Abstract: Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.

Abstract: Compounds of Formula (I): wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

Abstract: Vapor provision apparatus including a reservoir housing defining a reservoir for liquid, a liquid transport element for transporting liquid from the reservoir to a vaporizer for vaporization and a channel for the liquid transport element, wherein the channel has a sidewall at least partly defined by a section of the reservoir housing; wherein the liquid transport element comprises a first portion arranged to deliver liquid to the vaporizer and a second portion extending along the channel, wherein the channel has a cross-section that corresponds with the cross-section of the second portion of the liquid transport element in the channel, and wherein the section of the reservoir housing that defines the sidewall of the channel has one or more openings to provide fluid communication between the liquid transport element in the channel and liquid in the reservoir.

Abstract: A vapor provision system including a vapor generation chamber, a reservoir containing liquid, a vaporizer located in the vapor generation chamber and a liquid transport element arranged to transport liquid from the reservoir through an opening in a wall of the vapor generation chamber to the vaporizer, wherein the liquid transport element in the vapor generation chamber has a cross-sectional area which is greater than that of the opening, and wherein the liquid transport element in the vapor generation chamber abuts the wall surrounding the opening to help prevent leakage.

Abstract: An aerosol source for a vapor provision system includes a vapor-generating element; a reservoir for holding source liquid, the reservoir being bounded by a wall having an opening therein; and a liquid transport element including a first portion arranged to receive liquid from the reservoir via the opening, a second portion peripheral to the first portion, and a third portion arranged to deliver liquid from the first portion to the vapor-generating element; wherein at least part of the second portion is compressed against a section of the wall around the opening, in use, to provide a sealing effect around at least part of the first portion to promote movement of liquid towards the vapor-generating element.

Abstract: Systems and methods for operating a mobile robot is disclosed. The system can include a processor and a plurality of sensors mounted on the mobile robot. The method includes operating the mobile robot to autonomously navigate along a trajectory. While the mobile robot autonomously navigates along the trajectory, the method involves operating the processor to: monitor an angular velocity and a linear velocity of the mobile robot; determine one or more critical sensor regions defined with reference to the mobile robot based at least on the angular velocity and the linear velocity of the mobile robot; and adapt the operation of the plurality of sensors to prioritize capture of sensor data within the one or more critical sensor regions. Each sensor can be operable to capture the sensor data for an adjustable detection region defined with respect to the sensor and the mobile robot.

Abstract: A system for detecting damage to a glass surface particularly vehicle glazing panels such as vehicle windscreens. The system uses a sensor unit disposed proximate the surface and a processor in communication with the sensor unit. The processor is configured to analyse data received from the sensor unit in order to determine the integrity of the surface and a communication unit is configured to output a signal in response to the processor determining that the surface has been damaged. For vehicle glass the system is preferably integrated into the vehicle management and control systems such that the system is active when the vehicle is active or moving. The management and or control system may monitor for instances or situations when changes, such as above threshold changes, occur in order to produce an output warning signal.

Abstract: Apparatus for use in handling windscreens for example for installation in a vehicle, includes a windscreen anchor assembly comprising a windscreen anchor device and a support arm extending away from the windscreen anchor device. A mount assembly is provided for supporting the windscreen anchor assembly. The mount assembly includes a mount structure for engaging with the support arm such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure.

Abstract: A system for detecting damage to a glass surface particularly vehicle glazing panels such as vehicle windscreens. The system uses a sensor unit disposed proximate the surface and a processor in communication with the sensor unit. The processor is configured to analyse data received from the sensor unit in order to determine the integrity of the surface and a communication unit is configured to output a signal in response to the processor determining that the surface has been damaged. For vehicle glass the system is preferably integrated into the vehicle management and control systems such that the system is active when the vehicle is active or moving. The management and or control system may monitor for instances or situations when changes, such as above threshold changes, occur in order to produce an output warning signal.

Abstract: Apparatus for use in handling windscreens for example for installation in a vehicle, includes a windscreen anchor assembly comprising a windscreen anchor device and a support arm extending away from the windscreen anchor device. A mount assembly is provided for supporting the windscreen anchor assembly. The mount assembly includes a mount structure for engaging with the support arm such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure.

