Abstract: A method is described for producing a pneumococcal capsular polysaccharide protein conjugate in which one or more activated pneumococcal polysaccharides of particular pneumococcal serotypes and carrier protein are separately lyophilized, the separately lyophilized polysaccharides and carrier protein are separately reconstituted in an organic solvent, and the reconstituted polysaccharide and carrier protein are then combined together by Tee-mixing and conjugated together to produce polysaccharide carrier protein conjugates. A plurality of conjugates, each comprising polysaccharides of a particular serotype, may be used to produce multivalent pneumococcal immunogenic compositions having a combination of conjugates for use in vaccines.

Abstract: Techniques are described for managing communications between multiple intercommunicating computing nodes, such as multiple virtual machine nodes hosted on one or more physical computing machines or systems. In some situations, users may specify groups of computing nodes and optionally associated access policies for use in the managing of the communications for those groups, such as by specifying which source nodes are allowed to transmit data to particular destinations nodes. In addition, determinations of whether initiated data transmissions from source nodes to destination nodes are authorized may be dynamically negotiated for and recorded for later use in automatically authorizing future such data transmissions without negotiation. This abstract is provided to comply with rules requiring an abstract, and it is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims.

Abstract: Systems for efficiently starting an engine of a hybrid electric vehicle are provided. An example of a system comprises a first processor and a second processor. The second processor is configured to determine when to start an internal combustion engine, cause energy to be supplied from an energy storage device to a generator/motor to cause the generator/motor and crankshaft to rotate to at least a hold speed, transmit a first instruction to a first processor when determining that the internal combination engine should be started. The first processor does not supply fuel to at least one cylinder of the internal combustion engine in response to the first instruction. The second processor is configured to transmit a second instruction to the first processor after a variable period of time has elapse after the generator/motor or crankshaft has reached at least the hold speed.

Abstract: Systems, methods, and apparatuses are provided for self-contained nucleic acid preparation, amplification, and analysis.

Abstract: Systems for efficiently starting an engine of a hybrid electric vehicle are provided. An example of a system comprises a first processor and a second processor. The second processor is configured to determine when to start an internal combustion engine, cause energy to be supplied from an energy storage device to a generator/motor to cause the generator/motor and crankshaft to rotate to at least a hold speed, transmit a first instruction to a first processor when determining that the internal combination engine should be started. The first processor does not supply fuel to at least one cylinder of the internal combustion engine in response to the first instruction. The second processor is configured to transmit a second instruction to the first processor after a variable period of time has elapse after the generator/motor or crankshaft has reached at least the hold speed.

Abstract: A ceramic package substrate has a recess. This allows a device in that recess to be close to a die attached to the substrate's top side, for better performance. The device may be an array capacitor, an in-silicon voltage regulator, or another device or devices.

Abstract: A protective apparatus is disclosed. The apparatus includes a protective element for positioning over at least a portion of a device to protect the device in a first configuration. A support structure integral with the protective element also forms part of the apparatus. The support structure is configured to support the device in a second configuration. In one arrangement, the protective element includes a first surface and a second surface in which the first surface is configured to be at least partially positioned over and to face the device in the first configuration. The second surface is positioned opposite to the first surface and is configured to be exposed to the environment external to the device in the first configuration. In another arrangement, the support structure includes a slot that runs along the second surface in which the slot is configured to receive the device in the second configuration.

Abstract: A method of facilitating wireless communications between a load controller device and a network component is described. The method can include the step of transitioning the load controller device from a peer-to-peer state in which the load controller device can receive initialization information to a provisioned state in which the load controller device connects to the network component using the initialization information. If there is a disruption in the connection between the load controller device and the network component in the provisioned state, the load controller device can be forced back to the peer-to-peer state from the provisioned state to enable the load controller device to receive new initialization information for reestablishment of the connection between the load controller device and the network component or for establishment of another connection between the load controller device and a different network component.