Abstract: Disclosed herein include antibodies or fragments thereof having specificity to a sarbecovirus spike protein. Also provided are compositions, methods, and kits for using said antibodies or fragments thereof for preventing or treating, for example a coronavirus infection.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: A method for waterflooding of a reservoir in a subterranean formation includes (a) appraising the reservoir to obtain a plurality of physical properties relating to the formation and the oil in the reservoir. The plurality of physical properties include a reservoir pressure and a Bubblepoint pressure of the oil in the reservoir. The method also includes (b) determining that the Bubblepoint pressure is greater than 60% of the reservoir pressure. In addition, the method includes (c) waterflooding the reservoir at a voidage replacement ratio (VRR) less than 1.0 based on the determination in (b).

Abstract: A system for recovering hydrocarbons from a subterranean formation with steam-assisted gravity drainage (SAGD) includes a steam injection well. The steam injection well includes a first portion extending from the surface through an unconsolidated layer of the formation to a consolidated layer of the formation, a second portion extending horizontally through the consolidated layer, and a plurality of third portions extending from the second portion. Each third portion extends upward from the second portion into the unconsolidated layer of the formation and a hydrocarbon reservoir in the unconsolidated layer of the formation. In addition, the system includes a production well. The production well includes a first portion extending from the surface through the unconsolidated and a second portion extending horizontally through the unconsolidated layer. The second portion of the production well is vertically positioned above the second portion of the steam injection well.

Abstract: A method for indicating and detecting correct cable connections within a computer network environment. The method includes determining a topology layout for one or more cables that are connected to one or more system units within a computer network environment. The method includes receiving profile information for the one or more cables and the one or more system units present and determining whether the profile information for the one or more cables and the one or more system units meets requirements for the topology layout. In response to making the determination, the method includes indicating a correct connection between a first cable and a first system unit.

Abstract: A system for recovering hydrocarbons from a subterranean formation includes an upper tunnel extending through the formation. In addition, the system includes a lower tunnel extending through the formation below a portion of the upper tunnel. Further, the system includes a plurality of conduits extending from the upper tunnel through the formation to the lower tunnel. Still further, the system includes a plurality of wellbores extending from the lower tunnel into a hydrocarbon-bearing portion of the formation.

Abstract: Methods, apparatus, and products are disclosed for optimizing a physical data communications topology between a plurality of computing nodes, the physical data communications topology including physical links configured to connect the plurality of nodes for data communications, that include carrying out repeatedly at a predetermined pace: detecting network packets transmitted through the links between each pair of nodes in the physical data communications topology, each network packet characterized by one or more packet attributes; assigning, to each network packet, a packet weight in dependence upon the packet attributes for that network packet; determining, for each pair of nodes in the physical data communications topology, a node pair traffic weight in dependence upon the packet weights assigned to the network packets transferred between that pair of nodes; and reconfiguring the physical links between each pair of nodes in dependence upon the node pair traffic weights.

Abstract: Wake on local area network (LAN) functionality is provided in a multi-root environment. An I/O device, which is share by a plurality of physical hosts, receives the MAC address contained in the wake up packet, then prepares and sends an appropriate wake signal to the targeted host. In one embodiment, the shared I/O device sends an out-of-band wake up signal to each of the physical host computers, wherein the wake up signal is a serial bit stream encoded with the MAC address so that only the physical host having a MAC address matching the MAC address in the wake up signal will be turned on. In another embodiment, the shared I/O device sends a binary ON/OFF signal directly to the targeted physical host computer over a signal line associated with the MAC address.

Abstract: Methods, apparatus, and products are disclosed for optimizing a physical data communications topology between a plurality of computing nodes, the physical data communications topology including physical links configured to connect the plurality of nodes for data communications, that include carrying out repeatedly at a predetermined pace: detecting network packets transmitted through the links between each pair of nodes in the physical data communications topology, each network packet characterized by one or more packet attributes; assigning, to each network packet, a packet weight in dependence upon the packet attributes for that network packet; determining, for each pair of nodes in the physical data communications topology, a node pair traffic weight in dependence upon the packet weights assigned to the network packets transferred between that pair of nodes; and reconfiguring the physical links between each pair of nodes in dependence upon the node pair traffic weights.

Abstract: Methods, apparatus, and products are disclosed for optimizing a physical data communications topology between a plurality of computing nodes, the physical data communications topology including physical links configured to connect the plurality of nodes for data communications, that include carrying out repeatedly at a predetermined pace: detecting network packets transmitted through the links between each pair of nodes in the physical data communications topology, each network packet characterized by one or more packet attributes; assigning, to each network packet, a packet weight in dependence upon the packet attributes for that network packet; determining, for each pair of nodes in the physical data communications topology, a node pair traffic weight in dependence upon the packet weights assigned to the network packets transferred between that pair of nodes; and reconfiguring the physical links between each pair of nodes in dependence upon the node pair traffic weights.

