Abstract: The present disclosure provides a duplex or single-stranded siRNA molecule against plasminogen, the siRNA molecule containing modified or unmodified nucleotides and wherein at least one strand of the duplex or the single-stranded siRNA has a sequence that has at least 80% sequence identity to any one of SEQ NOs: 1 to 28. Further provided is a duplex or single-stranded siRNA molecule against plasminogen, the siRNA molecule containing modified or unmodified nucleotides and is between 25 and 35 nucleotides in length. The siRNA molecule may be formulated in a lipid nanoparticle as described herein.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device identifies a subset of contacts selected at least in part by a user of the telecommunications device. The subset of contacts includes a portion of the user's contacts accessible by the telecommunications device. The software application causes display of a first portion of graphical identifiers associated with a first portion of the subset of contacts along a first path on a display of the telecommunications device about an axis positioned external to the display of the telecommunications device. The software application further causes display of a second portion of graphical identifiers associated with a second portion of the subset of contacts along a second path on the display of the telecommunications device about the external axis.

Abstract: Group-based information displays correspond to the collection of display objects representative of either contacts associated with a user or applications or executable components executable, or otherwise accessible, via the mobile communication device. The group-based information displays can be logically organized according to subject matter organizational criteria. The subject matter organizational criteria can include, for example, organization or other affiliates criteria, event-based, or activity based criteria, topic-based criteria and the like. Through the group-based information displays, mobile communication device users can initiate one or more actions corresponding to the selection of display objects corresponding to applications or executable components. Additionally, as applicable, the user can limit, or otherwise apply, the initiated actions to contacts identified, or otherwise associated, with the specific group-based information display.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of user contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device determines at least two contact groups from a subset of contacts accessible by a telecommunications device. The software application executed by the processor of the telecommunications device also generates a contact display including a representation of at least a portion of the first or second contact groups and a divider display object. The divider display object partitions the first contact group from the second contact group and is positioned adjacent to at least one contact from the first or second contact groups presented in the contact display.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of user contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device determines at least two contact groups from a subset of contacts accessible by a telecommunications device. The software application executed by the processor of the telecommunications device also generates a contact display including a representation of at least a portion of the first or second contact groups and a divider display object. The divider display object partitions the first contact group from the second contact group and is positioned adjacent to at least one contact from the first or second contact groups presented in the contact display.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of user contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device determines at least two contact groups from a subset of contacts accessible by a telecommunications device. The software application executed by the processor of the telecommunications device also generates a contact display including a representation of at least a portion of the first or second contact groups and a divider display object. The divider display object partitions the first contact group from the second contact group and is positioned adjacent to at least one contact from the first or second contact groups presented in the contact display.

Abstract: Group-based information displays correspond to the collection of display objects representative of either contacts associated with a user or applications or executable components executable, or otherwise accessible, via the mobile communication device. The group-based information displays can be logically organized according to subject matter organizational criteria. The subject matter organizational criteria can include, for example, organization or other affiliates criteria, event-based, or activity based criteria, topic-based criteria and the like. Through the group-based information displays, mobile communication device users can initiate one or more actions corresponding to the selection of display objects corresponding to applications or executable components. Additionally, as applicable, the user can limit, or otherwise apply, the initiated actions to contacts identified, or otherwise associated, with the specific group-based information display.

Abstract: An automated interface generates a tree of design actions based on a predetermined design specification, each intermediary node of the tree representing a partial user interface design, and each branch of the tree representing a design action that creates or modifies the partial user interface design. A plurality of candidate user interface designs are determined, each implementing the received plurality of functions, by traversing the tree along multiple traversal paths from a root node of the tree to respective leaf nodes of the tree and executing respective design actions represented by branches along the traversal paths. A completed interface design is selected from the plurality of completed interface designs, and the final user interface is generated based on the selected candidate user interface design.

Abstract: Group-based information displays correspond to the collection of display objects representative of either contacts associated with a user or applications or executable components executable, or otherwise accessible, via the mobile communication device. The group-based information displays can be logically organized according to subject matter organizational criteria. The subject matter organizational criteria can include, for example, organization or other affiliates criteria, event-based, or activity based criteria, topic-based criteria and the like. Through the group-based information displays, mobile communication device users can initiate one or more actions corresponding to the selection of display objects corresponding to applications or executable components. Additionally, as applicable, the user can limit, or otherwise apply, the initiated actions to contacts identified, or otherwise associated, with the specific group-based information display.

