Patents by Inventor Christoph Rehfuess

Christoph Rehfuess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-HER2 vaccine based upon AAV derived multimeric structures
    Patent number: 9821043
    Abstract: The present invention relates to parvovirus mutated structural proteins comprising insertions of mimotopes of a HER2, compositions, multimeric structures, medicaments and vaccines comprising the same, nucleic acids, expression cassettes, constructs, vectors and cells comprising the nucleic acids, methods of preparing the structural proteins and methods of inducing a B-cell response or of treating a HER2-related disease.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: November 21, 2017
    Assignee: Medigene AG
    Inventors: Uwe Michaelis, Erika Jensen-Jarolim, Christoph Rehfuess, Margit Weghofer
  • ANTI-HER2 VACCINE BASED UPON AAV DERIVED MULTIMERIC STRUCTURES
    Publication number: 20150238585
    Abstract: The present invention relates to parvovirus mutated structural proteins comprising insertions of mimotopes of a HER2, compositions, multimeric structures, medicaments and vaccines comprising the same, nucleic acids, expression cassettes, constructs, vectors and cells comprising the nucleic acids, methods of preparing the structural proteins and methods of inducing a B-cell response or of treating a HER2-related disease.
    Type: Application
    Filed: September 14, 2012
    Publication date: August 27, 2015
    Inventors: Uwe Michaelis, Erika Jensen-Jarolim, Christoph Rehfuess, Margit Weghofer
  • Inhibitors of Fatty Acid Oxidation for Prophylaxis and Treatment of Diseases Related to Mitochondrial Dysfunction
    Publication number: 20110212072
    Abstract: Described are a method and a composition for preventing and/or treating a disease related to mitochondrial dysfunction by inhibiting the fatty acid oxidation of one or more cells of an organism. Particularly, the fatty acid oxidation is inhibited by inhibiting the expression and/or activity of the enzyme Camitin-Palmitoyl-Transferase-1 (CPT-1) by means of an arylalkyl- or arlyoxyalkyl-substitued oxirane carboxylic acid or pharmaceutically acceptable salts and derivatives of the arylalkyl-substituted oxirane carboxylic acid.
    Type: Application
    Filed: April 19, 2011
    Publication date: September 1, 2011
    Applicant: MediGene AG
    Inventors: Thomas Henkel, Christoph Rehfuess
  • Inhibitors of fatty acid oxidation for prophylaxis and treatment of diseases related to mitochondrial dysfunction
    Publication number: 20100034796
    Abstract: Described are a method and a composition for preventing and/or treating a disease related to mitochondrial dysfunction by inhibiting the fatty acid oxidation of one or more cells of an organism. Particularly, the fatty acid oxidation is inhibited by inhibiting the expression and/or activity of the enzyme Carnitin-Palmitoyl-Transferase-1 (CPT-1) by means of an arylalkyl- or arlyoxyalkyl-substitued oxirane carboxylic acid or pharmaceutically acceptable salts and derivatives of the arylalkyl-substituted oxirane carboxylic acid.
    Type: Application
    Filed: June 29, 2009
    Publication date: February 11, 2010
    Applicant: MediGene AG
    Inventors: Thomas Henkel, Christoph Rehfuess
  • Topical use of cytokines and chemokines for the treatment of viral or mykotic skin diseases or tumoral diseases
    Publication number: 20050008614
    Abstract: The invention relates to the use of at least one cytokine and/or chemokine in the production of a topically acting medicament for treating viral and/or mykotic skin diseases and/or tumoral diseases.
    Type: Application
    Filed: November 7, 2002
    Publication date: January 13, 2005
    Inventors: John Nieland, Christoph Rehfuess
  • Inhibitors of fatty acid oxidation for prophylaxis and treatment of diseases related to mitochondrial dysfunction
    Publication number: 20050004173
    Abstract: Described are a method and a composition for preventing and/or treating a disease related to mitochondrial dysfunction by inhibiting the fatty acid oxidation of one or more cells of an organism. Particularly, the fatty acid oxidation is inhibited by inhibiting the expression and/or activity of the enzyme Carnitin-Palmitoyl-Transferase-1 (CPT-1) by means of an arylalkyl- or arlyoxyalkyl-substitued oxirane carboxylic acid or pharmaceutically acceptable salts and derivatives of the arylalkyl-substituted oxirane carboxylic acid.
    Type: Application
    Filed: April 26, 2004
    Publication date: January 6, 2005
    Inventors: Thomas Henkel, Christoph Rehfuess