Abstract: Embodiments of the invention address deficiencies of the art in respect to digital signal transmissions and provide a novel and non-obvious fall time accelerator circuit for use in a USB interface. In one embodiment of the invention, the USB interface can include a USB port driver coupled to a host controller driver over a USB bus. The USB interface also can include a fall time accelerator circuit coupled to the USB bus between the USB port driver and the host controller driver. The fall time accelerator circuit can include a pulse signal generator coupled to an inbound signal path from the USB bus and arranged to generate a tunable pulse upon detecting a falling edge of a digital signal on the inbound signal path. The circuit further can include an active timer additionally coupled to the inbound signal path to hold the tunable pulse for a set period of time.

Abstract: Methods, apparatus, and products for detecting an increase in thermal resistance of a heat sink in a computer system, the heat sink dissipating heat for a component of the computer system, the computer system including a fan controlling airflow across the heat sink, the computer system also including a temperature monitoring device, including: measuring, by a monitoring module through use of the temperature monitoring device during operation of the computer system, thermal resistance of the heat sink; determining whether the measured thermal resistance of the heat sink is greater than a threshold thermal resistance, the threshold thermal resistance stored in a thermal profile in non-volatile memory, and if the measured thermal resistance of the heat sink is greater than the threshold thermal resistance, notifying a system administrator.

Abstract: Wake on local area network (LAN) functionality is provided in a multi-root environment. An I/O device, which is share by a plurality of physical hosts, receives the MAC address contained in the wake up packet, then prepares and sends an appropriate wake signal to the targeted host. In one embodiment, the shared I/O device sends an out-of-band wake up signal to each of the physical host computers, wherein the wake up signal is a serial bit stream encoded with the MAC address so that only the physical host having a MAC address matching the MAC address in the wake up signal will be turned on. In another embodiment, the shared I/O device sends a binary ON/OFF signal directly to the targeted physical host computer over a signal line associated with the MAC address.

Abstract: The present invention is directed to the detection of faulty CPU heat sink coupling during system power-up. A method in accordance with an embodiment of the present invention includes: monitoring a slope of a CPU temperature rise from initial system power-up; determining if the slope of the CPU temperature rise exceeds an expected value; and in the case that the slope of the CPU temperature rise exceeds the expected value, indicating an existence of a possible fault (PFA) related to a heat sink coupled to the CPU.

Abstract: A design structure embodied in a machine readable storage medium for designing, manufacturing, and/or testing a memory switching data processing system is provided. The memory switching data processing system includes one or more central processing units (‘CPUs’); random access memory organized in at least two banks of memory modules; one or more memory buses providing communications paths for data among the CPUs and the memory modules; and a flexibly configurable memory bus switch comprising a first configuration adapting the first CPU to a first bank of memory modules and a second CPU to a second bank of memory modules and a second configuration adapting the first CPU to both the first bank of memory modules and the second bank of memory modules.

Abstract: A memory switching data processing system including one or more central processing units (‘CPUs’); random access memory organized in at least two banks of memory modules; one or more memory buses providing communications paths for data among the CPUs and the memory modules; and a flexibly configurable memory bus switch comprising a first configuration adapting the first CPU to a first bank of memory modules and a second CPU to a second bank of memory modules and a second configuration adapting the first CPU to both the first bank of memory modules and the second bank of memory modules.

Abstract: Printed circuit boards for countering signal distortion are disclosed that include: a conductive pathway on a printed circuit board between a transmitter and a receiver, the conductive pathway comprised of traces and vias connected together for conductive transfer of a signal from the transmitter to the receiver; a parasitic element on the printed circuit board, the parasitic element having a parasitic effect that distorts the signal; and one or more passive elements mounted adjacent to the conductive pathway without connecting to the conductive pathway, the passive elements having a corrective effect to reduce the distortion from the parasitic effect on the signal.

Abstract: Methods, apparatus, and products for detecting an increase in thermal resistance of a heat sink in a computer system, the heat sink dissipating heat for a component of the computer system, the computer system including a fan controlling airflow across the heat sink, the computer system also including a temperature monitoring device, including: measuring, by a monitoring module through use of the temperature monitoring device during operation of the computer system, thermal resistance of the heat sink; determining whether the measured thermal resistance of the heat sink is greater than a threshold thermal resistance, the threshold thermal resistance stored in a thermal profile in non-volatile memory, and if the measured thermal resistance of the heat sink is greater than the threshold thermal resistance, notifying a system administrator.

Abstract: Methods, apparatus, and products are disclosed for optimizing a physical data communications topology between a plurality of computing nodes, the physical data communications topology including physical links configured to connect the plurality of nodes for data communications, that include carrying out repeatedly at a predetermined pace: detecting network packets transmitted through the links between each pair of nodes in the physical data communications topology, each network packet characterized by one or more packet attributes; assigning, to each network packet, a packet weight in dependence upon the packet attributes for that network packet; determining, for each pair of nodes in the physical data communications topology, a node pair traffic weight in dependence upon the packet weights assigned to the network packets transferred between that pair of nodes; and reconfiguring the physical links between each pair of nodes in dependence upon the node pair traffic weights.

Abstract: The invention is directed to providing a virtualized blade flash with a management module in a blade server. A method of configuring a blade server according to an embodiment of the invention includes: providing a plurality of blades, wherein each blade comprising: a service processor; a chip set; an at least one central processing unit (CPU); providing a management module in communication with each of the plurality of blades; and adding a virtual flash store at the management module.