Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: A wire-binding device for binding together at least two objects comprises a handle part via which the wire-binding device can be held by an operator. Pushing forward the handle part causes a V-shaped wire clip to be guided along the inside of two closing jaws of a mouth until the wire clip encloses the two objects which are to be connected. Additionally provided on the mouth is positioned having two mutually opposite guide faces of which the spacing from one another is less than the spacing of the closing jaws from one another.

Abstract: A wire-binding device for binding together at least two objects comprises a handle part via which the wire-binding device can be held by an operator. Pushing forward the handle part causes a V-shaped wire clip to be guided along the inside of two closing jaws of a mouth until the wire clip encloses the two objects which are to be connected. Additionally provided on the mouth is positioned having two mutually opposite guide faces of which the spacing from one another is less than the spacing of the closing jaws from one another.

Abstract: In a mixer in which several video signal inputs are multiplied by respective mixing factor signals and the multiplier outputs are added together to produce an output video signal, one of the video inputs is given priority and the mixing factors for the other video inputs are premultiplied by a second set of multipliers in such a manner that the video input of next priority will not have an amplitude greater than what is "left over" by the higher priority signal, and so on in descending order of priority. For further flexibility it is useful to provide a third set of multipliers to allow more external control inputs to participate in determining mixing factors and facilitate special effects. A multiplier of the third set is not necessary for control of the mixing factor of the video input of lowest priority. Even a multiplier of the second set is not strictly necessary for that lowest priority video input.

Abstract: Before the camera is used to transmit a scene, a key or button (21) is actuated which causes a measurement field generator (23) to define a small portion of the picture field, where the video signal level of the greatest of the three color components will be compared with a reference level in an aperture control circuit (6) for setting the camera lens aperture. If this should result in a lens aperture above an upper limit or below a lower limit, an amplification step control (26) for an amplifier (8) is shifted one step so as to bring the lens aperture between the aforesaid limits. The comparison of the video signal level with the reference level is repeated until the amplification is sufficient to bring the lens aperture into the desired range. The measurement field is shown in the camera finder (14) and likewise any off-limits setting of the lens aperture and whether the manual control (28) is on a setting that permits the automatic amplification control to operate.