Abstract: A system including a respiration detection device configured to detect respiration of an individual within a defined environment regardless of a position of the individual within the defined environment wherein detection is performed at a location unobstructed by a physical barrier within the defined environment, a processor with non-transitory computer readable medium configured to evaluate respiration data from the respiration detection device to determine the individual based on a location of the individual within the defined environment and a notification device to provide notification when the individual is detected in the defined environment after at least one of a defined time period and a reduction in respiration. A method is also disclosed.

Abstract: Disclosed herein are compounds useful for detection of glucocorticoid receptor expression and activity via positron emission tomography and related techniques. Methods for preparation and use of the compounds are also described.

Abstract: New methodologies for site-specifically radiolabeling proteins with the PET isotope [1SF] are required to generate high quality radiotracers for imaging in both the preclinical and clinical settings. The enzymatic radiofluorination overcomes many of the limitations encountered to date with purely chemical approaches. The bacterial enzyme lipoic acid ligase was used to conjugate [18F]-fluorooctanoic acid to both a small peptide and a Fab antibody fragment. Labeling was site-specific and highly efficient under mild aqueous conditions using small amounts of peptide/protein (1-10 nmol). The labeled construct retained full epitope binding affinity and was stable in mouse serum. Using an optimized reaction scheme, mCi quantities of [18F]-Fab were generated, an amount sufficient for human imaging.

Abstract: A firearm includes a lower receiver defining a trigger well configured to receive an action, a lower forend extending distally from and monolithically formed with the lower receiver, and an upper forend detachably coupled to the lower forend. The lower forend and the upper forend together define a channel therethrough configured for receipt of a barrel of the firearm. The lower receiver is configured to support the barrel with the length of the barrel free-floating within the channel.

Abstract: A syringe is coupled to a biopsy needle through a coupling structure that includes a motor-driven element such as a gear to rotate the needle. The motor can oscillate back and forth to cause the needle to oscillate. Structures are described to permit one-handed operation of the device and automatic motor activation based on attaining a desired plunger position. Non-electric motors are described along with a mechanism for axial oscillation of the needle.

Abstract: A liner panel for a combustor of a gas turbine engine includes a rail which at least partially defines an impingement cavity. The rail includes a notch which faces toward the impingement cavity. A method of cooling a wall assembly within a combustor for of a gas turbine engine includes directing air through a support shell and a liner panel to form a pressure drop across the support shell that is less than about 80% of a pressure drop across the combustor and to also form a pressure drop across the liner panel greater than about 20% of the pressure drop across the combustor.

Abstract: A firearm includes a lower receiver defining a trigger well configured to receive an action, a lower forend extending distally from and monolithically formed with the lower receiver, and an upper forend detachably coupled to the lower forend. The lower forend and the upper forend together define a channel therethrough configured for receipt of a barrel of the firearm. The lower receiver is configured to support the barrel with the length of the barrel free-floating within the channel.

Abstract: A chassis for a firearm includes a lower receiver and a lower forend that are monolithically formed with one another. The lower receiver defines a trigger well that is configured to receive an action. The lower forend extends distally from the lower receiver and defines a channel that is configured to receive a barrel.

Abstract: A swirler for a combustor of a gas turbine engine includes a swirler outer body with a swirler threaded section defined around a swirler central longitudinal axis. A bulkhead support shell for a combustor of a gas turbine engine includes a swirler boss with a boss threaded section defined around a swirler central longitudinal axis. A combustor of a gas turbine engine includes a bulkhead support shell with a swirler boss. The combustor also includes a swirler mountable to the swirler boss at a threaded interface defined around a swirler central longitudinal axis.

Abstract: A panel for a combustor of a gas turbine engine includes a cold side defining at least one convex portion and at least one concave portion. The concave portion is in communication with a passage. A method of operating a combustor section of a gas turbine engine includes: directing an impingement flow toward a multiple of peaks on a cold side of a panel; directing the impingement flow from the multiple of peaks toward a multiple of troughs with a multiple of entrances on the cold side of the panel; and directing the impingement flow through the multiple of entrances and a respective multiple of effusion passages through the panel.

Abstract: A liner panel for a combustor of a gas turbine engine includes a multiple of heat transfer augmentors. At least one of the multiple of heat transfer augmentors includes a hemi-spherical protuberance.

Abstract: A gas turbine engine includes a vane and a combustor housing that are supported relative to an engine static structure. A retaining assembly clamps the combustor housing and the vane to one another in an axial direction. A circumferential load transfer assembly circumferentially affixes the vane relative to the engine static structure. The retaining assembly is secured to the circumferential load transfer assembly.

Abstract: A chassis for a firearm includes a lower receiver and a lower forend that are monolithically formed with one another. The lower receiver defines a trigger well that is configured to receive an action. The lower forend extends distally from the lower receiver and defines a channel that is configured to receive a barrel.

Abstract: A chassis for a firearm includes sidewalls, a forearm, and a first rail portion. The sidewalls define a trigger well and a magazine well therebetween. The sidewalls also define a proximal portion of a channel. The forearm is monolithically formed with the chassis and extends distally from the magazine well. The forearm defines a distal portion of the channel which is configured to receive a barrel of a firearm. The first rail portion extends from the forearm adjacent the channel on a first side of the chassis. The first rail portion defines part of a rail system that is configured to securely mount an accessory directly to the chassis.

Abstract: A gas turbine engine includes an engine static structure that has a fluid port. A turbine vane is supported relative to the engine static structure and includes a cooling passage. A flow splitter is provided between the engine static structure and the turbine vane. The flow splitter is configured to divide a flow upstream from the flow splitter into a first fluid flow provided to the fluid port and a second fluid flow provided to the cooling passage.