Patents by Inventor Christine Santos

Christine Santos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metabolic engineering for microbial production of terpenoid products
    Patent number: 10480015
    Abstract: The invention relates to methods and bacterial strains for making terpene and terpenoid products, the bacterial strains having improved carbon pull through the MEP pathway and to a downstream recombinant synthesis pathway.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: November 19, 2019
    Assignee: MANUS BIO INC.
    Inventors: Ajikumar Parayil Kumaran, Ryan Lim, Jason Donald, Hsien-Chung Tseng, Christine Santos, Ryan Philippe
  • METABOLIC ENGINEERING FOR MICROBIAL PRODUCTION OF TERPENOID PRODUCTS
    Publication number: 20180216137
    Abstract: The invention relates to methods and bacterial strains for making terpene and terpenoid products, the bacterial strains having improved carbon pull through the MEP pathway and to a downstream recombinant synthesis pathway.
    Type: Application
    Filed: January 26, 2018
    Publication date: August 2, 2018
    Inventors: Ajikumar Parayil KUMARAN, Ryan LIM, Jason DONALD, Hsien-Chung TSENG, Christine SANTOS, Ryan PHILIPPE
  • Strains for the production of flavonoids from glucose
    Patent number: 9181539
    Abstract: The invention relates to the production of flavonoids and flavonoid precursors in cells through recombinant expression of tyrosine ammonia lyase (TAL), 4-coumarate:CoA ligase (4CL), chalcone synthase (CHS), and chalcone isomerase (CHI).
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: November 10, 2015
    Assignees: Massachusetts Institute of Technology, The Research Foundation of State University of New York
    Inventors: Gregory Stephanopoulos, Christine Santos, Mattheos Koffas
  • Mutations and genetic targets for enhanced L-tyrosine production
    Patent number: 8735132
    Abstract: The invention relates to identification of mutations and genetic targets for enhanced L-tyrosine production, and bacterial strains capable of L-tyrosine production.
    Type: Grant
    Filed: May 5, 2011
    Date of Patent: May 27, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Christine Santos, Gregory Stephanopoulos
  • CHROMOSOMAL DNA INTEGRATION METHOD
    Publication number: 20120329115
    Abstract: The present disclosure relates to methods of integrating recombinant polynucleotides into genomes of unicellular organisms. In particular, the present disclosure relates to the modified unicellular organisms that contain integrated recombinant polynucleotides in their genomes and methods for production of commodity chemicals by the use of such organisms.
    Type: Application
    Filed: December 21, 2011
    Publication date: December 27, 2012
    Applicant: Bio Architecture Lab, Inc.
    Inventors: Christine SANTOS, Yasuo Yoshikuni
  • STRAINS FOR THE PRODUCTION OF FLAVONOIDS FROM GLUCOSE
    Publication number: 20120034661
    Abstract: The invention relates to the production of flavonoids and flavonoid precursors in cells through recombinant expression of tyrosine ammonia lyase (TAL), 4-coumarate:CoA ligase (4CL), chalcone synthase (CHS), and chalcone isomerase (CHI).
    Type: Application
    Filed: May 5, 2011
    Publication date: February 9, 2012
    Applicants: The Research Foundation of State University of New York, Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Christine Santos, Mattheos Koffas
  • MUTATIONS AND GENETIC TARGETS FOR ENHANCED L-TYROSINE PRODUCTION
    Publication number: 20110300588
    Abstract: The invention relates to identification of mutations and genetic targets for enhanced L-tyrosine production, and bacterial strains capable of L-tyrosine production.
    Type: Application
    Filed: May 5, 2011
    Publication date: December 8, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Christine Santos, Gregory Stephanopoulos