Abstract: An aircraft includes wings having integrated ducted fans. The integrated ducted fans each have a duct with a stiffness ring. Each stiffness ring is made up of stiffness boxes and circular-arc-shaped ring segments. The stiffness boxes can include first stiffness boxes and second stiffness boxes, and the first stiffness boxes and second stiffness boxes differ in terms of height.

Abstract: The invention relates to a compound comprising a GLP-1 receptor agonist and an amylin receptor agonist. The invention also relates to a pharmaceutical formulation, suitable for but not limited to oral administration, which comprises such a compound. The compound and pharmaceutical formulation comprising it may be used for the medical treatment of subjects with overweight, obesity and associated co-morbidities.

Abstract: The invention relates to a method for producing a ceramic moulded body, comprising the following steps: a) producing a green body containing ceramic material, binding agents and an organic pore forming agent; b) heating the green body to a temperature equal to or higher than the sublimation temperature of the pore forming agent; c) burning the green body to form a ceramic moulded body. According to the invention that the organic pore forming agent is selected from the group consisting of dicarboxylic acids and mixtures of dicarboxylic acids, the sublimation temperature being at least 80 k lower than the decomposition temperature.

Abstract: A ducted fan of an aircraft includes a rotor-side fan and a stator-side duct that surrounds the rotor-side fan radially at the outside and that defines a flow channel for air flowing via the fan. The stator-side duct has an inner wall facing toward the fan, an outer wall averted from the fan, and at least one stiffening strut that runs within the flow channel. The stiffening strut, at one respective end, extends through the duct and protrudes radially relative to the outer wall of the duct. At the respective end of the stiffening strut, a fastening device is formed. The fastening device is configured to mount the ducted fan on a structural component of the aircraft. The fastening device has an insert composed of a fiber-reinforced plastic and laminated into the respective end of the stiffening strut.

Abstract: The invention relates to a method for producing a ceramic moulded body, comprising the following steps: a) producing a green body containing ceramic material, binding agents and an organic pore forming agent; b) heating the green body to a temperature higher than the sublimation and/or decomposition temperature of the pore forming agent; c) burning the green body to form a ceramic moulded body. According to the invention, the binding agent comprises polyglycols and fumaric acid.

Abstract: A ducted fan for an aircraft includes a rotor-side fan and a stator-side duct that surrounds the rotor-side fan. The stator-side duct includes an inner wall facing the rotor-side fan and an outer wall averted from the fan. The ducted fan further includes a fastening device configured to support mounting of the ducted fan on a structural component of the aircraft. The fastening device includes a pin and a guide body. The guide body is configured to receive and guide the pin, the pin is insertable proceeding from the inner wall into a recess of the guide body, a first end of the pin protrudes relative to the outer wall, and the pin is configured to be mounted, via the first end, on a bearing of the structural component of the aircraft.

Abstract: A ducted fan for an aircraft includes a rotor-side fan and a stator-side duct that surrounds the rotor-side fan. The stator-side duct includes an inner wall facing the rotor-side fan and an outer wall averted from the fan. The ducted fan further includes a fastening device configured to support mounting of the ducted fan on a structural component of the aircraft. The fastening device includes a pin and a guide body. The guide body is configured to receive and guide the pin, the pin is insertable proceeding from the inner wall into a recess of the guide body, a first end of the pin protrudes relative to the outer wall, and the pin is configured to be mounted, via the first end, on a bearing of the structural component of the aircraft.

Abstract: A ducted fan of an aircraft includes a rotor-side fan and a stator-side duct that surrounds the rotor-side fan radially at the outside and that defines a flow channel for air flowing via the fan. The stator-side duct has an inner wall facing toward the fan, an outer wall averted from the fan, and at least one stiffening strut that runs within the flow channel. The stiffening strut, at one respective end, extends through the duct and protrudes radially relative to the outer wall of the duct. At the respective end of the stiffening strut, a fastening device is formed. The fastening device is configured to mount the ducted fan on a structural component of the aircraft. The fastening device has an insert composed of a fiber-reinforced plastic and laminated into the respective end of the stiffening strut.

