic in sections.

Abstract: The present invention describes novel heteroaryl butanoic acid derivatives that are good drug candidates especially with regard to leukotriene A4 hydrolase (LTA4H). The present invention also relates to pharmaceutical compositions comprising said novel heteroaryl butanoic acid derivatives, methods of using said compounds in the treatment of various diseases and disorders, and processes for preparing the said novel compounds.

Abstract: A hydraulic actuator includes a cylinder, a pump, an electric motor and a central block. The mechanism or the rotating parts of the pump are directly installed in an interior of the block, and the drive shaft of the pump is correspondingly mounted in walls or in covers of the block.

Abstract: The invention relates to a tire pressure sensor comprising a pressure transducer, a transmitter, and a housing carrying the pressure transducer and the transmitter, adapted to be mounted to an air inlet end of a tire valve; wherein the housing has a sleeve part which has an internal thread at the end for screwing the sleeve part onto the tire valve. The tire pressure sensor according to the invention is characterized in that the housing further comprises a receiving part in or on which the pressure sensor and the transmitter are arranged and which, in the mounted state, is connected to the sleeve part so as to be rotatable relative to the sleeve part.

Abstract: The invention relates to a fastening apparatus for fastening a measuring sensor such as a tire pressure sensor within a tire cavity on a vehicle rim, in particular a utility vehicle rim, comprising a band-shaped tensioning belt which carries a receiving device for the measuring sensor. The fastening apparatus according to the invention is characterized in that the tensioning belt is produced from a material shrinking with the supply of heat, such that the tensioning belt shortens its length under heat supply.

Abstract: The invention relates to an antenna for a receiver or transmitter in a motor vehicle, comprising an electrically conductive loop, which surrounds an area for the passage of electromagnetic waves, which interact with an electric current flow through the loop. The loop has a connection side, via which an electric current can be introduced into the loop or drawn from the loop inductively or by means at least one electrical connection. The antenna according to the invention is characterized in that the area surrounded by the loop is twisted over a twist axis that is perpendicular to or at an angle to the connection side.

Abstract: The invention relates to a tire pressure sensing device for detecting the tire pressure in a pneumatic tire, comprising a pressure sensor (6) in a housing (1); a tire valve (11) or another retainer to be fastened to the rim, which bears the housing; a spring element (2), which is connected to the tire valve or the other retainer at one end and to the housing (1) at the other end, wherein the spring element is partially embedded in the housing and the housing has at least one opening (4, 5) in the area in which the spring element is embedded, said opening being partially or completely opened up by a soft component (13), which partially surrounds the spring element.

Abstract: A hydraulic actuator includes a cylinder, a pump, an electric motor and a central block. The mechanism or the rotating parts of the pump are directly installed in an interior of the block, and the drive shaft of the pump is correspondingly mounted in walls or in covers of the block.

Abstract: The invention concerns a fixing device for fixing a measuring sensor, such as a tire pressure sensor inside a tire cavity on a vehicle rim, in particular utility vehicle rim, comprising a band-shaped tension belt, which carries a receiving device for the measuring sensor: The invention is characterized in that the tension belt contains at a first end an eyelet for threading a second end opposite the first end, and starting from the second end and away from the first end on the surface of the tension belt, two textile fields are positioned behind one another in the longitudinal direction of the tension belt, one of which is fitted with barbed hooks and the other with loops to form together a Velcro fastener after folding the textile fields together on top of each other.

Abstract: The invention relates to a tire-monitoring system for monitoring a tire air pressure and/or at least one other tire-specific quantity in tires of a vehicle; —comprising a plurality of tire sensors for positioning in the tires of the vehicle; —each tire sensor having at least one sensing device for sensing a tire-specific quantity and a control device that has at least one transmitter for transmitting signals in dependence on the sensed quantity and/or a quantity previously programmed in the control device; —and comprising a router for installing in the vehicle, which router comprises a receiver for receiving the signals of the plurality of tires sensors, a memory for storing the quantities of the tire sensors transmitted by means of the signals, and an interface for the wired or wireless retrieval of the stored quantities; —the router having an electrical power connection, by means of which the router can be connected to a vehicle electrical system for the supply of power to the router.

Abstract: The present invention describes novel heteroaryl butanoic acid derivatives that are good drug candidates especially with regard to leukotriene A4 hydrolase (LTA4H). The present invention also relates to pharmaceutical compositions comprising said novel heteroaryl butanoic acid derivatives, methods of using said compounds in the treatment of various diseases and disorders, and processes for preparing the said novel compounds.

Abstract: The present invention describes novel heteroaryl butanoic acid derivatives that are good drug candidates especially with regard to leukotriene A4 hydrolase (LTA4H). The present invention also relates to pharmaceutical compositions comprising said novel heteroaryl butanoic acid derivatives, methods of using said compounds in the treatment of various diseases and disorders, and processes for preparing the said novel compounds.

Abstract: The invention relates to a fastening apparatus for fastening a measuring sensor such as a tire pressure sensor within a tire cavity on a vehicle rim, in particular a utility vehicle rim, comprising a band-shaped tensioning belt which carries a receiving device for the measuring sensor. The fastening apparatus according to the invention is characterized in that the tensioning belt is produced from a material shrinking with the supply of heat, such that the tensioning belt shortens its length under heat supply.

Abstract: The invention relates to a fastening apparatus for fastening a measuring sensor, such as a tire pressure sensor, within a tire cavity on a vehicle rim, having a band-shaped tensioning belt which has a receiving device for the measuring sensor; wherein the band-shaped tensioning belt comprises an elastic material. The fastening apparatus according to the invention is characterized in that the band-shaped tensioning belt is provided in the form of a continuous endless belt, which is closed on its circumference and is only elastic in sections.