Abstract: A cannulator (100) can include a compound needle (104) and a compound cannula (102). The compound needle can include a needle (110), a dilator (108), and a needle hub (106). The dilator can be disposed over the needle with at least a tip of the needle extending beyond a distal end of the dilator. The needle hub can be around a proximal-end portion of the dilator. The compound cannula can include a cannula (140) and a cannula hub (142) around a proximal- end portion of the cannula. The cannulator can have a mated state of the compound needle and the compound cannula for at least cannulation with the cannulator. The mated state of the cannulator can include the dilator disposed in the cannula with a proximal-end portion of the cannula hub coupled to a distal-end portion of the needle hub.

Abstract: Systems, tools, and methods include using a milling assembly with a mill having multiple, different types of cutting element inserts. A gage region of the mill includes a first type of cutting element insert, and a shoulder region of the mill includes a second type of cutting element insert. One cutting element insert may include chip-breaking features, and the other may be a shear or gouging cutting element.

Abstract: A booth structure comprising a roof, a floor and a plurality of slat elements that when stacked together form at least one wall of an enclosure, wherein the slat elements are pre-shaped and stackable in a predefined order to form a door frame for the enclosure, wherein each slat element comprises at least one aperture which when aligned with an aperture of a slat above and/or below form a duct within the wall or walls of the structure.

Abstract: Systems, tools, and methods include using a milling assembly with a mill having multiple, different types of cutting element inserts. A gage region of the mill includes a first type of cutting element insert, and a shoulder region of the mill includes a second type of cutting element insert. One cutting element insert may include chip-breaking features, and the other may be a shear or gouging cutting element.

Abstract: The present invention provides a substantially purified nucleic acid molecule encoding a p/CIP polypeptide, which regulates the activity of CBP/p300-dependent transcription factors. The invention also provides a substantially purified p-CIP polypeptide and active fragments thereof. In addition, the invention provides methods of identifying an effective agent that alters the association of a p/CIP polypeptide with a second protein. Further provided herein are methods of selectively inhibiting signal transduction pathways using an active fragment of a p/CIP polypeptide or a nucleic acid molecule encoding such an acive fragment.