Patents by Inventor Christopher DERENZO

Christopher DERENZO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • B7-H3 CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20230174653
    Abstract: The present invention provides a chimeric antigen receptor (CAR) comprising an extracellular target-binding domain comprising a B7-H3 binding moiety. The present invention further provides polynucleotides and recombinant vectors encoding such CARs. The present invention further provides isolated host cells and methods for preparing isolated host cells expressing the CARs. The present invention further provides pharmaceutical compositions comprising the isolated host cells and methods for treating a tumor using the pharmaceutical compositions.
    Type: Application
    Filed: April 6, 2021
    Publication date: June 8, 2023
    Applicant: St. Jude Children's Research Hospital, Inc.
    Inventors: Stephen GOTTSCHALK, Christopher DERENZO, Phuong NGUYEN