Patents by Inventor Christophe E. Redon

Christophe E. Redon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for measuring and quantifying DNA double-stranded breaks using gamma-H2AX and H2AX
    Patent number: 10809268
    Abstract: Disclosed are methods of measuring the amount of exposure of a host to a DNA double-stranded break (DSB)-causing agent by determining the ratio of the quantity of ?-H2AX to the quantity of total H2AX in a biological sample from the host as compared to the ratio of the quantity of ?-H2AX to the quantity of total H2AX in a positive control biological sample that has been exposed to a known amount of a DSB-causing agent. Related kits and methods of quantifying DSBs in a test biological sample are also disclosed.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: October 20, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Service
    Inventors: Christophe E. Redon, William M. Bonner, Yiping Zhang, Jiuping Ji
  • METHODS AND KITS FOR MEASURING AND QUANTIFYING DNA DOUBLE-STRANDED BREAKS USING GAMMA-H2AX AND H2AX
    Publication number: 20180003720
    Abstract: Disclosed are methods of measuring the amount of exposure of a host to a DNA double-stranded break (DSB)-causing agent by determining the ratio of the quantity of ?-H2AX to the quantity of total H2AX in a biological sample from the host as compared to the ratio of the quantity of ?-H2AX to the quantity of total H2AX in a positive control biological sample that has been exposed to a known amount of a DSB-causing agent. Related kits and methods of quantifying DSBs in a test biological sample are also disclosed.
    Type: Application
    Filed: February 1, 2016
    Publication date: January 4, 2018
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Service
    Inventors: Christophe E. Redon, William M. Bonner, Yiping Zhang, Jiuping Ji