Patents by Inventor Christine Power

Christine Power has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies specific for MMP9
    Patent number: 10364296
    Abstract: The present invention relates to new proteins that bind to MMP9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the MMP9 binding proteins according to the invention are able to neutralize MMP9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers. In particular, the MMP9 binding proteins according to the invention are useful in diagnosis of MMP9-related disorders.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: July 30, 2019
    Assignees: CALYPSO BIOTECH SA, MERCK PATENT GMBH
    Inventors: Yolande Chvatchko Missotten, Laurence Goffin, Olivier Leger, Steven M. Dunn, Christine Power, Kinsey Maundrell
  • ANTIBODIES SPECIFIC FOR MMP9
    Publication number: 20170233495
    Abstract: The present invention relates to new proteins that bind to MMP9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the MMP9 binding proteins according to the invention are able to neutralize MMP9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers. In particular, the MMP9 binding proteins according to the invention are useful in diagnosis of MMP9-related disorders.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 17, 2017
    Inventors: YOLANDE CHVATCHKO MISSOTTEN, LAURENCE GOFFIN, OLIVIER LEGER, STEVEN M. DUNN, CHRISTINE POWER, KINSEY MAUNDRELL
  • Monoclonal antibody directed against CXCR5
    Patent number: 9534054
    Abstract: The invention relates to monoclonal antibodies against human CXCR5 and to their use in the treatment of autoimmune or inflammatory diseases, as well as cancers.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: January 3, 2017
    Assignee: ARES TRADING S.A.
    Inventors: Christine Power, Olivier Leger, Paul Bradfield, Horacio G. Nastri, Christel Iffland, Qi An
  • MONOCLONAL ANTIBODY DIRECTED AGAINST CXCR5
    Publication number: 20160115235
    Abstract: The invention relates to monoclonal antibodies against human CXCR5 and to their use in the treatment of autoimmune or inflammatory diseases, as well as cancers.
    Type: Application
    Filed: April 30, 2014
    Publication date: April 28, 2016
    Inventors: CHRISTINE POWER, OLIVIER LEGER, PAUL BRADFIELD
  • Treatment of fibrotic disease
    Patent number: 8283307
    Abstract: The invention relates to the use of INSP035 for treatment and/or prevention of fibrotic diseases, in particular of scleroderma.
    Type: Grant
    Filed: September 7, 2004
    Date of Patent: October 9, 2012
    Assignee: Merck Serono SA
    Inventors: Christine Power, Yan Lavrovsky
  • vWFA and/or ANTIG domain containing proteins
    Patent number: 8222371
    Abstract: Proteins (INSP141, INSP142, INSP143, and INSP144) identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease are described.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: July 17, 2012
    Assignee: Ares Trading S.A.
    Inventors: Mark Douglas Davies, David Michalovich, Melanie Yorke, Christine Power
  • Cell surface glycoprotein
    Patent number: 8124748
    Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: February 28, 2012
    Assignee: Ares Trading S.A.
    Inventors: Stephen Fitzgerald, Richard Fagan, Jadwiga Bienkowska, Christine Power, Melanie Yorke-Smith
  • TREATMENT AND/OR PREVENTION OF CANCER AND/OR ARTHRITIS
    Publication number: 20100303760
    Abstract: The invention relates to the use of INSP163 for treatment and/or prevention of cancer and/or musculoskeletal/connective tissue disorder, in particular of lung cancer and/or osteoarthritis. Combinations of INSP163 with an interferon, a TNF antagonist or a further anti-cancer or anti-arthritis agent are also within the present invention.
    Type: Application
    Filed: April 20, 2006
    Publication date: December 2, 2010
    Applicant: Laboratoires Serono SA
    Inventors: Christine Power, Melanie Yorke-Smith
  • Soluble CD164 polypeptides
    Patent number: 7803910
    Abstract: The present invention relates to sCD164 variants and therapeutic uses thereof, in particular for treating or preventing inflammatory or autoimmune disorders.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: September 28, 2010
    Assignee: Merck Serono S.A.
    Inventors: Gabriela Saborio, Christine Power, Amanda Proudfoot
  • Method of treatment comprising administration of a cytokine antagonist molecule
    Patent number: 7803383
    Abstract: This invention relates to novel uses of a protein sequence (INSP052EC), herein identified as an immunoglobulin domain-containing cell surface recognition, in the diagnosis, prevention and treatment of diseases, in particular those related to the excessive expression and/or secretion of cytokines.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: September 28, 2010
    Assignee: Ares Trading S.A.