Abstract: A ducted fan for an aircraft includes a rotor-side fan and a stator-side duct that surrounds the rotor-side fan. The stator-side duct includes an inner wall facing the rotor-side fan and an outer wall averted from the fan. The inner wall and outer wall each includes at least one layer composed of fiber-reinforced plastic. At least two honeycomb cores are arranged between the inner wall and the outer wall, the at least two honeycomb cores abutting against one another in an axial direction of the ducted fan. The honeycombs of the at least two honeycomb cores extend at least substantially in a radial direction of the ducted fan. A first of the at least two honeycomb cores is, at least in a region of an abutting surface that adjoins another of the at least two honeycomb cores, enwound or encased by at least one layer composed of fiber-reinforced plastic.

Abstract: An aircraft includes wings having integrated ducted fans. The integrated ducted fans each have a duct with a stiffness ring. Each stiffness ring is made up of stiffness boxes and circular-arc-shaped ring segments. The stiffness boxes can include first stiffness boxes and second stiffness boxes, and the first stiffness boxes and second stiffness boxes differ in terms of height.

Abstract: An aircraft includes wings with integrated ducted fans. The ducted fans each have a duct, and each respective duct is made up of inlet regions and outlet regions. Different ducts of different ducted fans can have different construction variants, but the outlet regions of respective ducts can be of identical or mirror-symmetrical shape with respect to one another in all construction variants.

Abstract: An aircraft includes wings with integrated ducted fans. The ducted fans each have a duct with cutouts and a guide grille fitted into the cutouts. The guide grilles can be adhesively bonded into the cutouts. The ducted fans can have different construction variants of the duct, wherein the cutouts have a corresponding shape across all construction variants.

Abstract: The application discloses compounds useful in treatment of diabetes, weight loss and/or reduction of cardiovascular risks. The compounds are bi-functional and therefore suitable as a simple treatment for patients that may benefit from treatment with both a GLP-1 receptor agonist and a PCSK9 inhibitor.

Abstract: The present invention relates to novel peptide compounds which are effective as melanocortin 4 receptor agonists, to the use of the compounds in medicine, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds for the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of overweight and obesity as well as a variety of diseases or conditions associated with obesity.

Abstract: The application discloses compounds useful in treatment of diabetes, weight loss and/or reduction of cardiovascular risks. The compounds are bi-functional and therefore suitable as a simple treatment for patients that may benefit from treatment with both a GLP-1 receptor agonist and a PCSK9 inhibitor.

Abstract: The present invention relates to novel peptide compounds which are effective as melanocortin 4 receptor agonists, to the use of the compounds in medicine, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds for the manufacture of 5 medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity or overweight as well as a variety of diseases or conditions associated with obesity.

Abstract: A software module calculates a 3D tool path with integrated reference variable generation for interpolating moving single axes of a precision machine. A precision machine has a control or drive servo-side interface, in order to read in advance for machining calculated files with equitemporal reference variables for interpolating single axes of the precision machine and to stream to the position and/or velocity controller of the respective individual axes. A method calculates a 3D tool path and a component is produced with this precision machine or with such a method.

Abstract: In a method for calculating reference variables for interpolating moving single axes of a precision machine based on a given 3D tool path firstly for all points of the tool path offline assuming a freely selected path velocity or single-axis velocity, the velocity, acceleration and jerk profiles of all the interpolating axes are calculated cohesively and without specifying limiting values and then velocity, acceleration or jerk profiles are varied on regions on the 3D tool path.

Abstract: The invention relates to a method for producing a ceramic moulded body, comprising the following steps: a) producing a green body containing ceramic material, binding agents and an organic pore forming agent; b) heating the green body to a temperature higher than the sublimation and/or decomposition temperature of the pore forming agent; c) burning the green body to form a ceramic moulded body. According to the invention, the binding agent comprises polyglycols and fumaric acid.

Abstract: The invention relates to a method for producing a ceramic moulded body, comprising the following steps: a) producing a green body containing ceramic material, binding agents and an organic pore forming agent; b) heating the green body to a temperature equal to or higher than the sublimation temperature of the pore forming agent; c) burning the green body to form a ceramic moulded body. According to the invention that the organic pore forming agent is selected from the group consisting of dicarboxylic acids and mixtures of dicarboxylic acids, the sublimation temperature being at least 80 k lower than the decomposition temperature.