Patents by Inventor Christoph P. Saager

Christoph P. Saager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing cartilage tissue and implants for repairing enchondral and osteochondral defects as well as arrangement for carrying out the method
    Patent number: 6387693
    Abstract: Cartilage tissue and implants comprising tissue are produced in vitro starting from cells having the ability to form an extracellular cartilage matrix. Such cells are brought into a cell space (1) and are left in this cell space for producing an extracellular cartilage matrix. The cells are brought into the cell space to have a cell density of ca. 5×107 to 109 cells per cm3 of cell space. The cell space (1) is at least partly separated from a culture medium space (2) surrounding the cell space by means of a semi-permeable wall (3) or by an open-pore wall acting as convection barrier. The open-pore wall can be designed as a plate (7) made of a bone substitute material and constituting the bottom of the cell space (1). The cells settle on such a plate (7) and the cartilage tissue growing in the cell space (1).
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: May 14, 2002
    Assignee: Sulzer Orthopedics Ltd.
    Inventors: Franz Rieser, Werner Muller, Pedro Bittmann, Pierre Mainil-Varlet, Christoph P. Saager
  • Method for producing cartilagetissue and implants for repairing encholndral and osteochondral defects as well as arrangement for carrying out the method
    Publication number: 20010014473
    Abstract: Cartilage tissue and implants comprising tissue are produced in vitro starting from cells having the ability to form an extracellular cartilage matrix. Such cells are brought into a cell space (1) and are left in this cell space for producing an extracellular cartilage matrix. The cells are brought into the cell space to have a cell density of ca. 5×107 to 109 cells per cm3 of cell space. The cell space (1) is at least partly separated from a culture medium space (2) surrounding the cell space by means of a semi-permeable wall (3) or by an open-pore wall acting as convection barrier. The open-pore wall can be designed as a plate (7) made of a bone substitute material and constituting the bottom of the cell space (1). The cells settle on such a plate (7) and the cartilage tissue growing in the cell space (1).
    Type: Application
    Filed: April 18, 2001
    Publication date: August 16, 2001
    Applicant: Sulzer Orthopedics Ltd.
    Inventors: Franz Rieser, Werner Muller, Pedro Bittmann, Pierre Mainil-Varlet, Christoph P. Saager
  • Method for making cartilage and implants
    Patent number: 6242247
    Abstract: Cartilage tissue and implants comprising cartilage tissue are produced in vitro starting from cells having the ability to form an extracellular cartilage matrix. Such cells are brought into a cell space (1) and are left in this cell space for producing an extracellular cartilage matrix. The cells are brought into the cell space to have a cell density of ca. 5×107 to 109 cells per cm3 of cell space. The cell space (1) is at least partly separated from a culture medium space (2) surrounding the cell space by a semi-permeable wall (3) or by an open-pore wall acting as convection barrier. The open-pore wall can be designed as a plate (7) made of a bone substitute material and constituting the bottom of the cell space (1).
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: June 5, 2001
    Assignee: Sulzer Orthopedics Ltd.
    Inventors: Franz Rieser, Werner Muller, Pedro Bittmann, Pierre Mainil-Varlet, Christoph P. Saager