Abstract: A medication delivery device is provided with a stainless steel needle or cannula where the patient end of the needle or cannula has a protective outer layer over the surface of the needle or cannula. The protective outer layer has a thickness and is oriented to prevent or minimize contact of the tissue of the patient with the stainless steel to prevent or inhibit allergic reactions by the tissue contact with the nickel in the stainless steel. The protective outer layer can be a metal coating of a non-allergenic metal, such as gold, or other coating material that is able to cover the exposed surface of the needle to prevent direct contact of the stainless steel with the patient.

Abstract: A topical cooling device for cooling and desensitizing the surface of the skin of a patient is provided that includes a thermally insulating container having at least one side wall, an open end and a closed end, and internal cavity. A thermally transmitting member is included for closing the open end of said container. A refrigerant medium is provided within the cavity of the container and in contact said thermally transmitting member for cooling the surface of the skin of a patient in contact with the thermally transmitting member. The refrigerant medium can be hypertonic aqueous sodium chloride solution. The thermally transmitting member can be flexible bladder that is received within the container where the refrigerant medium is thermally insulated by the container. A lid can be attached to the open end of the container to close the device until ready for use.