Abstract: A method for integrated professional network expansion during employee onboarding is implemented via a computing system including a processor. The method includes executing, via a network, an enterprise application on a first remote computing system operated by an employer associated with an enterprise, as well as causing surfacing of a professional networking UI on a display of the first remote computing system during the execution of the enterprise application. The method also includes receiving, via the professional networking UI surfaced on the display of the first remote computing system, user input including a specification of onboarding parameters for an employee of the enterprise, where the onboarding parameters correspond to one or more professional networking intentions for the employee. The method further includes causing the enterprise application to be executed on a second remote computing system operated by the employee in accordance with the specified onboarding parameters.

Abstract: A method for friction reduction during professional network expansion is implemented via a computing system including a processor. The method includes executing, via a network, an enterprise application on a remote computing system operated by a user associated with an enterprise and surfacing a professional networking UI on a display of the remote computing system during execution of the enterprise application. The method includes generating parameters that are representative of a connection between the user and each suggested professional contact based on enterprise-level data corresponding to the user and each suggested professional contact and generating friction-reducing UI elements for each suggested professional contact based on the generated parameters.

Abstract: A method for data-driven professional network expansion techniques is implemented via a computing system including a processor. The method includes executing, via a network, an enterprise application on a remote computing system operated by a user associated with an enterprise and surfacing a professional networking UI on a display of the remote computing system during execution of the enterprise application. The method includes accessing enterprise-level data corresponding to the user and the enterprise, extracting parameters associated with the user and the enterprise from the enterprise-level data, and automatically generating, based on the extracted parameters, the user's professional network and a list of suggested professional contacts.

Abstract: The disclosure relates to inhibitors of PCSK9 useful in the treatment of cholesterol lipid metabolism, and other diseases in which PCSK9 plays a role, having the Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, N-oxide, or tautomer thereof, wherein X1, R1, R2, R3, R4, R5, R6, R6?, R7, R7?, R8, R9, R9?, R10, R11, R12, and n are described herein.

Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Abstract: In various representative aspects, a cleaning system for paint rollers that also recaptures a paint that is removed from the paint roller during cleaning. The system includes a platform that securely attaches to the top rim of an open paint can and provides a base for vertically fixing a standard paint roller on top of the base so that excess paint can be removed from the roller and recaptured back in the well of the paint can. The exemplary embodiments in this invention offers an improvement over existing systems and methods for 1) cleaning paint rollers and recapturing unused paint from the rollers more efficiently than existing products as well as 2) using the same system to rinse any residual paint from the roller so that the roller can be used again.

Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Abstract: Methods and systems are described to automatically identify, measure, and resolve the problem of confounding audiences for predictive modeling exercises involving classification. An example system is described for recursively executing an algorithm that ingests, at minimum, one or more predictors, an outcome variable, a performance improvement threshold at which the system will terminate, and a maximum recursion depth at which the system will terminate if the performance improvement threshold is not met.

Abstract: The invention provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections, particularly infections caused by herpesviruses.

Abstract: Methods and apparatuses for the analysis of mass spectroscopic (MS) data as well as ultraviolet (UV) absorption data. In particular, described herein are tools and methods to assist in generating annotated peptide maps from a raw MS data.

Abstract: This invention relates to graphical user-interactive displays for use in MS-based analysis of protein impurities, as well as methods and software for generating and using such. One aspect provides a user-interactive display comprising an extracted mass chromatogram (XIC), an MS1 spectrum and an MS2 spectrum, all simultaneously representing a user-selected peptide. Another aspect provides a user interactive display simultaneously presenting paired spectra (XIC, MS1 and/or MS2) for a variant peptide and its corresponding wildtype counterpart.

Abstract: Object merging in an electronic document may be provided. First, a selection of at least two objects within the electronic document may be received. Then, in response to the received selection of the at least two objects, a menu listing a plurality of merge operations configured to be performed on the selected at least two objects may be provided. A merge operation may then be selected, previewed, and applied to the selected at least two objects.

Abstract: This invention relates to graphical user-interactive displays for use in MS-based analysis of protein impurities, as well as methods and software for generating and using such. One aspect provides a user-interactive display comprising an extracted mass chromatogram (XIC), an MS1 spectrum and an MS2 spectrum, all simultaneously representing a user-selected peptide. Another aspect provides a user interactive display simultaneously presenting paired spectra (XIC, MS1 and/or MS2) for a variant peptide and its corresponding wildtype counterpart.

Abstract: This invention relates to graphical user-interactive displays for use in MS-based analysis of protein impurities, as well as methods and software for generating and using such. One aspect provides a user-interactive display comprising an extracted mass chromatogram (XIC), an MS1 spectrum and an MS2 spectrum, all simultaneously representing a user-selected peptide. Another aspect provides a user interactive display simultaneously presenting paired spectra (XIC, MS1 and/or MS2) for a variant peptide and its corresponding wildtype counterpart.

Abstract: A multi-media device interface (18) couples a multi-media device (16) to a portable electronic device (10). Multi-media and other information can be loaded into the portable electronic device (10) from the multi-media device (16) or stored in the multi-media device (16) from the portable electronic device (10). The multi-media device interface (18) queues commands to the multi-media device (16) from the portable electronic device (10) while the multi-media device (16) completes a previously-issued command.

Abstract: A multi-media device interface (18) couples a multi-media device (16) to a portable electronic device (10). Multi-media and other information can be loaded into the portable electronic device (10) from the multi-media device (16) or stored in the multi-media device (16) from the portable electronic device (10). The multi-media device interface (18) queues commands to the multi-media device (16) from the portable electronic device (10) while the multi-media device (16) completes a previously-issued command.

Abstract: Methods and apparatuses for the analysis of mass spectroscopic (MS) data as well as ultraviolet (UV) absorption data. In particular, described herein are tools and methods to assist in generating annotated peptide maps from a raw MS data.

Abstract: Biomarkers useful for identifying treatments for and monitoring treatment of patients with multiple sclerosis (MS) are provided, as well as methods for their identification, methods of diagnosing MS, relapse of MS patients and disease progression in MS patients.

Abstract: Object merging in an electronic document may be provided. First, a selection of at least two objects within the electronic document may be received. Then, in response to the received selection of the at least two objects, a menu listing a plurality of merge operations configured to be performed on the selected at least two objects may be provided. A merge operation may then be selected, previewed, and applied to the selected at least two objects.

Abstract: Object merging in an electronic document may be provided. First, a selection of at least two objects within the electronic document may be received. Then, in response to the received selection of the at least two objects, a menu listing a plurality of merge operations configured to be performed on the selected at least two objects may be provided. A merge operation may then be selected, previewed, and applied to the selected at least two objects.