    Inventors: Richard Joseph Fagan, Andrew Robert Davids, Christopher Benjamin Phelps, Christine Power, Ursula Boschert, Yolande Chvatchko
  • REELER DOMAIN CONTAINING PROTEIN
    Publication number: 20100196349
    Abstract: This invention relates to protein INSP 171, herein identified as containing a Reeler domain, and to the use of this protein and the nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: December 4, 2006
    Publication date: August 5, 2010
    Applicant: ARES TRADING S.A.
    Inventors: Christine Power, Melanie Yorke-Smith, Richard Fagan, Tania Rodrigues, Dave Michalovich
  • Isolated INSP 163 protein
    Patent number: 7700724
    Abstract: This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a C1q-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: April 20, 2010
    Assignee: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke, Jadwiga Bienkowska
  • CXC-chemokine antagonists isolated from
    Patent number: 7670802
    Abstract: A novel CXC-chemokine binding protein is cloned from the salivary glands of Rhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory and immuno-modulatory compounds and in the treatment or prevention of CXC-chemokine-related diseases.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: March 2, 2010
    Assignee: Merck Serono SA
    Inventors: Amanda Proudfoot, Christine Power
  • Cystine-Knot Fold Cytokine
    Publication number: 20100048467
    Abstract: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: January 12, 2006
    Publication date: February 25, 2010
    Applicant: ARES TRADING S.A.
    Inventors: Mark Douglas Davies, Christopher Benjamin Phelps, Richard Joseph Fagan, Christine Power, Melanie Yorke, Mark Ibberson, Yan Lavrovsky
  • Uses of a chemokine receptor able to bind to MCP-1, MIP-1? and/or RANTES
    Patent number: 7655425
    Abstract: A chemokine receptor binds to MCP-1, MIP-1? and/or RANTES. It can be used in screening for agents which act as antagonists to MCP-1, MIP-1? and/or RANTES. Such agents may be useful in treating various disorders, including allergies, atheromas and diseases mediated by viruses. They may also be useful in preventing graft rejection and in protecting stem cells from potentially damaging effects of chemotherapy.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: February 2, 2010
    Assignee: Glaxo Group Limited
    Inventors: Timothy N. C. Wells, Christine A. Power
  • Method for treating liver cirrhosis or interstitial pulmonary fibrosis
    Patent number: 7655628
    Abstract: The invention relates to the use of SARP-1 for the preparation of a medicament for the treatment and/or prevention of scleroderma, in particular of systemic sclerosis.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: February 2, 2010
    Assignee: Merck Serono SA
    Inventors: Christine Plater-Zyberk, Christine Power, Jacques Colinge
  • Defensin Proteins
    Publication number: 20090324562
    Abstract: This invention relates to the novel proteins, termed INSP108 and INSP109, herein identified as members of the defensin family of proteins and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: June 30, 2009
    Publication date: December 31, 2009
    Inventors: Richard Joseph Fagan, David Michalovich, Simon John White, Christine Power, Melanie Yorke
  • Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease
    Patent number: 7638480
    Abstract: The invention relates to the use of osteoprotegerin for treatment and/or prevention of fibrotic diseases, in particular of scleroderma.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: December 29, 2009
    Assignee: Laboratoires Serono SA
    Inventors: Christine Power, Christine Plater-Zyberk
  • CC-chemokine binding tick proteins
    Patent number: 7635576
    Abstract: A novel CC-chemokine binding protein is isolated from the saliva of Rhipicephalus sanguineus. Compounds prepared in accordance with the present invention can be used as anti-inflammatory compounds and in the treatment or prevention of CC-chemokine-related diseases.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: December 22, 2009
    Assignee: Merck Serono SA
    Inventors: Amanda Proudfoot, Christine Power, Achim Frauenschuh
  • Cytokine antagonist molecules
    Patent number: 7622555
    Abstract: This invention relates to a novel protein (INSP052), herein identified as an immunoglobulin domain-containing cell surface recognition molecule and to the use of this proteins and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease. The invention also relates to the identification of the extracellular domain of INSP052.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: November 24, 2009
    Assignee: Ares Trading S.A.
    Inventors: Andrew Robert Davids, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Yolande Chvatchko, Ursula Boschert