Abstract: Methods of safely inducing a protective immune response against respiratory syncytial virus (RSV) and methods of preventing infection and/or replication of RSV in human subjects are described. The methods include administering to the subjects (a) an effective amount of an adenoviral vector encoding a recombinant RSV F protein that is stabilized in a pre-fusion conformation, and (b) an effective amount of an RSV F protein that is stabilized in a pre-fusion conformation.

Abstract: Methods of inducing an immune response against human immunodeficiency virus (HIV) are described. In particular, methods of inducing an immune response against HIV by co-locally administering an immunogenically effective amount of an isolated HIV envelope (Env) polypeptide and an immunogenically effective amount of an adenovirus vector encoding an HIV antigen, e.g., Env antigen are described. The isolated HIV Env polypeptide and adenovirus vector can be administered in a single composition or in separate compositions, in which the composition or compositions do not contain an adjuvant.

Abstract: Compositions comprising a recombinant adenovirus of type Ad26 comprising a polynucleotide that encodes an antigen, kits of parts and methods of using these compositions for inducing an immune response in a subject are provided.

Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.

Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.

Abstract: Compositions, vaccines and methods using adenovirus vectors for priming and boosting vaccinations for inducing protective immunity against a Marburg virus infection are described.

Abstract: Compositions, vaccines and methods using adenovirus vectors for priming and boosting vaccinations for inducing protective immunity against a Marburg virus infection are described.

Abstract: Methods of inducing an immune response against human immunodeficiency virus (HIV) are described. In particular, methods of inducing an immune response against HIV by co-locally administering an immunogenically effective amount of an isolated HIV envelope (Env) polypeptide and an immunogenically effective amount of an adenovirus vector encoding an HIV antigen, e.g., Env antigen are described. The isolated HIV Env polypeptide and adenovirus vector can be administered in a single composition or in separate compositions, in which the composition or compositions do not contain an adjuvant.

Abstract: Provided herein are Modified Vaccinia Ankara (MVA) vectors and adenovirus vectors encoding HBV antigens. Also provided are methods of enhancing an immune response in a human subject by utilizing the MVA and adenovirus vectors encoding HBV antigens in a prime/boost regimen to the enhance the immune response in the human subject.

Abstract: Content transfer between nodes in a communications network is required in many situations. For example, between fixed nodes in a data center, between a fixed node such as a base station and a mobile node such as a mobile telephone and between mobile nodes themselves such as personal digital assistants. In an embodiment a content transfer process for use between nodes where one node knows the size of content to be transferred is described. For example, a file is divided into blocks to be sent between the nodes. A node receiving a block keeps a record of the received blocks and sends that record to the sending node at certain times. By controlling the times at which the records are sent the number of messages that need to be sent to transfer the records is low and the blocks are transferred in an efficient manner.

Abstract: The invention relates to a housing (1) for receiving at least one flat electrochemical cell (2), comprising two housing side walls (4) which are disposed substantially parallel to one another, wherein a flat cooling bracket (9) is disposed on at least one flat electrochemical cell (2). The flat cooling bracket (9) is preferably disposed substantially parallel to the flat electrochemical cell (2). The flat electrochemical cell (2) may also have a sealing seam (3) extending at least in some regions on the edge of said cell and, for each flat electrochemical cell (2) to be received, the housing side walls (4) disposed parallel to one another comprise, in the inner faces thereof that are facing one another, a pair of opposite notches (5) configured to receive the at least one sealing seam (3) of the respective flat electrochemical cell (2).

Abstract: An electrochemical cell is proposed having an electrical unit, a first frame part and a second frame part, wherein the electrical unit is clamped in the area of the clamping surfaces between the first frame part and the second frame part, characterized in that the electrical energy unit and the first frame part have shape features which match one another and engage in one another such that a relative position of the electrical unit with respect to the first frame part is at least substantially fixed, at least in a state in which the clamping assembly of the frame parts and the electrical unit is released. This allows the electrical unit to be prefixed in the first frame part before production of the clamping assembly, making it possible to prevent the electrical unit from being installed obliquely.

