Abstract: The present invention is relative to an isolated nucleic acid molecule encoding a chimeric antigen receptor (CAR), wherein the CAR comprises an antibody or antibody fragment which includes a anti-IL-1RAP binding domain, polypeptides encoded by this nucleic acid molecule, isolated chimeric antigen receptor (CAR) molecule comprising such an antibody or antibody fragment, a vector comprising a nucleic acid molecule encoding a CAR, as well as a T cell comprising this vector. The present invention is also relative to the use of this T cell (autologous or allogeneic) expressing a CAR molecule to treat a proliferative disease in a mammal.

Abstract: A safety detector including a detection module configured for reading a control signal at the input, the detector including two supply terminals, a first control input and a first control output, a first safety output and a second safety output, and a first free terminal and a second free terminal, the detector including: a second control input connected to the first free terminal and a second control output connected to the second free terminal, and a test module configured for notably applying a first test sequence including a disabling of the first control output and a test of a start loop connected between the second control output and the first control input.

Abstract: A safety detector including a detection module configured for reading a control signal at the input, the detector including two supply terminals, a first control input and a first control output, a first safety output and a second safety output, and a first free terminal and a second free terminal, the detector including: a second control input connected to the first free terminal and a second control output connected to the second free terminal, and a test module configured for notably applying a first test sequence including a disabling of the first control output and a test of a start loop connected between the second control output and the first control input.

Abstract: A safety detector including a detection module configured for reading a control signal at the input, the detector including two supply terminals, a first control input and a first control output, a first safety output and a second safety output, and a first free terminal and a second free terminal, the detector including: a second control input connected to the first free terminal and a second control output connected to the second free terminal, and a test module configured for notably applying a first test sequence including a disabling of the first control output and a test of a start loop connected between the second control output and the first control input.

Abstract: Enclosure for electrical switching equipment including electrical control or display devices (21) supported on a wall (23) of the enclosure, being accessible from the outside, a processing or control unit (20) for these devices which is housed inside the enclosure, and an electrical interface device (1) between the devices (21) and the unit (20), the interface device (1) being composed of a housing (10) comprising a body (11) that houses a printed circuit board and encloses a row of connection terminals (30) and a connector (61) to connect the printed circuit board to the devices (21) and to unit (20) respectively, characterized in that the interface device (1) comprises an attachment part (12a) installed on the inside of the enclosure wall (23) close to the devices (21), and the terminals (30) on the device (1) are of the quick fit type.

Abstract: Enclosure for housing devices or components of electrical distribution or control and equipped on one of its faces with an enclosure aperture which can be closed and made watertight through a fixed or swiveling door. The door is designed to receive control elements of the devices housed inside the enclosure and has a closing panel (30). The closing panel (30) consists of substantially transparent panel and has mounting plates (70) which are adapted to carry the control elements and which include penetration apertures (75)for these elements, the contour of the penetration apertures forming a cutting template for control element apertures (80) for the closing panel (30)for the passage of the elements through the closing panel.