Abstract: An apparatus including tubing sets, a modular constraint assembly, and methods of use are described for deliver a therapeutic medication to a patient, the apparatus can have a controller and a sensor. The controller is configured to receive data from the sensor, and to start and stop delivery of the therapeutic medication to the patient in response to data received from the sensor. In addition, apparatus, systems and methods are disclosed, which are configured to deliver a therapeutic medication to a patient. The apparatus, system and methods use a reservoir, a patient interface, a tubing set, a modular constraint assembly connected to the tubing sets, and a fluid pump, and the components are configured to provide a calibrated flow rate based upon specific characteristics of the therapeutic medications passing through and internal lumen of the tubing set.

Abstract: An apparatus for use with tubing sets operatively connected to a medication deliver device, where the apparatus constricts fluid flow within the tubing are described for deliver a therapeutic medication to a patient, the apparatus operatively engages an outside surface of the tubing set causing compression of the tubing and reducing an inner diameter of the tubing.

Abstract: A micro dosing device is presented for delivering a metered dose of a therapeutic fluid having a dosing unit with a dosing chamber, a connector unit at a distal end for fluidly connecting a medicament container to the dosing chamber, a connector unit at a proximal end for fluidly connecting the dosing chamber to a medicament delivery member, and an activation mechanism, wherein the dosing chamber is configured to receive and therapeutic fluid. Further, the micro dosing device can have a dosing mechanism which provides an exactly metered dose of fluid to be expelled by the medicament delivery member, when the activation mechanism is triggered by a user.

Abstract: An apparatus including tubing sets, a modular constraint assembly, and methods of use are described for deliver a therapeutic medication to a patient, the apparatus can have a controller and a sensor. The controller is configured to receive data from the sensor, and to start and stop delivery of the therapeutic medication to the patient in response to data received from the sensor. In addition, apparatus, systems and methods are disclosed, which are configured to deliver a therapeutic medication to a patient. The apparatus, system and methods use a reservoir, a patient interface, a tubing set, a modular constraint assembly connected to the tubing sets, and a fluid pump, and the components are configured to provide a calibrated flow rate based upon specific characteristics of the therapeutic medications passing through and internal lumen of the tubing set.

Abstract: A device (1) for dispensing a substance to a patient comprising a cylindrical first container (2) containing the substance and a second container (3) containing a liquid. The device further comprises an injection device (4) and transfer mechanism (5) for transferring the liquid from the second container (3) to the first container (2) and from the first container (2) to the injection device (4). The first container (2) has a connection element (7) and a plunger (9) that can be moved between the first (6) and second ends (8). By moving the plunger (9) towards the first end (6), liquid contained therein can be dispensed via the injection device (4). The injection device (4) comprises a piercing cannula (15) and an indwelling cannula (16). In an initial position, a distal end region of the piercing cannula (15) extends coaxially in the interior of the indwelling cannula (16).

Abstract: An injection device for subcutaneous delivery of fluid which comprises a puncture cannula and an indwelling cannula. In a starting position, a distal end region of the puncture cannula runs coaxially inside the indwelling cannula. The device comprises displaceably mounted first and second runners. The first runner is connected to the puncture cannula and the second runner to the indwelling cannula. A control element is movable over a predefined control area. The control element is configured such that, in a first part of the control area, the control element effects an equidirectional displacement of the first and the second runners, and hence fitting of the indwelling cannula and, in a second part of the control area, effects blocking of the second runner, and hence holding of the indwelling cannula in a dwell position, and return of the first runner and withdrawal of the puncture cannula into an end position.

Abstract: A device and a method for dispensing at least one substance to a patient is presented where the device has a movable first container containing a first substance having a first piston with a first piston rod, a movable second container containing a second substance having a second piston with a second piston rod, an injection device, and a conduit device for guiding the contents of the second container to the first container and the contents of the first container to the injection device, wherein the first and the second piston are each movable via at least one pre-tensioned spring element. A free end of the first piston rod and a free end of the second piston rod are releasably held by a common holding component, and the common holding component is designed in such a way that a movement of the common holding component results in a successive release of the first piston rod and the second piston rod.

Abstract: A device (1) for dispensing a substance to a patient comprising a cylindrical first container (2) containing the substance and a second container (3) containing a liquid. The device further comprises an injection device (4) and transfer mechanism (5) for transferring the liquid from the second container (3) to the first container (2) and from the first container (2) to the injection device (4). The first container (2) has a connection element (7) and a plunger (9) that can be moved between the first (6) and second ends (8). By moving the plunger (9) towards the first end (6), liquid contained therein can be dispensed via the injection device (4). The injection device (4) comprises a piercing cannula (15) and an indwelling cannula (16). In an initial position, a distal end region of the piercing cannula (15) extends coaxially in the interior of the indwelling cannula (16).

Abstract: A dispensing device (1) for dispensing a fluid, preferably an injection syringe. The device comprises a main body (2) which has a longitudinal axis (A) and has a receiving space (3) for receiving the fluid, and a connection channel (4) communicates with the receiving space. The connection channel opens on a valve face (5) of the main body. The device comprises a movable flow control element (6) arranged on the main body. The flow control element has one or more flow channels (7) which open on a valve face (8) of the flow control element. The connection channel of the main body and the flow channels of the flow control element are fluidically connected to each other by relative movement of main body and flow control element. A sealing element (10) is arranged between the valve face of the main body and the valve face of the flow control element.

Abstract: An injection device for subcutaneous delivery of fluid which comprises a puncture cannula and an indwelling cannula. In a starting position, a distal end region of the puncture cannula runs coaxially inside the indwelling cannula. The device comprises displaceably mounted first and second runners. The first runner is connected to the puncture cannula and the second runner to the indwelling cannula. A control element is movable over a predefined control area. The control element is configured such that, in a first part of the control area, the control element effects an equidirectional displacement of the first and the second runners, and hence fitting of the indwelling cannula and, in a second part of the control area, effects blocking of the second runner, and hence holding of the indwelling cannula in a dwell position, and return of the first runner and withdrawal of the puncture cannula into an end position.

Abstract: A dispensing device (1) for dispensing a fluid, preferably an injection syringe. The device comprises a main body (2) which has a longitudinal axis (A) and has a receiving space (3) for receiving the fluid, and a connection channel (4) communicates with the receiving space. The connection channel opens on a valve face (5) of the main body. The device comprises a movable flow control element (6) arranged on the main body. The flow control element has one or more flow channels (7) which open on a valve face (8) of the flow control element. The connection channel of the main body and the flow channels of the flow control element are fluidically connected to each other by relative movement of main body and flow control element. A sealing element (10) is arranged between the valve face of the main body and the valve face of the flow control element.