Abstract: A molded article suitable for subsequent blow-molding into a final-shaped container. The article includes a neck portion; a gate portion; and a body portion extending between the neck portion and the gate portion, at least a majority of the body portion having an overall shape which is symmetric about a body axis extending longitudinally through a center of the body portion. The body portion includes an inner exterior layer and an outer exterior layer of a first polymeric material; and a core layer of a second polymeric material disposed between the inner exterior layer and the outer exterior layer. A radial thickness or a material of the core layer is selectively varied to govern non-uniform blow molding of the molded article into the final-shaped container.

Abstract: An M-output, where M>1, chirped pulse amplification chain that includes a stretcher of stretching factor tx_stretch, M amplifiers in cascade, M output compressors respectively placed at the output of each amplifier, wherein it comprises: a partially compressing device placed between the stretcher and the first amplifier, this partially compressing device having at least one partial compression factor, the one (or more than one) partial compression factor(s) being lower than tx_stretch, and an optical switch configured to receive a beam output from the stretcher and to direct it directly to the first amplifier of the cascade or to the partially compressing device depending on the output compressor chosen among the output compressors.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: Disclosed herein, amongst other things, is a method for converting a design of an original preform that is blow moldable to form a container into a converted preform having less molding material that is blow moldable to form the same container. The method includes retaining a neck finish and body of the original preform on the converted preform. The method further includes replacing the original base of the original preform with a converted base having an outer base surface that joins with an outer body surface of the body at an base split-line of the original base and that fits offset within an outer body surface of the original base, whereby the converted preform has a reduced total length, disregarding any gate vestige that may be formed thereon, relative to a total length of the original preform.

Abstract: The present invention relates to compound of formula (I) and their use for treating bacterial infections.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: Goniochromatic/light reflecting cosmetic compositions well suited for making up the skin, lips, hair or integuments, contain (a) at least one goniochromatic coloring agent suited for creating a goniochromatic colored background and (b) an amount of light reflective particles suited for creating highlight points that are visible to the naked eye, formulated into (c) a topically applicable, physiologically acceptable medium therefor.

Abstract: A compound of formula (I) or a racemate, an enantiomer, a diastereoisomer, a geometric isomer or a pharmaceutically acceptable salt thereof, and its use as antibacterial agent.

Abstract: The invention relates to the compounds (I) and their acids and bases salts: wherein: Formula (I) the dotted line indicates a double bond; X is N or C—R1 and Y is N or C—R2, X and Y not being simultaneously N; A is selected from the group consisting of phenyl, naphthyl and (5-11) membered monocyclic or bicyclic unsaturated cycle or heterocycle possibly substituted as defined in the application, and A can also comprise either a further (4-7) membered heterocycle, said heterocycle being a monocycle, fused, saturated or unsaturated, the polycyclic system then comprising up to 14 members and up to 5 heteroatoms selected from N, O and S; B is selected from the group of substituents as defined in the application, or B is a 4 or (6-10) membered mono or bicyclic saturated or unsaturated heterocycle containing 1-3 heteroatoms selected from N, O and S, linked by a carbon atom, and possibly substituted as defined in the application; R1 is Hydrogen or a substituent as defined in the application; R2 is Hydrogen or Halogen;

Abstract: A preform suitable for subsequent blow-molding into a final-shaped container comprises: a neck portion; a base portion; and a body portion extending between the neck portion and the base portion; the body portion being defined between an inner surface having a circular transverse cross-sectional shape and an outer surface also having a circular transverse cross-sectional shape, the inner and outer surfaces being non-concentric, such that a wall thickness of the body portion varies circumferentially around the preform. A preform handling apparatus for retrieving a preform from a mold comprises a take-off device having a preform carrier and a take-off device alignment mechanism for maintaining the preform carrier in alignment with a contact surface of a body portion of the preform regardless of any offset between a longitudinal axis of a cylindrical outer surface of the body portion and a longitudinal axis of a cylindrical inner surface of the body portion.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: Sterilizable multilayer material (1), in particular for packaging at least one device for medical use, comprising a non-thermofusible sheet (2) sandwiched between two lower and upper thicknesses (3, 4) of thermofusible material of at least one thermofusible sheet (F), these thicknesses of thermofusible material being welded together across the non-thermofusible sheet.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: The present invention relates to heterocyclic compounds, their process of preparation, pharmaceutical compositions comprising these compounds and use thereof, optionally in combination with other antibacterial agents and/or beta-lactam compounds, for the prevention or treatment of bacterial infections. The present invention also relates to the use of these compounds as ?-lactamase inhibitors and/or as antibacterial agents.

Abstract: Described herein, amongst other things, is a container preform that is blow moldable into a container. The container preform includes a tubular body having a neck finish and a base at an open end and a closed end thereof respectively. The base is defined between inside and outside curved surfaces at least one of which is composed of multiple tangential curves, wherein an elongate portion is defined between adjacent inside and outside concentric curves that define a thinnest bottom wall thickness of the base having a constant minimum thickness that is smaller than or equal to a wall thickness of the body.

Abstract: Disclosed herein, amongst other things, is a method for converting a design of an original preform that is blow moldable to form a container into a converted preform having less molding material that is blow moldable to form the same container. The method includes retaining a neck finish and body of the original preform on the converted preform. The method further includes replacing the original base of the original preform with a converted base having an outer base surface that joins with an outer body surface of the body at an base split-line of the original base and that fits offset within an outer body surface of the original base, whereby the converted preform has a reduced total length, disregarding any gate vestige that may be formed thereon, relative to a total length of the original preform.

Abstract: The invention relates to a fibrous material for heat-sealable medical packaging comprising a nonwoven fibrous single-layer substrate or a paper impregnated to the core by at least one polyurethane, at least one tackifier and optionally at least one functional additive. It also relates to the process for manufacturing this fibrous material, to the sizing composition used in the manufacturing process and to the medical packaging comprising such a fibrous packaging material.