Patents by Inventor Christopher D. Hupp

Christopher D. Hupp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TAGGING DNA-ENCODED LIBRARIES
    Publication number: 20210002630
    Abstract: The present invention relates to oligonucleotide-encoded libraries and methods of tagging such libraries. In particular, the methods and oligonucleotides can include one or more 2?-substituted nucleotides, such as 2?-O-methyl or 2?-fluoro nucleotides, and other conditions or reagents to enhance enzyme ligation or one or more chemical functionalities to support chemical ligation.
    Type: Application
    Filed: May 7, 2020
    Publication date: January 7, 2021
    Inventors: Anthony D. KEEFE, Richard W. WAGNER, Alexander LITOVCHICK, Matthew CLARK, John CUOZZO, Ying ZHANG, Paolo A. CENTRELLA, Christopher D. HUPP
  • Methods for tagging DNA-encoded libraries
    Patent number: 10865409
    Abstract: The present invention relates to oligonucleotide-encoded libraries and methods of tagging such libraries. In particular, the methods and oligonucleotides can include one or more 2?-substituted nucleotides, such as 2?-O-methyl or 2?-fluoro nucleotides, and other conditions or reagents to enhance enzyme ligation or one or more chemical functionalities to support chemical ligation.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: December 15, 2020
    Assignee: X-Chem, Inc.
    Inventors: Anthony D. Keefe, Richard W. Wagner, Alexander Litovchick, Matthew Clark, John W. Cuozzo, Ying Zhang, Paolo A. Centrella, Christopher D. Hupp
  • METHODS FOR TAGGING DNA-ENCODED LIBRARIES
    Publication number: 20140315762
    Abstract: The present invention relates to oligonucleotide-encoded libraries and methods of tagging such libraries. In particular, the methods and oligonucleotides can include one or more 2?-substituted nucleotides, such as 2?-O-methyl or 2?-fluoro nucleotides, and other conditions or reagents to enhance enzyme ligation or one or more chemical functionalities to support chemical ligation.
    Type: Application
    Filed: September 7, 2012
    Publication date: October 23, 2014
    Applicant: X-Chem, Inc.
    Inventors: Anthony D. Keefe, Richard W. Wagner, Alexander Litovchick, Matthew Clark, John W. Cuozzo, Ying Zhang, Paolo A. Centrella, Christopher D. Hupp