Abstract: Provided herein are uses of the compounds for the treatment of various indications, including prostate cancer and Kennedy's disease.

Abstract: A seeder element of an agricultural machine includes a seed distribution element and a tamping device. The tamping device is arranged behind an outlet of the seed distribution element in a direction of advance at work of the seeder element. The tamping device includes an adjustment device and a tamping element. The tamping element exerts a tamping force on the ground in at least one work position of the adjustment device. The at least one work position of the adjustment device is a load-relieving position in which the adjustment device exerts, on the tamping element, a load-relieving stress that counters the weight of the tamping element.

Abstract: Apparatus for providing optical radiation (15), which apparatus comprises an optical input (13), a coupler (2), a first semiconductor amplifier (3), a controller (4), a preamplifier (61), a power amplifier (62) and an output fibre (5), wherein: the optical input (13) is for receiving input optical radiation (14); the optical input (13) is connected in series to the coupler (2), the first semiconductor amplifier (3), the preamplifier (61), the power amplifier (62), and the output fibre (5); the apparatus being characterized in that: the first semiconductor amplifier (3) comprises a waveguide (6) having a low reflecting facet (8); the first semiconductor amplifier (3) is in a double pass configuration such that the low reflecting facet (8) is connected to both the optical input (13) and the preamplifier (61) via the coupler (2); and the controller (4) is configured to cause the waveguide (6) of the first semiconductor amplifier (3) to operate in saturation thereby enabling the first semiconductor amplifier (3)

Abstract: The invention relates to a scraper device for a disc of an agricultural machine comprising: a first outer scraper element comprising a suitable first scraper portion intended to rest against the outer surface of the first disc and a suitable first coupling portion intended to be coupled to a chassis of the agricultural machine; a first inner scraper element comprising a suitable second scraper portion intended to rest against the inner surface of the first disc and a suitable second coupling portion intended to be coupled to the first coupling portion of the first outer scraper element; the first inner scraper element being swivel-mounted with respect to the first outer scraper element around a second rotation axis; characterized in that it comprises: a resetting means connected to the second coupling portion to cause a rotational movement of the first inner scraper element along the second rotation axis, so as to press the second scraper portion against the inner surface of the first disc and so as to ca

Abstract: An apparatus for laser processing a material including an optical fibre, at least one squeezing mechanism, and a lens. The optical fibre is a multimode optical fibre in which laser radiation propagates in a first optical mode and in a second optical mode. The squeezing mechanism includes at least one periodic surface defined by a pitch. The periodic surface is located adjacent to the optical fibre. The pitch couples the first and second optical modes together. The first optical mode is defined by a first mode order. The second optical mode is defined by a second mode order which is higher than the first mode order. The squeezing mechanism squeezes the periodic surface and optical fibre together with a squeezing force thereby coupling the first optical mode to the second optical mode.

Abstract: Apparatus for laser processing a material (11), which apparatus comprises a laser (1), an optical fibre (2), and a coupler (125), wherein: the laser (1) is connected to the optical fibre (2); the optical fibre (2) is such that laser radiation (13) is able to propagate along the optical fibre (2) in a first optical mode (21) having a first mode order (24), a second optical mode (22) having a second mode order (25), and a third optical mode (23) having a third mode order (26); the third mode order (26) is higher than the second mode order (25); and the second mode order (25) is higher than the first mode order (24); the apparatus being characterized in that: the coupler (125) is configured to switch laser radiation propagating in the first optical mode (21) to the laser radiation propagating in the second order mode (22); and the coupler (125) is configured to switch the laser radiation propagating in the second optical mode (22) to laser radiation propagating in the third order mode (23).

Abstract: An agricultural product burying unit for an agricultural machine, configured so as to be mounted in a fixed manner relative to the agricultural machine, includes: a reference device, and a burying device. The reference device is configured to rest on the ground in the work configuration and form a depth positioning reference for the burying device. The burying device is configured to bury an agricultural product in the work configuration. The reference device is configured to be mounted in an articulated manner directly on a reference which is fixed relative to the agricultural machine. The reference device is configured to weigh on the burying device in the work configuration, thereby forming a first device of applying a bearing force on the burying device.

