Patents by Inventor Christopher J. Mannix

Christopher J. Mannix has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for purification of streptakinase using a reducing agent
    Patent number: 5334384
    Abstract: A process for the separation of streptokinase from contaminating proteins in a streptokinase-containing mixture, which comprises treating the mixture with a reducing agent to reduce disulphide bridges in the contaminating proteins to free thiol groups, contacting the mixture with a reagent R-X wherein R is a group capable of reacting with a free thiol group and X is a group R.sup.1 capable of reacting with a free thiol group or is a thiol-containing matrix, and thereafter separating the resulting chemically modified contaminating proteins from the mixture to provide streptokinase in a form substantially free of contaminating proteins.
    Type: Grant
    Filed: October 17, 1989
    Date of Patent: August 2, 1994
    Assignee: Beecham Group p.l.c.
    Inventors: Christopher J. Mannix, Richard A. G. Smith, Ceri J. Lewis, Julian S. Harber