Abstract: An automated interface generates a tree of design actions based on a predetermined design specification, each intermediary node of the tree representing a partial user interface design, and each branch of the tree representing a design action that creates or modifies the partial user interface design. A plurality of candidate user interface designs are determined, each implementing the received plurality of functions, by traversing the tree along multiple traversal paths from a root node of the tree to respective leaf nodes of the tree and executing respective design actions represented by branches along the traversal paths. A completed interface design is selected from the plurality of completed interface designs, and the final user interface is generated based on the selected candidate user interface design.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device identifies a subset of contacts selected at least in part by a user of the telecommunications device. The subset of contacts includes a portion of the user's contacts accessible by the telecommunications device. The software application causes display of a first portion of graphical identifiers associated with a first portion of the subset of contacts along a first path on a display of the telecommunications device about an axis positioned external to the display of the telecommunications device. The software application further causes display of a second portion of graphical identifiers associated with a second portion of the subset of contacts along a second path on the display of the telecommunications device about the external axis.

Abstract: A broom attachment is provided for a rotary sweeper assembly that includes a broom mount and a broom unit mountable to the broom mount. The broom attachment includes a plurality of broom attachment bristles and a support member having a retained portion and a retaining portion. The plurality of bristles extend from the retaining portion and the retained portion is operatively mountable to at least one of the broom mount and the broom unit. A broom assembly includes at least one broom attachment. When the broom attachment is operatively mounted to the broom mount, the broom attachment bristles are positioned at a greater radial distance away from an axis of rotation than the cleaning bristles of the broom unit. A method of assembling a broom attachment to a broom mount includes operatively mounting the retained portion to the broom mount.

Abstract: Systems, methods, and computer-readable mediums for managing contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device identifies a first subset of contacts selected at least in part by a user of the telecommunications device and a second subset of contacts. Each of the first and second subsets includes a portion of the user's contacts accessible by the telecommunications device. The software application causes display of a graphical identifier associated with each contact of the first subset of contacts in a first arrangement on a display of the telecommunications device about a first axis positioned external to the display. The software application further causes display of a graphical identifier associated with each contact of the second subset of contacts in a second arrangement on a display of the telecommunications device about a second axis positioned external to the display.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of user contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device identifies a subset of contacts selected at least in part by a user of the telecommunications device. The subset of contacts includes a portion of the user's contacts accessible by the telecommunications device. The software application executed by the processor of the telecommunications device then causes display of a graphical identifier associated with each contact of the subset of contacts in an arrangement on a display of the telecommunications device about an axis positioned external to the display of the telecommunications device. Aspects of systems, methods, and computer-readable mediums for further arranging the graphical identifiers are also provided.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device identifies a subset of contacts selected at least in part by a user of the telecommunications device. The subset of contacts includes a portion of the user's contacts accessible by the telecommunications device. The software application causes display of a first portion of graphical identifiers associated with a first portion of the subset of contacts along a first path on a display of the telecommunications device about an axis positioned external to the display of the telecommunications device. The software application further causes display of a second portion of graphical identifiers associated with a second portion of the subset of contacts along a second path on the display of the telecommunications device about the external axis.

Abstract: An automated interface generates a tree of design actions based on a predetermined set of functions and relationship information, each intermediary node of the tree representing a partial user interface design, and each branch of the tree representing a design action that creates or modifies the partial user interface design. A plurality of candidate user interface designs are determined, each implementing the received plurality of functions, by traversing the tree along multiple traversal paths from a root node of the tree to respective leaf nodes of the tree and executing respective design actions represented by branches along the traversal paths. A completed interface design is selected from the plurality of completed interface designs based on a predetermined selection algorithm, and the final user interface is generated based on the selected candidate user interface design.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of user contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device determines at least two contact groups from a subset of contacts accessible by a telecommunications device. The software application executed by the processor of the telecommunications device also generates a contact display including a representation of at least a portion of the first or second contact groups and a divider display object. The divider display object partitions the first contact group from the second contact group and is positioned adjacent to at least one contact from the first or second contact groups presented in the contact display.

Abstract: An automated interface generates a tree of design actions based on a predetermined set of functions and relationship information, each intermediary node of the tree representing a partial user interface design, and each branch of the tree representing a design action that creates or modifies the partial user interface design. A plurality of candidate user interface designs are determined, each implementing the received plurality of functions, by traversing the tree along multiple traversal paths from a root node of the tree to respective leaf nodes of the tree and executing respective design actions represented by branches along the traversal paths. A completed interface design is selected from the plurality of completed interface designs based on a predetermined selection algorithm, and the final user interface is generated based on the selected candidate user interface design.

Abstract: Systems, methods, and computer-readable mediums for managing a subset of user contacts on a telecommunications device are provided. In one embodiment, a software application executed by a processor of a telecommunications device determines at least two contact groups from a subset of contacts accessible by a telecommunications device. The software application executed by the processor of the telecommunications device also generates a contact display including a representation of at least a portion of the first or second contact groups and a divider display object. The divider display object partitions the first contact group from the second contact group and is positioned adjacent to at least one contact from the first or second contact groups presented in the contact display.