Abstract: A working element is mounted on an agricultural machine having a deformable connecting structure including upper arms and lower arms. The connecting structure includes a system for adjusting the down-pressure having a movable mechanism and a reference member. The mechanism includes a lever and a resilient member that are articulated about a first axis. The mechanism allows an engaged state in which it is held against the reference member in a working position, subjecting the working element to a down-pressure, and an adjusting state in which it is movable about a lower axis with respect to the reference member. The mechanism includes a second axis about which the lever is pivotable in an intermediate state.

Abstract: Apparatus for laser processing a material (11), which apparatus comprises an optical fibre (2), at least one squeezing mechanism (3), and a lens (4), wherein: the optical fibre (2) is a multimode optical fibre; the optical fibre (2) is such that laser radiation (13) is able to propagate along the optical fibre (2) in a first optical mode (21) and in a second optical mode (22); the squeezing mechanism (3) comprises at least one periodic surface (6) defined by a pitch (7); and the periodic surface (6) is located adjacent to the optical fibre (2); and the apparatus is characterized in that: the pitch (7) couples the first optical mode (21) and the second optical mode C(22) together; the first optical mode (21) is defined by a first mode order (24), and the second optical mode (22) is defined by a second O mode order (25) which is higher than the first mode order (24); the squeezing mechanism (3) is configured to squeeze the periodic surface (6) and the optical fibre (2) together with a squeezing force (12), ther

Abstract: A seeder element of an agricultural machine includes a seed distribution element and a tamping device. The tamping device is arranged behind an outlet of the seed distribution element in a direction of advance at work of the seeder element. The tamping device includes an adjustment device and a tamping element. The tamping element exerts a tamping force on the ground in at least one work position of the adjustment device. The at least one work position of the adjustment device is a load-relieving position in which the adjustment device exerts, on the tamping element, a load-relieving stress that counters the weight of the tamping element.

Abstract: Apparatus for providing optical radiation (15), which apparatus comprises an optical input (13), a coupler (2), a first semiconductor amplifier (3), a controller (4), a preamplifier (61), a power amplifier (62) and an output fibre (5), wherein: the optical input (13) is for receiving input optical radiation (14); the optical input (13) is connected in series to the coupler (2), the first semiconductor amplifier (3), the preamplifier (61), the power amplifier (62), and the output fibre (5); the apparatus being characterized in that: the first semiconductor amplifier (3) comprises a waveguide (6) having a low reflecting facet (8); the first semiconductor amplifier (3) is in a double pass configuration such that the low reflecting facet (8) is connected to both the optical input (13) and the preamplifier (61) via the coupler (2); and the controller (4) is configured to cause the waveguide (6) of the first semiconductor amplifier (3) to operate in saturation thereby enabling the first semiconductor amplifier (3)

Abstract: A working element is mounted on an agricultural machine having a deformable connecting structure including upper arms and lower arms. The connecting structure includes a system for adjusting the down-pressure having a movable mechanism and a reference member. The mechanism includes a lever and a resilient member that are articulated about a first axis. The mechanism allows an engaged state in which it is held against the reference member in a working position, subjecting the working element to a down-pressure, and an adjusting state in which it is movable about a lower axis with respect to the reference member. The mechanism includes a second axis about which the lever is pivotable in an intermediate state.