Abstract: A system for detecting damage to a glass surface particularly vehicle glazing panels such as vehicle windscreens. The system uses a sensor unit disposed proximate the surface and a processor in communication with the sensor unit. The processor is configured to analyse data received from the sensor unit in order to determine the integrity of the surface and a communication unit is configured to output a signal in response to the processor determining that the surface has been damaged. For vehicle glass the system is preferably integrated into the vehicle management and control systems such that the system is active when the vehicle is active or moving. The management and or control system may monitor for instances or situations when changes, such as above threshold changes, occur in order to produce an output warning signal.

Abstract: A system for detecting damage to a glass surface particularly vehicle glazing panels such as vehicle windscreens. The system uses a sensor unit disposed proximate the surface and a processor in communication with the sensor unit. The processor is configured to analyse data received from the sensor unit in order to determine the integrity of the surface and a communication unit is configured to output a signal in response to the processor determining that the surface has been damaged. For vehicle glass the system is preferably integrated into the vehicle management and control systems such that the system is active when the vehicle is active or moving. The management and or control system may monitor for instances or situations when changes, such as above threshold changes, occur in order to produce an output warning signal.

Abstract: The disclosure relates to compounds of Formula I, or pharmaceutically acceptable salts thereof, Formula (I) as defined herein. Compounds according to Formula I are pharmacologically effective as lysyl oxidase (LOX) inhibitors and are believed to be useful in the treatment of, for instance, cancer.

Abstract: Apparatus for use in handling windscreens for example for installation in a vehicle, includes a windscreen anchor assembly comprising a windscreen anchor device and a support arm extending away from the windscreen anchor device. A mount assembly is provided for supporting the windscreen anchor assembly. The mount assembly includes a mount structure for engaging with the support arm such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure.

Abstract: Apparatus for use in handling windscreens for example for installation in a vehicle, includes a windscreen anchor assembly comprising a windscreen anchor device and a support arm extending away from the windscreen anchor device. A mount assembly is provided for supporting the windscreen anchor assembly. The mount assembly includes a mount structure for engaging with the support arm such that the support arm can slide bodily in its longitudinal direction with respect to the mount structure.

Abstract: A bulk loader system is disclosed that may include a conveyor unit in connection with a fuel-powered engine powering a hydraulic motor. The hydraulic motor may be used to operate the conveyor unit. The system may be configured to function while being mounted on a bed of a truck or be operated as a stand-alone unit. The unit may be sized such that an operator can stand on the deck of the truck along with the unit. The fuel-hydraulic powered motor can enable the conveyor unit to operate at variable speeds. The conveyor unit can be adjustable to facilitate controlling the direction of the material being transported via the conveyor. Some embodiments can include operating the hydraulics of the motor from the Power Take-Off (“PTO”) of the truck. Some embodiments can facilitate operation of the system in a hot or other harsh environment.

Abstract: Arrays for genome-wide analysis of methylation are disclosed. In a preferred aspect arrays comprising a plurality of probes complementary to a plurality of identified CpG islands in the human, mouse and rat genome are disclosed. The arrays may be used to detect methylation within CpG islands in samples from human, mouse and rat genomes.

Abstract: Methods and systems for the determination of a collection of relevant single nucleotide polymorphisms (SNP) probe compatible insertion/deletion probes across a genome to determine probes that can detect a variety of insertions and deletions.

Abstract: A bulk loader system is disclosed that may include a conveyor unit in connection with a fuel-powered engine powering a hydraulic motor. The hydraulic motor may be used to operate the conveyor unit. The system may be configured to function while being mounted on a bed of a truck or be operated as a stand-alone unit. The unit may be sized such that an operator can stand on the deck of the truck along with the unit. The fuel-hydraulic powered motor can enable the conveyor unit to operate at variable speeds. The conveyor unit can be adjustable to facilitate controlling the direction of the material being transported via the conveyor. Some embodiments can include operating the hydraulics of the motor from the Power Take-Off (“PTO”) of the truck. Some embodiments can facilitate operation of the system in a hot or other harsh environment.

Abstract: A bulk loader system is disclosed that may include a conveyor unit in connection with a fuel-powered engine powering a hydraulic motor. The hydraulic motor may be used to operate the conveyor unit. The system may be configured to function while being mounted on a bed of a truck or be operated as a stand-alone unit. The unit may be sized such that an operator can stand on the deck of the truck along with the unit. The fuel-hydraulic powered motor can enable the conveyor unit to operate at variable speeds. The conveyor unit can be adjustable to facilitate controlling the direction of the material being transported via the conveyor. Some embodiments can include operating the hydraulics of the motor from the Power Take-Off (“PTO”) of the truck. Some embodiments can facilitate operation of the system in a hot or other harsh environment.