Patents by Inventor Christopher H. Nye

Christopher H. Nye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR INCREASING CAS9-MEDIATED ENGINEERING EFFICIENCY
    Publication number: 20180171360
    Abstract: Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid.
    Type: Application
    Filed: February 2, 2018
    Publication date: June 21, 2018
    Inventors: Peter Sean Cameron, Rachel E. Haurwitz, Andrew P. May, Christopher H. Nye, Megan van Overbeek
  • Methods for increasing CAS9-mediated engineering efficiency
    Patent number: 9970030
    Abstract: Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: May 15, 2018
    Assignee: Caribou Biosciences, Inc.
    Inventors: Peter Sean Cameron, Rachel E. Haurwitz, Andrew P. May, Christopher H. Nye, Megan van Overbeek
  • METHODS FOR INCREASING CAS9-MEDIATED ENGINEERING EFFICIENCY
    Publication number: 20160257973
    Abstract: Methods for use with Type II CRISPR-Cas9 systems for increasing Cas9-mediated genome engineering efficiency are disclosed. The methods can be used to decrease the number of off-target nucleic acid double-stranded breaks and/or to enhance homology-directed repair of a cleaved target nucleic acid.
    Type: Application
    Filed: August 26, 2015
    Publication date: September 8, 2016
    Inventors: Peter Sean Cameron, Rachel E. Haurwitz, Andrew P. May, Christopher H. Nye, Megan van Overbeek