Abstract: Disclosed herein are various systems and methods for delivering implantable devices, such as, for example detachable embolic coils. The systems can include an embolic coil mated to a pusher wire via a detachable link comprising first and second engaging members and an expandable member or a sleeve. The expandable member or sleeve can reduce relative movement between the engaging members to inhibit premature detachment and/or jamming of the detachable link as the embolic coil is delivered through a catheter.

Abstract: Apparatus for positioning of a medical device in body tissue includes an angle indexer which mates in at least two positions with an index-key attached to the medical device. The indexer may be hand held or otherwise secured to a separate device, such as an introducer cannula, with the medical device being rotatable relative to the indexer.

Abstract: A device for introducing an embolic coil into a catheter comprises an elongated body defining a longitudinal passage extending therethrough from a first opening at a proximal end thereof to a second opening at a distal end thereof, the elongated body being including a mating portion for conforming to a size and shape of an opening in a hub of a catheter to mate therewith and an embolic coil introducer sheath including a coil receiving lumen extending therethrough, a distal tip of the introducer sheath being dimensioned to be received within a proximal end of the longitudinal passage. Similarly, a method of implanting an embolic coil, comprises inserting a stabilizer into a catheter hub so that a flexible mating portion substantially conforms to a shape of an inner surface of the hub wherein the stabilizer includes a passage extending therethrough from a proximal opening to a distal opening thereof.

Abstract: Medical devices, as well as related systems and methods, are disclosed.

Abstract: Described is a catheter which includes a reinforced polymer shaft. The polymer includes nano particles having a dimension of less than about 6 nm. Described is also a method of forming a medical device. Granules of a selected polymer are prepared. Reinforced granules of the selected polymer are prepared. The reinforced granules include nano particles. The granules and the reinforced granules are then mixed in a ratio selected to obtain a desired concentration of the nano particles. The granules and the reinforced granules are extruded to form a substantially tubular element.

Abstract: Embolic coils, and related components, systems, and methods, are disclosed.

Abstract: A system for treating tissue includes a probe assembly having a cannula, a shaft, and one or more needle electrodes. The shaft has a distal end, a proximal end, and a lumen extending between the distal and proximal ends of the shaft, and is slidable within the lumen of the cannula. Each needle electrode has a lumen that may be placed in communication with a port at a proximal end of the probe assembly, and is configured to deliver an occlusive element to a site. The system may further include an embolization actuator for delivering the occlusive element. A method of treating tissue includes placing an electrode at a site of a treatment region, occluding at least a part of a vessel located adjacent the site by delivering an occlusion element from an electrode, and delivering ablation energy to the site while the vessel is at least partially occluded.

Abstract: An endoluminal device for affixation to a wall of a body lumen having a neck region defined by a relatively narrow width and a shoulder region that diverges from the neck region to a relatively wider width. The device comprises a shoulder portion, which may be part of a bulbous portion, having a diameter profile that conforms to the shoulder region, and, in some embodiments, a plurality of affixation members in an area of the device that typically extends from a distal end of the device through the shoulder portion. In one embodiment, the device comprises an endograft for repair of an aneurysm, such as an abdominal aortic aneurysm (AAA). Methods of using the endograft to inhibit continued diametric expansion of the aneurysm and to inhibit endoleak formation and migration of the endograft are also described.

Abstract: An intraluminally placeable tubular device includes an elongate hollow tubular member having a luminal surface and an exterior surface defining a wall portion therebetween. The hollow tubular member has an open proximal end and an opposed distal end. The wall portion has sufficient self-supporting rigidity to permit the device to be advanced through a body lumen during intraluminal placement. The tubular member includes yarns interconnected in a pattern defining opposed interior and exterior textile surfaces. At least one of the textile surfaces is the body fluid-contacting luminal surface or the body lumen-contacting exterior surface. A textile infusion and/or a textile aspiration valve is also provided. A percutaneously or orificially placeable catheter with such textile valves is provided.

Abstract: Ablation device for creating a lesion within tissue includes an angle indexing apparatus. The angle indexing apparatus includes an index-key and an indexer. The index-key is secured to the ablation device. The indexer is secured in a position relative to which the index-key can move. The index-key is adapted to mate with the indexer in a plurality of positions, thereby allowing operation of the ablation device in a plurality of orientations.