Abstract: Apparatus for providing optical radiation (1), which apparatus comprises a laser diode (2), a pulse generator (9), and a modulator (5), wherein: the pulse generator (9) is configured to emit picosecond pulses; the modulator (5) is configured to emit nanosecond pulses; the laser diode (2) has a first terminal (6) and a second terminal (7); the pulse generator (9) is connected to the first terminal (6); and the modulator (5) is configured to bias the laser diode (2) below a lasing threshold (8) of the laser diode (2), and the apparatus being characterized in that: the modulator (5) is connected to the second terminal (7); the pulse generator (9) comprises a semiconductor junction (32) connected to a differentiator (4); the semiconductor junction (32) is such that electric current flowing through the semiconductor junction (32) can be turned off more quickly than it can be turned on; and the differentiator (4) is such that a step change that occurs when the electric current flowing through the semiconductor junc

Abstract: An agricultural product burying unit for an agricultural machine, configured so as to be mounted in a fixed manner relative to the agricultural machine, the burying unit including a reference device, a burying device, the reference device being configured to rest on the ground in the work configuration and form a depth positioning reference for the burying device, the burying device being configured to bury an agricultural product in work configuration, the reference device being configured to be mounted in an articulated manner directly on a reference which is fixed relative to the agricultural machine, wherein the reference device is configured to weigh on the burying device in work configuration, the reference device forming a first device of applying a bearing force on the burying device.

Abstract: Apparatus for providing optical radiation (1), which apparatus comprises a laser diode (2), a pulse generator (9), and a modulator (5), wherein: the pulse generator (9) is configured to emit picosecond pulses; the modulator (5) is configured to emit nanosecond pulses; the laser diode (2) has a first terminal (6) and a second terminal (7); the pulse generator (9) is connected to the first terminal (6); and the modulator (5) is configured to bias the laser diode (2) below a lasing threshold (8) of the laser diode (2), and the apparatus being characterized in that: the modulator (5) is connected to the second terminal (7); the pulse generator (9) comprises a semiconductor junction (32) connected to a differentiator (4); the semiconductor junction (32) is such that electric current flowing through the semiconductor junction (32) can be turned off more quickly than it can be turned on; and the differentiator (4) is such that a step change that occurs when the electric current flowing through the semiconductor junc

Abstract: A frangible connector closure is provided for connection to a medication administration tube, and includes a tubular body portion having an open end configured for being connected to a supply of medication, and an opposite closed end. An elongate, rigid frangible member is disposed at the closed end and closes the end from fluid flow. The frangible member has a closure end and an opposite free end, and a longitudinal axis. In addition, the frangible member extends in an axial direction and has a member transverse dimension. The free end forms a finger portion extending in the axial direction and has a transverse dimension less than the member transverse dimension. The closure end of the frangible member is readily separable from the body portion by manual manipulation relative to the body portion when the frangible member is disposed inside the tube, for user-activated opening of the connector.

Abstract: A workshop for preparing aeroengines for shipping, the workshop including a station for fitting test and measurement mechanism on an engine, a mechanism for transporting the engine to test premises and for returning the engine to the workshop, a station for removing the test and measurement mechanism, a station for endoscopic inspection, a finishing station, and a shipping station. The engines are transported from one station to another by spreaders fastened on the engines and attached to hoists that are movable in translation along an overhead structure arranged in the workshop, each station being fitted with computer terminals for displaying and tracking the tasks to be performed on the engine in the corresponding station.

Abstract: The invention relates to a sensor arrangement for use in a sensor bearing with a magnetic ring (14) with multiple pole pairs, the sensor arrangement including at least three magnetic sensors (16) and to a sensor bearing using such a sensor arrangement. It is proposed that the at least three magnetic sensors (16) are encapsulated in a prefabricated package (17).

Abstract: A workshop for preparing aeroengines for shipping, the workshop including a station for fitting test and measurement mechanism on an engine, a mechanism for transporting the engine to test premises and for returning the engine to the workshop, a station for removing the test and measurement mechanism, a station for endoscopic inspection, a finishing station, and a shipping station. The engines are transported from one station to another by spreaders fastened on the engines and attached to hoists that are movable in translation along an overhead structure arranged in the workshop, each station being fitted with computer terminals for displaying and tracking the tasks to be performed on the engine in the corresponding station.