Patents by Inventor Christopher David John Lennon

Christopher David John Lennon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression System
    Publication number: 20210348205
    Abstract: A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.
    Type: Application
    Filed: July 16, 2021
    Publication date: November 11, 2021
    Applicant: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon, Ian John Hodgson
  • Expression system
    Patent number: 11098335
    Abstract: A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: August 24, 2021
    Assignee: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon, Ian John Hodgson
  • Expression process
    Patent number: 10465220
    Abstract: A process for the production of a target recombinant polypeptide is provided. The process comprises expressing an expression cassette encoding the target polypeptide and co-expressing an expression cassette encoding a mitochondrial foldase. Preferred mitochondrial foldases include Mia 40 and Erv1, and homologs thereof.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: November 5, 2019
    Assignee: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon
  • Expression Vector
    Publication number: 20180057823
    Abstract: An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.
    Type: Application
    Filed: November 15, 2017
    Publication date: March 1, 2018
    Applicant: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon
  • Expression vector
    Patent number: 9845475
    Abstract: An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: December 19, 2017
    Assignee: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon
  • Expression System
    Publication number: 20170240943
    Abstract: A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.
    Type: Application
    Filed: May 8, 2017
    Publication date: August 24, 2017
    Applicant: Fujifilm Diosynth Biotechnologies
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon, Ian John Hodgson
  • Expression system
    Patent number: 9677103
    Abstract: A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: June 13, 2017
    Assignee: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon, Ian John Hodgson
  • Expression Vector
    Publication number: 20160024509
    Abstract: An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.
    Type: Application
    Filed: October 12, 2015
    Publication date: January 28, 2016
    Applicant: FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED
    Inventors: Bhupendra Vallabh KARA, Christopher David John LENNON
  • Expression vector for expression of eukaryotic secretion leader sequence fused with a target polypeptide and methods of use thereof
    Patent number: 9157085
    Abstract: An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.
    Type: Grant
    Filed: June 1, 2009
    Date of Patent: October 13, 2015
    Assignee: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon
  • Expression Process
    Publication number: 20140370543
    Abstract: A process for the production of a target recombinant polypeptide is provided. The process comprises expressing an expression cassette encoding the target polypeptide and co-expressing an expression cassette encoding a mitochondrial foldase. Preferred mitochondrial foldases include Mia 40 and Erv1, and homologs thereof.
    Type: Application
    Filed: November 2, 2011
    Publication date: December 18, 2014
    Applicant: FUJIFILM DIOSYNTH BIOTECHNOLOGIES UK LIMITED
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon
  • Expression System
    Publication number: 20140065670
    Abstract: A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.
    Type: Application
    Filed: August 14, 2013
    Publication date: March 6, 2014
    Applicant: Fujifilm Diosynth Biotechnologies UK Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon, Ian John Hodgson
  • Expression system
    Patent number: 8530188
    Abstract: A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.
    Type: Grant
    Filed: February 1, 2007
    Date of Patent: September 10, 2013
    Assignee: Fujifilm Diosynth Biotechnologies (UK) Limited
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon, Ian John Hodgson
  • Expression Vector
    Publication number: 20110086391
    Abstract: An expression vector for expressing a target polypeptide in a prokaryotic cell is provided. The vector comprises a promoter operably linked to a polynucleotide encoding the target polypeptide operably linked to a eukaryotic secretion leader sequence, the eukaryotic secretion leader sequence encoding a signal peptide sequence selected from the group consisting of: a) MLKRSSWLATLGLLTVASVSTIVYA; b) MKKATFITCLLAVLLVSNPIWNA; c) MKVSAAALAVILIATALCAPASA; d) MKVSTAFLCLLLTVSAFSAQVLA; and e) MKCLLLALGLALACAAQA. Processes for expressing polypeptides and prokaryotic microorganisms comprising such vectors are also provided.
    Type: Application
    Filed: June 1, 2009
    Publication date: April 14, 2011
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon
  • Expression System
    Publication number: 20090170160
    Abstract: A perfect palindrome operator sequence-based protein expression system is provided. The expression system comprises a promoter; and a perfect palindrome operator sequence, wherein the promoter is not T7. The expression system is preferably employed for the production of recombinant proteins by fermentation.
    Type: Application
    Filed: February 1, 2007
    Publication date: July 2, 2009
    Inventors: Bhupendra Vallabh Kara, Christopher David John Lennon, Ian John Hodgson