Abstract: A system for treating tissue includes a probe assembly having a cannula, a shaft, and one or more needle electrodes. The shaft has a distal end, a proximal end, and a lumen extending between the distal and proximal ends of the shaft, and is slidable within the lumen of the cannula. Each needle electrode has a lumen that may be placed in communication with a port at a proximal end of the probe assembly, and is configured to deliver an occlusive element to a site. The system may further include an embolization actuator for delivering the occlusive element. A method of treating tissue includes placing an electrode at a site of a treatment region, occluding at least a part of a vessel located adjacent the site by delivering an occlusion element from an electrode, and delivering ablation energy to the site while the vessel is at least partially occluded.

Abstract: A probe assembly and method for ablating tissue is provided. The probe assembly comprises an elongated shaft having a rigid section and a flexible section distally extending from the rigid section. The probe assembly further comprises a tissue penetrating element associated with the flexible section. For example, it can be mounted to the flexible section or can be located on a separate element, such as a trocar that can be disposed within the elongated shaft. The probe assembly further comprises one or more ablative elements, such as electrodes, that is associated with the flexible section. Like the tissue penetrating element, the ablative element(s) can be mounted to the flexible section or can be located on a separate element. Thus, the flexible section of the shaft can be flexed to deflect the tissue penetrating element, so that it can be steered through tissue. In this manner, sensitive anatomical structures can be avoided, e.g.

Abstract: An endoluminal device for affixation to a wall of a body lumen having a neck region defined by a relatively narrow width and a shoulder region that diverges from the neck region to a relatively wider width. The device comprises a shoulder portion, which may be part of a bulbous portion, having a diameter profile that conforms to the shoulder region, and, in some embodiments, a plurality of affixation members in an area of the device that typically extends from a distal end of the device through the shoulder portion. In one embodiment, the device comprises an endograft for repair of an aneurysm, such as an abdominal aortic aneurysm (AAA). Methods of using the endograft to inhibit continued diametric expansion of the aneurysm and to inhibit endoleak formation and migration of the endograft are also described.

Abstract: An intraluminally placeable tubular device includes an elongate hollow tubular member having a luminal surface and an exterior surface defining a wall portion therebetween. The hollow tubular member has an open proximal end and an opposed distal end. The wall portion has sufficient self-supporting rigidity to permit the device to be advanced through a body lumen during intraluminal placement. The tubular member includes yarns interconnected in a pattern defining opposed interior and exterior textile surfaces. At least one of the textile surfaces is the body fluid-contacting luminal surface or the body lumen-contacting exterior surface. A textile infusion and/or a textile aspiration valve is also provided. A percutaneously or orificially placeable catheter with such textile valves is provided.

Abstract: Ablation device for creating a lesion within tissue includes an angle indexing apparatus. The angle indexing apparatus includes an index-key and an indexer. The index-key is secured to the ablation device. The indexer is secured in a position relative to which the index-key can move. The index-key is adapted to mate with the indexer in a plurality of positions, thereby allowing operation of the ablation device in a plurality of orientations.

Abstract: A stent delivery system comprising a stent and at least one tether detachably connected to the stent by a connecting member. In one embodiment, the tether may comprise a conductive material and the connecting member may comprise a material subject to degradation upon application of an electrical current. In another embodiment, the connecting member, the stent, and the tether each may have a mechanical strength, where the strength of the connecting member is less than the strength of the stent and the tether. In yet another embodiment, application of electrical current may weaken the connecting member sufficient to enable detachment of the tether. A method of deploying a stent uses the stent delivery device comprising a tether attached to the stent by a connecting member. The tether may be used for accurate positioning of the stent.

Abstract: A stent includes a first portion which does not substantially lengthen axially upon radial contraction of the first portion and a second portion which lengthens axially upon radial contraction of the second portion. The second portion extends from the first portion and constitutes a free end portion of the stent.

Abstract: A stent comprises a first portion which does not substantially lengthen axially upon radial contraction of the first portion and a second portion which lengthens axially upon radial contraction of the second portion. The second portion extends from the first portion and constitutes a free end portion of the stent.

Abstract: A stent delivery system comprising a stent and at least one tether detachably connected to the stent by a connecting member. In one embodiment, the tether may comprise a conductive material and the connecting member may comprise a material subject to degradation upon application of an electrical current. In another embodiment, the connecting member, the stent, and the tether each may have a mechanical strength, where the strength of the connecting member is less than the strength of the stent and the tether. In yet another embodiment, application of electrical current may weaken the connecting member sufficient to enable detachment of the tether. A method of deploying a stent uses the stent delivery device comprising a tether attached to the stent by a connecting member. The tether may be used for accurate positioning of the stent.

Abstract: An apparatus for reducing a medical device such as a stent in size is formed of cooperating crimping dies which are joined via a crimping die moving device. As the cooperating dies are moved together, an inward force is applied to the medical device to reduce the medical device in size.