Abstract: In the case of a thermally conductive plate (1) having a network of flow channels (2), at least one inlet (3) and at least one outlet (4) for a fluid, the fluid channels are arranged such that a fluid which flows into the network of flow channels at the at least one inlet (3) can flow through an arrangement of zones (5) of the thermally conductive plate whose temperature is to be controlled, and can then flow out of the network of flow channels at the at least one outlet (4). The flow channels are arranged one above the other in at least two levels. The network of flow channels comprises a tree-like structure of distribution channels (6), which is arranged on at least one first level, which distribution channels (6) guide a fluid to zones (5) of the thermally conductive plate whose temperature is to be controlled, starting from the at least one inlet into the network of flow channels.

Abstract: An electrochemical cell comprises an electrode stack, at least one current conductor connected to the electrode stack, and a casing at least partially enclosing the electrode stack, wherein the at least one current conductor extends at least partially out of the casing. At least one heating device is integrated into the casing of the electrochemical cell which has at least one preferably areal heating zone extending at least over a sub-region of the casing.

Abstract: The invention relates to an electrical energy storage cell comprising an electrical energy storage structure, a housing which receives the electrical energy storage structure and surrounds it in a sealed manner, and at least two contact elements which are accessible outside the housing for the electrical connection to electrode regions of the electrical energy storage structure. At least one heat conducting element, which is constructed separately from the electrical energy storage structure and is designed and equipped to absorb heat from the electrical energy storage structure and to release heat to outside of the housing, is disposed inside the housing. The invention also relates to an electrical energy storage device comprising an array of electrical energy storage cells.

Abstract: The invention relates to a cooling element, which is designed and equipped in particular to be disposed between electrochemical energy storage cells, comprising a heat exchanger structure through which a heat transfer medium can flow and which is formed at least substantially of two film layers or film layer structures, the opposing surfaces of which are placed against one another and which are connected at junctures within the surfaces, wherein the junctures define cavities between the surfaces, wherein the heat transfer medium can be conducted through said cavities.

Abstract: Content discovery and content transfer between mobile communications nodes is often required, for example, to synchronize maps, traffic hot spot information and the like for vehicle mounted satellite navigation devices, pedestrian hand-held personal digital assistants and other mobile communications nodes. In an embodiment, content discovery processes using a tree-based data structure for transferring data between two mobile communication nodes is described.

Abstract: The present invention relates to an energy store device, comprising a plurality of cooling channels, which are disposed in a plane spaced apart from each other substantially parallel to each other and designed for a cooling fluid to flow through them, at least one collection box, which is disposed in the plane with and substantially perpendicular to the plurality of cooling channels and is connected thereto to take up the cooling fluid therefrom or release it therein, and with a stack composed of a plurality of electrochemical energy store units, which are disposed such that between two adjacent cooling channels of the plurality of cooling channels at least one energy store unit from the plurality of electrochemical energy store units is disposed, respectively.

Abstract: Content discovery and content transfer between mobile communications nodes is often required, for example, to synchronize maps, traffic hot spot information and the like for vehicle mounted satellite navigation devices, pedestrian hand-held personal digital assistants and other mobile communications nodes. In an embodiment, content discovery processes using a tree-based data structure for transferring data between two mobile communication nodes is described.

Abstract: Content discovery and content transfer between mobile communications nodes is often required, for example, to synchronize maps, traffic hot spot information and the like for vehicle mounted satellite navigation devices, pedestrian hand-held personal digital assistants and other mobile communications nodes. In an embodiment, content discovery processes using data structures designed in particular ways and sent using a single packet enable nodes to identify files to be transferred whilst keeping overheads down. In an embodiment a first and a second data structure are used, each being formed from slightly different information about a subset of the files to be synchronized. In another embodiment a single tree-based data structure is used. A process for transferring data between two mobile communications nodes is also described.