Patents by Inventor Christopher Halsall

Christopher Halsall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinazoline Derivatives
    Publication number: 20070293490
    Abstract: A quinazoline derivative of the formula (I) wherein: R1, R2, R3, R3a, R4, R5, R5a R6, R7, a, m and p are as defined in the description. Also claimed are pharmaceutical compositions containing the quinazoline derivative, the use of the quinazoline derivatives as medicaments and processes for the preparation of the quinazoline derivative. The quinazoline derivatives of formula (I), are useful in the treatment of hyperproliferative disorders such as a cancer.
    Type: Application
    Filed: January 31, 2005
    Publication date: December 20, 2007
    Inventors: Benedicte Delouvrie, Craig Harris, Laurent Hennequin, Christopher Halsall, Janet Pease, Peter Smith
  • Quinazoline derivatives as tyrosine kinase inhibitors
    Publication number: 20070043009
    Abstract: The invention concerns quinazoline derivatives of the Formula (I); wherein each of R1, R2, W, X1, X2, Z, a and b are as defined in the description; processes for their preparation; pharmaceutical compositions containing them and their use in the manufacture of a medicament for providing an anti-proliferative effect. The quinazoline derivatives of Formula (I) are expected to be useful in the treatment of diseases such as certain cancers mediated by erbB receptor tyrosine kinases, particularly EGFR tyrosine kinase.
    Type: Application
    Filed: September 13, 2004
    Publication date: February 22, 2007
    Inventors: Laurent Francois Hennequin, Christopher Halsall
  • Quinazoline derivatives
    Publication number: 20070043010
    Abstract: The invention concerns a quinazoline derivative of the Formula (I): wherein each of the variables have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.
    Type: Application
    Filed: September 22, 2004
    Publication date: February 22, 2007
    Applicant: ASTRAZENECA UK LIMITED
    Inventors: Robert Bradbury, Christopher Halsall, Jason Kettle, Alleyn Plowright, Laurent Hennequin
  • Quinazoline derivatives
    Publication number: 20070032513
    Abstract: The invention concerns quinazoline derivatives of the Formula I: (A chemical formula should be inserted here—please see paper copy enclosed herewith) wherein each of R1, R2, W, X1, X2, Z, a and b are as defined in the description; processes for their preparation; pharmaceutical compositions containing them and their use in the manufacture of a medicament for providing an anti-proliferative effect. The quinazoline derivatives of Formula I are expected to be useful in the treatment of diseases such as certain cancers mediated by erbB receptor tyrosine kinases, particularly EGFR tyrosine kinase.
    Type: Application
    Filed: September 13, 2004
    Publication date: February 8, 2007
    Inventors: Laurent Hennequin, Christopher Halsall
  • Quinazoline derivatives as antiproliferative agents
    Publication number: 20060287295
    Abstract: The invention concerns quinazoline derivatives of Formula (I), wherein each of R1a, R1b, R2, R3 and a have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases.
    Type: Application
    Filed: September 22, 2004
    Publication date: December 21, 2006
    Inventors: Bernard Barlaam, Laurent Hennequin, Christopher Halsall